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Glossary

CRISPR

Clustered regularly-interspaced short palindromic repeats. (in bacteria) segments of DNA used for defence against pathogens; (in genome editing) refers to the CRISPR/Cas system used to edit DNA at specific locations in the genome.



Articles using this Glossary Item

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Book Review: A Crack in Creation - Gene Editing and the Unthinkable Power to Control Evolution

21 August 2017 - by Annabel Slater

I'm glad to see a scientist engaging so strongly in public debate about the use of technology, rather than speculating on the sidelines... [Read More]

We need to talk about…CRISPR

21 August 2017 - by Giulia Cavaliere

Picture this - it's the last day in the office before the summer holidays, you're looking forward to some sunshine and warmth, email auto-response set, and all ready to go. Then, all of a sudden: the news... [Read More]

Dozens of new gene targets for cancer immunotherapy found

14 August 2017 - by Ebtehal Moussa

Over a 100 new genes that may be essential for cancer immunotherapy to work have been identified using a new CRISPR-based screen... [Read More]

EPO awards CRISPR patent to European biotech

14 August 2017 - by Ryan Ross

German-based company MilliporeSigma has announced that the European Patent Office intends to approve its CRISP patent for use on eukaryotic cells... [Read More]

RNA editing with CRISPR could treat genetic diseases

14 August 2017 - by Emma Lamb and Annabel Slater

Scientists have repurposed CRISPR to target the repetitive RNA sequences responsible for several genetic diseases... [Read More]

Disease-causing mutation edited out of human embryos

07 August 2017 - by Charlotte Spicer

Scientists have published their study confirming they are the first to correct a disease-causing mutation in human embryos using genome editing... [Read More]

Gene therapy skin grafts for obesity and diabetes

07 August 2017 - by Annabel Slater

A proof-of-concept study in mice has demonstrated how skin grafts could deliver gene therapy for obesity and diabetes... [Read More]

CRISPR patent dispute ramps up with filing of court appeal

31 July 2017 - by Dr Rachel Brown

The University of California has moved to appeal a decision of the US Patent Trial and Appeal Board over the use of CRISPR in eukaryotic cells... [Read More]

Radio Review: The Inquiry - Is Gene Editing Out of Control?

31 July 2017 - by Cara Foley

The broadcast by BBC World Service is split into four parts, each with an assigned 'expert witness'. The first chapter tackles 'The Language of Life', aiming to elucidate exactly what DNA, genes and genome editing are... [Read More]

US lab may have edited human embryos for first time

31 July 2017 - by Charlotte Spicer

Scientists in the US may have successfully used genome editing in human embryos to correct disease mutations, according to a report by MIT Technology Review... [Read More]

Event Review: Wellcome Collection Packed Lunch - DNA Repair

17 July 2017 - by Charlotte Spicer

It’s not often a PhD student finds themselves with a whole hour to break for lunch. So when asked to review one of the Wellcome Trust’s 'Packed Lunch' talks, I jumped at the chance to make better use of some rare free time. The monthly event, situated at the Euston-based Wellcome Collection, promises to feed your curiosity... [Read More]

Key CRISPR players agree to patent pool

17 July 2017 - by Kulraj Singh Bhangra

The Broad Institute of Massachusetts Institute of Technology and Harvard will take part in an initiative to simplify licensing CRISPR genome editing technology to other organisations and institutions... [Read More]

China sides with Berkeley on CRISPR patent

03 July 2017 - by Rachel Siden

China's State Intellectual Property Office has granted the University of California a patent on CRISPR-Cas9 gene editing technology in the country.

Event Review: Jennifer Doudna talks to Adam Rutherford

03 July 2017 - by Annabel Slater

'This technology really gets the imagination going. It's almost anything that you could imagine wanting to control at the level of genetics, is now in principle within reach.' And the power to control evolution raises important questions of responsibility. This is the message of Professor Jennifer Doudna... [Read More]

CRISPR genome editing may cause unintended mutations

05 June 2017 - by Charlotte Spicer

CRISPR may introduce hundreds of unwanted mutations into the genome, a small study finds... [Read More]

CRISPR gene-editing eliminates HIV in mice

08 May 2017 - by Emma Laycock

US scientists have used CRISPR gene-editing to remove HIV DNA from the genomes of living animals, eliminating further infection.

The CRISPR patent dispute - Europe and the US

02 May 2017 - by Brian Nolan

The European Patent Office and the United States Patent and Trademark Office have been thrust into a dispute pitting the University of California, Berkeley and the University of Vienna against the Broad Institute of MIT and Harvard University. Scientists and inventors have been watching the decisions of the EPO and USPTO because these decisions may leave one of these entities with a patent portfolio worth billions of dollars... [Read More]

UK Parliamentary committee publishes report on genomics and genome editing

02 May 2017 - by Sandy Starr

The Science and Technology Committee of the UK Parliament's House of Commons has published a brief report of its wide-ranging inquiry into genomics and genome editing... [Read More]

Highly sensitive CRISPR diagnostic tool created

24 April 2017 - by Jennifer Willows and Annabel Slater

A new highly sensitive diagnostic system for diseases has been adapted from CRISPR... [Read More]

The media, synthetic biology and CRISPR - fears vs. reality

10 April 2017 - by Sean Byrne

A recent Wall Street Journal article, 'DIY Gene Editing: Fast, Cheap — and Worrisome', describes the Saturday afternoon of teenager, Kian Sadeghi, as he learns to use CRISPR/Cas9 at the Genspace Community Lab in Brooklyn, New York. Like many news articles, the main angle of the article is that new science and technology present a problem... [Read More]

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Events using this Glossary Item

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