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Genome editing

Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA.

Several approaches are used to achieve these changes, include zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.

Articles using this Glossary Item

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CRISPR gene therapy for sickle cell disease approved by the FDA 12 April 2021 News
Genome editing 'toolkit' to speed up gene therapy development 12 April 2021 News
ORION public dialogue on genome editing 29 March 2021 Comment
Event Review: Spotlight on CRISPR 22 March 2021 Review
Event Review: Curing the Incurable – The promises of genome editing 15 March 2021 Review
Animation Review: Gene Therapy Explained – Changing our body's recipe to treat disease 8 March 2021 Review
Gender based prohibitions in the Human Fertilisation and Embryology Act 8 March 2021 Comment
The 14-day limit should be extended to 28 days 15 February 2021 Comment
TALENs outperforms CRISPR/Cas9 in editing compact DNA 1 February 2021 News
CRISPR shown to dampen gene activity in bacteria 25 January 2021 News
Genome editing delays ageing in mice 25 January 2021 News
Base editing offers hope for child ageing disease 11 January 2021 News
Monkey HIV cut from host DNA by CRISPR 7 December 2020 News
New study on CRISPR: the stake of unintended consequences in embryos 23 November 2020 Comment
Safer, targeted method to deliver CRISPR genome therapy developed 16 November 2020 News
TV Review: Brave New World 16 November 2020 Review
New human tissue screen identifies unknown genes in rare genetic disorder 9 November 2020 News
TV Review: Biohackers 9 November 2020 Review
A Nobel for CRISPR genome editing – and for women scientists 2 November 2020 Comment
New vision from the NIH signals a new era for human genomics 2 November 2020 News
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Events using this Glossary Item

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