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Glaxo close to finding genetic basis for three common ailments

25 October 1999
By BioNews
Appeared in BioNews 31

The pharmaceutical giant Glaxo Wellcome announced that it is close to identifying the human genes that make some people more susceptible to three common illnesses - migraine, adult-onset diabetes and psoriasis. A new approach to gene sequencing called single nucleotide polymorphism (SNP) mapping located the predisposition genes far quicker than was expected.

Allen Roses, vice-president and director of genetics at Glaxo Wellcome, released the findings at the annual meeting of the American Society of Human Genetics in San Francisco. The findings are the result of a collaboration between Glaxo Wellcome, Duke University, the American Diabetes Association, Griffiths University and the Swedish Psoriasis Group. 'The research we are reporting on does not mean that we can provide cures for these diseases overnight but it certainly provides us with a much better understanding of the genes involved', said Roses. 'Genetics studies of this type are extremely important in investigating the factors that underlie the development of illnesses, and revealing their root causes'.

Drugmaker close to naming genes for 3 ailments
Washington Post |  20 October 1999
Scientists close to finding trigger for migraines
The Independent |  20 October 1999
20 June 2011 - by Chris Chatterton 
Scientists have carried out a large genome-wide association study (GWAS) looking into SNPs (single nucleotide polymorphisms) potentially associated with migraine and have discovered three new genes that may be associated with the condition...
25 October 2010 - by Matthew Smart 
An international research team has published data from a group of studies, which have uncovered new genetic variants associated with the autoimmune disease, psoriasis....
4 October 2010 - by Dr Lux Fatimathas 
International researchers have identified a genetic mutation found in some migraine sufferers, which may be responsible for increased pain sensitivity in the brain and a higher likelihood of a migraine being triggered. The finding could allow new treatments to be developed that target the pain associated with migraines...
1 February 2009 - by Ben Jones 
Three different studies on genetic factors that may contribute to causing psoriasis have identified a number of new specific genetic targets for research. The studies, performed in the US by the University of Michigan; in China and Singapore by the Genome Institute of Singapore and the Anhui...
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