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The Fertility Show, Manchester Central, 24-25 March 2018

Glossary

Genome editing

To insert, delete, replace, or alter the expression, of DNA at targeted locations in the genome. Examples include zinc finger nucleases (ZFNs), TALEN and CRISPR/Cas.



Articles using this Glossary Item

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Radio review: Science in Action - CRISPR immunity

05 February 2018 - by Theofanis Michailidis

As a law graduate with a special interest in medical law and bioethics, I admit having very limited scientific background or knowledge... [Read More]

China has treated 86 people with CRISPR genome editing

29 January 2018 - by Meghna Kataria

China has administered CRISPR/Cas9 genome editing to at least 86 cancer patients, a new report has revealed. 

First primates clones using 'Dolly method' created in China

29 January 2018 - by Dr Rachel Huddart

Chinese scientists have announced the successful cloning of monkeys using the same method which produced Dolly the Sheep over 20 years ago... [Read More]

USA announces $190 million for genome editing research

29 January 2018 - by Hannah Tippett Simpson

The US National Institutes of Health (NIH) has announced its intention to grant US$190 million for genome editing research... [Read More]

Podcast Review: Naked Genetics - The Future of Genomic Medicine

22 January 2018 - by Sam Sherratt

Over the last few years we've seen a welcome explosion in the number of scientific podcasts aiming to spread the gospel about new research that may otherwise miss the attention of the mainstream media. With this in mind, I recently sat down to listen to an episode of Naked Genetics, a weekly podcast covering the 'latest genetics news and breakthroughs from the DNA world'... [Read More]

Revolutionising reproduction: setting a new moral compass

22 January 2018 - by Dr Cathy Herbrand

Is sexual reproduction still compatible with Western values? Can germline genome editing ever be considered as medicine? Can we stick to act only on serious disorders? These were some of the provocative and complex questions which were addressed during the last session of the Progress Educational Trust's annual conference... [Read More]

Human immune response may stymie CRISPR genome editing therapies

15 January 2018 - by Rikita Patel

The human adaptive immune response against the Cas9 protein - part of the CRISPR genome editing system – may pose a barrier to new therapies, suggests a new study... [Read More]

What next for genome editing? Politics and the public

15 January 2018 - by Eleanor Taylor

The ever-expanding limits of human reproduction are creating complex ethical and political challenges. One topic that has generated much contention is the possibility of editing the genome of human embryos... [Read More]

Professors Robin Lovell-Badge and Cathy Warwick recognised in New Year's Honours

08 January 2018 - by Sandy Starr

Leading figures in reproductive science and medicine have been recognised in the New Year's Honours list 2018, including two experts who have previously written for BioNews... [Read More]

New CRISPR technique reverses diabetes and kidney failure in mice without cutting DNA

11 December 2017 - by Isobel Steer

Scientists in California have used a modified form of the CRISPR/Cas9 genome editing approach to epigenetically treat diabetes, kidney disease and muscular dystrophy in mice... [Read More]

Real-time film shows CRISPR in action

20 November 2017 - by Helen Robertson

For the first time ever, researchers have been able to film, in real-time, the activity of the CRISPR technique on a strand of DNA... [Read More]

Study uses genome editing inside patient for first time

20 November 2017 - by Jennifer Willows

A new clinical trial in California marks the first time that genome editing has been used inside the body, rather than on cells such as blood or skin which can be extracted, edited outside the body, and then replaced... [Read More]

Canadian scientists call for end to criminal ban on germline genome-editing

13 November 2017 - by Rachel Siden

Members of Canada's Stem Cell Network have called for the country to re-examine its laws banning genome editing research on the human germline... [Read More]

Why germline genome editing may be discriminatory

13 November 2017 - by Dr Calum MacKellar

On the 20th anniversary of the of the 1997 European Convention on Human Rights and Biomedicine (Oviedo Convention), the Council of Europe Committee on Bioethics organised an international conference entitled ‘Relevance and Challenges’ last month in Strasbourg, France... [Read More]

Broad Institute responds to Berkeley CRISPR patent appeal

30 October 2017 - by Jennifer Willows

The Broad Institute has filed arguments ahead of the upcoming CRISPR patent appeal hearing... [Read More]

Event Review: Manchester Science Festival - Reproduction 2.0

30 October 2017 - by Laura O'Donovan

Almost forty years have passed since the 1978 birth of Louise Brown – the first IVF baby – launched a revolution in reproductive medicine resulting in over 250,000 births in the UK alone... [Read More]

New advance in DNA base editing tools

30 October 2017 - by Julianna Photopoulos

Scientists have developed the genome editing technique known as 'base editing' to turn adenine-thymine base pairs back to guanine-cytosine... [Read More]

RNA editing tools could create new disease therapies

30 October 2017 - by Dr Rachel Huddart

A new molecular tool to change individual letters in an RNA sequence may open up new possibilities for gene therapy... [Read More]

'CRISPR-Gold' repairs muscular dystrophy gene in mouse model

09 October 2017 - by Emma Laycock

Scientists have repaired the faulty gene in a mouse model of muscular dystrophy by using gold nanoparticles to deliver the genome editing tool CRISPR-Cas9... [Read More]

Podcast Review: Naked Genetics - Exposing the Contents of Your Genes

09 October 2017 - by Cara Foley

'Would you donate your genome?' Straight to the point, the introduction immediately grabbed my attention. Genome donation wasn't something I had even considered before listening to this podcast, so I was very curious to learn more... [Read More]

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