CRISPR Associated Proteins are enzymes that associate with CRISPR RNAs to bind to, and alter DNA or RNA target sequences.
Cas enzymes originate in bacteria and as such a wide variety of types exist. Some are used for genome editing or editing RNA. There are also verions that have been altered in the lab to perform specific tasks.
Common examples include Cas9 which makes a double-stranded break in a target DNA sequence, and Cas13 which targets RNA.
Articles using this Glossary Item
|A Nobel for CRISPR genome editing – and for women scientists||2 November 2020||Comment|
|CRISPR genome editing pioneers win Nobel prize in chemistry||12 October 2020||News|
|CRISPR genome editing improved by enzyme testing||14 September 2020||News|
|Genome editing in mitochondria finally possible||13 July 2020||News|
|E-CRISPR could be used to rapidly detect viruses||18 November 2019||News|
|Scientists base-edit first viable human embryos||28 August 2018||News|
|A different CRISPR enzyme may make genome editing sharper||6 August 2018||News|
|DNA damage from CRISPR 'seriously underestimated'||23 July 2018||News|
|Repetitive behaviours in rare form of autism 'edited out' in mice||2 July 2018||News|
|Genome-editing cells with CRISPR may affect cancer risk||18 June 2018||News|
|UC Berkeley to gain two US CRISPR patents||18 June 2018||News|
|CRISPR scientists win prestigious $1m Kavli award||4 June 2018||News|
|New RNA editing tool shows promise for dementia||19 March 2018||News|