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Genome editing

Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA.

Several approaches are used to achieve these changes, include zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.

Articles using this Glossary Item

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Podcast Review: Mapping Humanity – How modern genetics is changing criminal justice, personalised medicine, and our identities 21 September 2020 Review
CRISPR genome editing improved by enzyme testing 14 September 2020 News
Heritable human genome editing: an insight into the International Commission's report 14 September 2020 Comment
Discovery of a tiny CRISPR protein perfect for human genome editing 27 July 2020 News
CRISPR trial shows promising results for sickle cell and thalassaemia 22 June 2020 News
Event Review: Hacking Darwin - Genetic engineering and the future of humanity 1 June 2020 Review
Enzyme discovered critical to age-related cognitive decline 26 May 2020 News
New CRISPR-based COVID-19 point-of-care diagnostic 11 May 2020 News
Diabetes reversed in mice using CRISPR and stem cell therapy 27 April 2020 News
CRISPR diagnostic test to help kidney transplant patients 20 April 2020 News
Podcast Review: The Gene Gap - Can we trust science to police itself? 6 April 2020 Review
Podcast Review: The Gene Gap - Who decides what should happen next? 30 March 2020 Review
Podcast Review: The Gene Gap - What does it mean to be human? 23 March 2020 Review
Exhibition Review: I:DNA 16 March 2020 Review
CRISPR genome editing used directly in patient's eye 9 March 2020 News
New Cas9 variant reduces off-target CRISPR effects 9 March 2020 News
New CRISPR tool to visualise cells in human organoids 9 March 2020 News
TV Review: Storyville – The gene revolution 24 February 2020 Review
UK Government adviser resigns over eugenics remarks 24 February 2020 News
Event Review: The Gene Gap – Who would you trust to edit the human race? 17 February 2020 Review
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Events using this Glossary Item

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