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The Fertility Show

Glossary

Germline

Relating to parts of our biology that can be inherited by the next generation (the DNA in egg and sperm cells, and their precursors).



Articles using this Glossary Item

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How should we discuss genome editing in public?

02 October 2017 - by Sandy Starr

What do patients and laypeople think and know about genome editing and its implications? What are the best ways for experts and others to discuss genome editing in public, so as to improve public understanding and avoid confusion? The Progress Educational Trust has set out to answer these questions, with its 'Basic Understanding of Genome Editing' project.... [Read More]

Podcast Review: The Life Scientific - Jennifer Doudna

25 September 2017 - by Rikita Patel

The new era of gene technology presents an exciting approach to treat deleterious, inherited genetic conditions. Presenter Jim Al-Khalili talks to Professor Jennifer Doudna, from her early life to her research into molecular biology, to the development of the CRISPR/Cas9 genome editing system... [Read More]

Book Review: A Crack in Creation - Gene Editing and the Unthinkable Power to Control Evolution

21 August 2017 - by Annabel Slater

I'm glad to see a scientist engaging so strongly in public debate about the use of technology, rather than speculating on the sidelines... [Read More]

We need to talk about... CRISPR

21 August 2017 - by Giulia Cavaliere

Picture this - it's the last day in the office before the summer holidays, you're looking forward to some sunshine and warmth, email auto-response set, and all ready to go. Then, all of a sudden: the news... [Read More]

International genetics groups advocate germline CRISPR research

07 August 2017 - by Dr Greg Ball

Research into human germline genome editing should continue, recommends an international group of 11 human genetics organisations... [Read More]

Radio Review: The Inquiry - Is Gene Editing Out of Control?

31 July 2017 - by Cara Foley

The broadcast by BBC World Service is split into four parts, each with an assigned 'expert witness'. The first chapter tackles 'The Language of Life', aiming to elucidate exactly what DNA, genes and genome editing are... [Read More]

Ovarian cancer drug could treat BRCA-related breast cancer

12 June 2017 - by Dr Loredana Guglielmi

A drug treatment for ovarian cancer has shown success against inherited breast cancer... [Read More]

UK Parliamentary committee publishes report on genomics and genome editing

02 May 2017 - by Sandy Starr

The Science and Technology Committee of the UK Parliament's House of Commons has published a brief report of its wide-ranging inquiry into genomics and genome editing... [Read More]

Podcast Review: CRISPR Updated

27 March 2017 - by Emma Laycock

Radiolab explores the science, the uses and the ethics of CRISPR in this podcast that was two years in the making... [Read More]

Major US report supports human genome editing

20 February 2017 - by Dr Rachel Huddart

An influential advisory group has given cautious support to the idea of making heritable changes to the human genome in order to treat or prevent disease... [Read More]

New genetic links to pancreatic cancer discovered

20 February 2017 - by Jamie Rickman

Researchers have used whole-genome sequencing to uncover new mutations responsible for a rare type of pancreatic cancer... [Read More]

ACMG recommends caution on genome editing

06 February 2017 - by Rachel Siden

The American College of Medical Genetics and Genomics has published a statement recommending caution over the clinical application of genome editing... [Read More]

Therapeutic editing of the human genome – Jewish bioethical perspectives

14 November 2016 - by Dr Avi Lerner

Jewish bioethics may help to broaden the discussion of the ethical concerns that emerge from editing the human genome... [Read More]

Event Review: Gene editing – exploring the Canadian context

12 September 2016 - by Professor Vardit Ravitsky, Professor Bartha Knoppers, Professor Timothy Caulfield, Professor Rosario Isasi, Erika Kleiderman, and Professor Michael Rudnicki

Gene editing, in particular CRISPR/Cas9 technology, is sweeping the scientific world and has been receiving ample attention from policymakers worldwide. Policy statements and academic papers regarding responsible ways of moving forward with gene editing have already been published... [Read More]

NIH to lift moratorium on human–animal chimera research

08 August 2016 - by Antony Blackburn-Starza

The US National Institutes of Health is considering lifting a ban on the funding of research to create human-animal 'chimeras' and replacing it with an ethical review process... [Read More]

Identity, disability and the genome

11 April 2016 - by Dr Felicity Boardman

My research on families living with the genetic disorder Spinal Muscular Atrophy calls into question some of the assumptions underlying the belief that genetic disease is, inherently and by its very definition, a trait to be avoided... [Read More]

Second Chinese team create genetically modified human embryos

11 April 2016 - by Ayala Ochert

A second team in China report that they have created genetically modified human embryos, in an attempt to make them resistant to HIV, using the genome-editing technique CRISPR/Cas9... [Read More]

Mitochondrial replacement techniques: US-style

15 February 2016 - by Dr Peter Mills

The US NAS has published a report on the ethical, social and policy considerations relating to mitochondrial replacement techniques. The recommendation that has inevitably attracted most attention, however, is that only male embryos should be transferred, an approach that was considered but rejected in the UK... [Read More]

Genome editing and CRISPR: The science of engineering the embryo

18 January 2016 - by Dr Jess Buxton

We report from the third session of the annual conference of the Progress Educational Trust, titled 'Genome Editing and CRISPR: The Science of Engineering the Embryo', which discussed these new technologies and how they might be used in the future... [Read More]

Why the UK should be leading the discussion on embryo engineering

11 January 2016 - by Sarah Pritchard

Sir Mark Walport, the UK's Chief Scientific Adviser, gave the keynote address at the Progress Educational Trust's annual conference, where he highlighted the complexity of assessing emerging science and technology, particularly in relation to genome editing... [Read More]

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Events using this Glossary Item

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Published by the Progress Educational Trust

CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Jacques Cohen

Dr Anna Smajdor

Dr Andy Greenfield

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross


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