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Fertility watchdog investigates serious IVF mix-ups at London hospital

3 May 2009
Appeared in BioNews 506

Three couples undergoing IVF treatment at Guy's and St Thomas' Hospital, London, have had to have their embryos destroyed after the clinic used  from the wrong donor to fertilise the eggs.

A spokesman for the clinic said that 'We identified potential problems with the eggs and sperm of three couples. All were notified of the issue and offered counselling and an additional cycle of treatment. No embryos were transferred. This was an unfortunate and one-off incident'.

However, according to the Sunday Times, another mix up occurred at the clinic in 2007 - a poor quality embryo was implanted in a patient even though another, more healthy one was available, and the pregnancy failed. The clinic at Guy's and St Thomas' has now ordered a new tagging system to track all IVF samples. Similar systems are already in use in at least three clinics in England.

The Human Fertilisation and Embryology Authority (HFEA) reportedly warned the hospital in 2007 that preparing multiple different sperm samples in the same area carried a risk of mixing them up. The HFEA says that such serious problems occur only 0.04 per cent of the time, but that it is impossible to entirely eradicate human error.

Sue Avery, consultant embryologist at Birmingham Women's Hospital and a former chairwoman of the Association of Clinical Embryologists, said the sperm mix-ups at Guy's were very serious and that 'we would expect in the case of repetition that the HFEA might want to investigate unless they can be thoroughly satisfied that the centre has taken sufficient action'. The HFEA replied that it takes such incidents very seriously. 'When incidents are reported to us, we will investigate and take action where necessary. The risk of mix-ups is a serious concern for patients, clinics and the HFEA'.

In 2002, following a mix-up of IVF embryos a white couple in Leeds gave birth to black twins, and they had to resort to legal action to determine to whom the babies belonged. The Sunday Times report also mentioned two other 2007 cases in which couples received the wrong embryos, which were not made public at the time.

Hospital used wrong sperm to fertilise eggs
The Daily Telegraph |  26 April 2009
Hospital used wrong sperm to fertilise eggs
The Sunday Times |  26 April 2009
IVF samples to be tagged after hospital mixes up embryos
The Evening Standard |  27 April 2009
7 September 2015 - by Antony Starza-Allen 
A woman who sued a US sperm bank after she gave birth to a mixed-race child has had her claim rejected by an Illinois court, reports the Chicago Tribune...
20 September 2010 - by Ben Jones 
A Canadian doctor is being sued by two of his patients who discovered their children were not genetically related to the believed donors, reports the Canadian newspaper The Globe and Mail...
14 December 2009 - by Dr Vivienne Raper 
The UK's fertility industry regulator, the Human Fertilisation and Embryology Authority (HFEA), is poised to report back this week on embryo mix-ups at Guys and St Thomas' Hospital in London. According to The Sun and Independent newspapers, a HFEA licence committee was due to meet today to review the findings of an investigation into what went wrong at the hospital and how to prevent a repeat incident. The hospital came under scrutiny after the embryos of three women were destr...
2 November 2009 - by Ailsa Stevens 
A mistake at one of London's top fertility clinics has resulted in more than 11 women being treated with genetically abnormal sperm, according to an exposé published in the Independent on Sunday newspaper this week. If passed on, the chromosomal abnormality carried by the sperm could have triggered miscarriages or resulted in the birth of a child with serious chromosomal disorder....
28 September 2009 - by Ailsa Stevens 
A woman from the US has given birth to another couple's baby after being implanted with the wrong embryo during her IVF treatment. Caroline Savage and her husband, Sean found out about the mistake when the clinic rang Mr Savage in February. But rather than abort the pregnancy, as the clinic suggested, the couple have elected to give the child back to its biological parents after the birth....
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