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X-linked inheritance

A is a mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be expressed (1) in males (who are necessarily hemizygous for the gene mutation because they have only one X chromosome) and (2) in females who are homozygous for the gene mutation (i.e., they have a copy of the gene mutation on each of their two X chromosomes).

 

 

Articles using this Glossary Item

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RNA editing tools could create new disease therapies 30 October 2017 News
Radio Review: One to One - Jane Hill meets Caroline Harding 5 June 2017 Review
First human trial of gene therapy for Fabry disease 17 February 2017 News
CRISPR corrects mutation that causes blindness 1 February 2016 News
Radio Review: One to One - Jane Hill Meets Caroline Harding 28 April 2014 Review
Gene therapy looking good for inherited blindness 16 January 2014 News
'Female chromosome' might make a man a man 29 July 2013 News
Wealthy couples flock to USA to avoid UK sex selection ban, IVF medic claims 3 September 2012 News
Book Review: Ethical Problems and Genetics Practice 23 July 2012 Review
Gene therapy beneficial but not permanent in serious immune disorder 5 March 2012 News
Sex determination possible at five weeks after conception 23 January 2012 News
Gene therapy breakthrough for blood-clotting disease 19 December 2011 News
No immune system? No problem: Gene therapy found for 'bubble babies' 30 August 2011 News
New software successfully identifies rare disease gene 27 June 2011 News
Celebrating 20 years of preimplantation genetic diagnosis 23 July 2010 Comment
Dialogue around cousin marriage is a positive step, but it must be based on fact not fiction 22 March 2010 Comment
Families with monogenic disease 30 November 2009 Comment
Gene therapy halts deadly hereditary brain disease in two boys 8 November 2009 News
Progress in free fetal DNA (ffDNA)-based prenatal tests 15 September 2008 Comment
Boy in UK gene therapy trial develops leukaemia 7 January 2008 News
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Events using this Glossary Item

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