'Preimplantation Genetic Diagnosis 2018: Current Practice and Beyond', 9-10 November 2018
Page URL: https://www.bionews.org.uk/page_94530

Scientists use DNA to predict facial features

24 March 2014
Appeared in BioNews 747

A new technique allows scientists to make guesses about what a person's face looks like, by examining just 20 genes in their DNA.

The researchers say it may one day be possible for the procedure to be applied to DNA left at crime scenes: faces could be modelled to help police to narrow the pool of potential suspects.

Dr Peter Claes, the first author of the study, told New Scientist: 'I believe that in five to ten years' time, we will be able to computationally predict a face'.

The researchers placed a grid on 3D models of subjects' faces and measured the spatial coordinates of the grid points. Using statistical methods, they were then able to examine the relationship between variation in the faces, and the differing effects of sex, genomic ancestry and genes that affect the shape of the head and face.

To identify genes in that category, the scientists looked at genes that had previously been found to cause facial deformations when mutated. The thinking was that even when not mutated, normal variation within these genes might affect the appearance of the face and the head.

Facial characteristics are likely to be influenced by selection: environmental factors such as rainfall and local temperatures could influence certain physical features. Similarly, sexual selection may play a role in the development of facial features; fostering a preference for a certain look. Both forms of selection result in the concentration of certain variations in geological areas over time.

For this study, the subjects were of mixed West African and European ancestry, allowing them to understand more about the different contributions made by each gene.

'Probably only five percent of genes show a difference between populations', explained Professor Mark Shriver of Penn State University, USA, who was involved in the research. 'We are using different populations because they have had different environments and different social environments'.

The procedure requires much refinement before it can be used in a forensic setting. A major challenge for the future is working out how just many genes are involved in face shape.

'We use DNA to match an individual or identify an individual, but you can get so much more from DNA', said Professor Shriver. 'Currently we can't go from DNA to a face or from a face to DNA, but it should be possible'.

The technique could also have applications outside forensic science. For example, it could be used to predict the facial features of descendants, deceased ancestors, and even extinct human species.

The study was published in PLOS Genetics.

SOURCES & REFERENCES
3-D model links facial features and DNA
EurekAlert! (press release) |  20 March 2014
DNA could 'draw' an offender's face: First step towards creating genetic mugshots that could make catching crooks easier
Daily Mail |  20 March 2014
Genetic mugshot recreates faces from nothing but DNA
New Scientist |  20 March 2014
Modeling 3D Facial Shape from DNA
PLOS Genetics |  20 March 2014
Scientists Reconstruct Faces From DNA Samples
Forbes |  20 March 2014
RELATED ARTICLES FROM THE BIONEWS ARCHIVE
4 December 2017 - by Martha Henriques 
A total of 49 genes have been found to influence earlobe shape and attachment, new research has found...
11 September 2017 - by Ruth Retassie 
It is possible to predict someone's face using DNA sequencing and machine learning, according to Dr Craig Venter...
23 May 2016 - by Amina Yonis 
Researchers have discovered four genes that play a part in determining the shape of people's noses...
22 June 2015 - by Dr Julia Hill 
New DNA evidence has reignited a longstanding debate over the ownership of a 9000-year-old skeleton, known as Kennewick Man...
18 May 2015 - by Matthew Thomas 
The communities of microbes living in and on the human body – known as the microbiome – differ enough between people that researchers can use them to tell one person from another in a population of hundreds...
28 October 2013 - by Dr Naqash Raja 
Regions of the genome that do not code for proteins have been found to shape facial features, research at the Lawrence Berkeley National Laboratory, USA, has shown...
17 September 2012 - by Daryl Ramai 
Five genes that determine a person’s facial shape have been identified, in a study of almost 10,000 Europeans...
6 December 2010 - by Sarah Pritchard 
A recent disclosure by WikiLeaks of tens of thousands of sensitive diplomatic cables includes instructions to US diplomats to collect biometric information on 'key civilian and military officials' including 'fingerprints, facial images, DNA, and iris scans'....
25 September 2006 - by Laura Goodall 
A developmental gene has been found to provide a connection between several genes involved in the formation of a cleft lip and palate. Researchers at Brigham and Women's Hospital and Harvard Medical School in Massachusetts, US found that when the gene SUMO1 is under-expressed and does not...
HAVE YOUR SAY
Log in to add a Comment.

By posting a comment you agree to abide by the BioNews terms and conditions


Syndicate this story - click here to enquire about using this story.