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Asthma link to increased need for fertility treatment

18 September 2017
Appeared in BioNews 918

Women with asthma are more likely to undergo fertility treatment than those without the disease, suggests new research.

Some 12 percent of pregnant women had received fertility treatment compared with only 7 percent in the control group, found the study at Hvidovre Hospital in Denmark. The findings add to increasing evidence of a relationship between asthma and fertility.

'There is a wealth of existing research linking asthma and hormones and this study adds to our knowledge on the subject,' said Dr Samantha Walker, director of research and policy at Asthma UK, who was not involved in the study.

The 744 pregnant women with asthma who gave birth at the hospital between 2007 and 2013 were each matched to three women without asthma in a control group of 2136. The results of the comparison took into account other factors that could have affected outcomes including age, body mass index, a history of smoking, previous children, and single or same sex partnership. However, the study was not able to take income, lifestyle or socioeconomic factors into account. The results were presented at the European Respiratory Society International Congress in Milan, Italy.

However, the study does not prove that asthma itself reduced fertility. Instead, the researchers suggest their findings show that improving asthma control in women may improve their chances of getting pregnant.

'We don't have the hard-core evidence, but based on what we know, it seems very likely that good asthma control will improve fertility in women with asthma by reducing the time it takes to become pregnant and, therefore, the need for fertility treatment,' said Professor Charlotte Suppli Ulrik who supervised the study at the hospital.

She added: 'However, when it comes to fertility for women, age is a crucial factor - so the message, particularly for women with asthma, is don't wait too long, as it might reduce your chances of having children.'

Professor Suppli Ulrik's team is setting up follow-up studies to further investigate a relationship between asthma and fertility including the effects of good asthma control.

Asthma remains one of the most common chronic conditions for women during their reproductive years. The causes of asthma are not completely understood and both genetic and environmental factors affect its development. In the UK alone, it is estimated that 5.4 million people are currently receiving treatment for asthma.

Asthma linked to increase in need for fertility treatment
International Federation of Gynaecology and Obstetrics |  13 September 2017
Statement: Increased use of fertility treatment in women with asthma
Asthma UK |  13 September 2017
Two studies show links between asthma and fertility treatment, and between e-cigarette vaping in mothers and asthma in offspring
European Respiratory Society |  13 September 2017
10 December 2018 - by Dr Elizabeth Oliver 
Children born to parents who took more than a year to conceive or who used fertility treatment may be at increased risk of developing asthma, according to a new study...
19 February 2018 - by Dr Lanay Griessner 
Women using short-acting asthma inhalers took longer to become pregnant than women using long-acting inhaled asthma medications and those without asthma, researchers from the University of Adelaide in Australia, have found...
26 October 2015 - by Dr Jane Currie 
Low-dose aspirin may increase the chances of pregnancy in certain women, according to a US study...
28 May 2014 - by Nina Chohan 
Cholesterol levels may affect how long it takes to conceive, reports a study that followed couples for one year...
18 November 2013 - by Dr Lanay Griessner 
Researchers in Denmark have found that women with asthma take longer to become pregnant compared to non-asthmatics. The results add to an emerging body of evidence showing that asthma affects fertility...
10 December 2012 - by Dr Charlotte Warren-Gash 
Children born as a result of fertility treatment are more likely to develop asthma, say scientists...
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