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Genome editing

Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA.

Several approaches are used to achieve these changes, include zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.

Articles using this Glossary Item

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Changing the Human Genome: What Next for Germline Genome Editing? 19 July 2021 Comment
CRISPR genome editing blocks SARS-CoV-2 replication 19 July 2021 News
Prenatal base editing corrects lysosomal storage disease 19 July 2021 News
Regulating genomics – the next decade 19 July 2021 Comment
Event Review: Shining a Light on Genetic Disorders – Genetic eye disorders 12 July 2021 Review
Should we edit human embryos' genomes, and if so then how? 12 July 2021 Comment
WHO publishes guidelines for human genome editing 12 July 2021 News
CRISPR genome editing treatment shows promise for genetic disorder 5 July 2021 News
Human organoid gives insight into neural tube development 28 June 2021 News
Book Review: The Code Breaker – Jennifer Douda, gene editing and the future of the human race 14 June 2021 Review
Book Review: CRISPR People – The science and ethics of editing humans 1 June 2021 Review
Retron genome editing approach is faster and easier than CRISPR 10 May 2021 News
CRISPR genome editing corrects a Duchenne muscular dystrophy deletion mutation in mice 4 May 2021 News
New algorithm developed to improve personalised cancer therapy 4 May 2021 News
Podcast Review: A Brief History of CRISPR – How we learned to edit the genome 4 May 2021 Review
New CRISPR-based gene therapy for single-gene conditions 26 April 2021 News
Making embryos: a new way? 19 April 2021 Comment
Researchers warn of unintended effects from CRISPR genome editing 19 April 2021 News
CRISPR gene therapy for sickle cell disease approved by the FDA 12 April 2021 News
Genome editing 'toolkit' to speed up gene therapy development 12 April 2021 News
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Events using this Glossary Item

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