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Off-target effects

Unintended changes to a genome, away from the desired target site, which occur as a consequence of genome editing.

Articles using this Glossary Item

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Podcast Review: Mapping Humanity – How modern genetics is changing criminal justice, personalised medicine, and our identities 21 September 2020 Review
CRISPR genome editing improved by enzyme testing 14 September 2020 News
New report gives guidance on genome editing for heritable diseases 7 September 2020 News
Genome editing in human embryos has unintended side-effects 29 June 2020 News
CRISPR can now target RNA - including coronavirus genome 23 March 2020 News
New Cas9 variant reduces off-target CRISPR effects 9 March 2020 News
Stem cell therapy cures diabetes in mice 2 March 2020 News
Event Review: The Gene Gap – Who would you trust to edit the human race? 17 February 2020 Review
Improved base-editors advance CRISPR based genome editing 17 February 2020 News
CRISPR-edited cells for cancer treatment appear safe 10 February 2020 News
Chinese scientist who created genome-edited babies jailed 6 January 2020 News
Human genome editing: what about the protection of egg donors in research? 9 December 2019 Comment
Unpublished paper surfaces about the Chinese genome-edited babies 9 December 2019 News
New 'prime' genome editing offers promise 28 October 2019 News
Event Review: Transforming Medicine - The Promise of Human Genome Editing for Rare and Genetic Disease 16 September 2019 Review
Genome-editing tool offers hope for intractable genetic diseases 2 September 2019 News
Scientist lines up couples for genome-edited babies 8 July 2019 News
Scientist plans to make more genome-edited babies 17 June 2019 News
Commission on heritable genome editing launches, while China clamps down 3 June 2019 News
Germline in the sand: where should we draw the boundaries for genome editing? 15 April 2019 Comment
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Events using this Glossary Item

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