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King's College London - Health: More than a medical matter

Dr Sarah Spain

Dr Sarah Spain is a Volunteer Writer at BioNews, having originally joined the publication under the auspices of its writing scheme. She is a postdoctoral researcher in applied statistical genetics at King's College London's Department of Medical and Molecular Genetics, where her research focuses on the determination of genetic risk factors for complex inflammatory diseases such as Crohn's disease, psoriasis and asthma. Previously she studied Molecular Biology at the University of Kent, then spent two years working in finance. She went on to obtain an MSc in Medical Molecular Biology at the University of Westminster, and a Cancer Research UK supported PhD at University College London, where she worked with Professor Ian Tomlinson on genetic susceptibility to bowel cancer. She is particularly interested in human genetic variation and the genetics of complex diseases.

 


BioNews Review articles written by Dr Sarah Spain:


Event Review: 1000 Genomes Project Community Meeting

30 July 2012 - by Dr Sarah Spain

The 1000 Genomes Project, an initiative to sequence the genetic code of 2,500 people across five continents, has now successfully sequenced over 1,000 people's genomes... [Read More]


BioNews News articles written by Dr Sarah Spain:

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BRCA1 cancer study suggests alternative to major surgery

31 March 2014 - by Dr Sarah Spain

BRCA1 mutations put carriers at high risk of cancer by failing to protect cells against the effects of high levels of oestrogen hormone found in breast and ovary tissue, researchers have established... [Read More]

Lung cancer genetics moves forward

04 November 2013 - by Dr Sarah Spain

Two recent studies have shown how treatments for lung cancer can be tailored to a tumour's genetic make-up, which may ultimately improve existing treatments or even help to identify new ones... [Read More]

Genetic mapping reveals origins of cancer

19 August 2013 - by Dr Sarah Spain

A team of researchers has comprehensively charted the genetic 'signatures' of processes that drive tumour development for the first time... [Read More]

US Supreme Court: Human DNA is a 'product of nature' and cannot be patented

17 June 2013 - by Dr Sarah Spain

The US Supreme Court has unanimously rejected a number of patent claims made by Myriad Genetics on isolated forms of two genes, BRCA1 and BRCA2, associated with an increased risk of breast and ovarian cancer.... [Read More]

Genetic test for asthma may improve treatment

14 January 2013 - by Dr Sarah Spain

Testing children with asthma for a variant in the beta-2 receptor gene may help clinicians determine the most suitable medication, especially in children who respond poorly to standard treatment... [Read More]

Researchers pinpoint gene fault causing deafness

08 October 2012 - by Dr Sarah Spain

US researchers have identified a genetic mutation responsible for the hearing loss that occurs with the condition Usher syndrome type I... [Read More]

Myriad Genetics: landmark ruling for gene patenting

20 August 2012 - by Dr Sarah Spain

In the latest instalment of a highly contested case, the US Federal Circuit Court of Appeals in Washington DC upheld Myriad Genetics' right to patent two genes, BRCA1 and BRCA2,which are associated with the risk of breast and ovarian cancer.... [Read More]

Under right conditions, IVF approaches birth rates of natural conception

02 July 2012 - by Dr Sarah Spain

For the first time, researchers in the USA have calculated cumulative success rates of infertility treatments that use IVF or assisted reproductive technologies (ART), and have showed that overall success rates come close to that of natural conception.... [Read More]

Myriad Genetics breast cancer gene patent ruling sent back to lower court

02 April 2012 - by Dr Sarah Spain

The US Supreme Court has ordered that the two gene patents held by Myriad Genetics be sent back to the US Court of Appeals for the Federal Circuit, to be re-examined... [Read More]

Largest human gene linked to cases of heart disease

20 February 2012 - by Dr Sarah Spain

A mutation in the largest human gene causes 25 percent of a type of inherited heart disease, according to scientists. The information could be incorporated into current genetic tests to provide early diagnosis and clinical intervention... [Read More]

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