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King's College London - Health: More than a medical matter


DNA (genetic) sequencing

Determining the order of bases in a DNA molecule.

Articles using this Glossary Item

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New genome sequencing recommendation enables patients to opt out of genetic disease testing

07 April 2014 - by Rebecca Carr

The American College of Medical Genetics and Genomics (ACMG) has updated its position on the return of results from genome sequencing to allow patients to opt out from receiving incidental information.... [Read More]

Synthetic biology moves beyond bacteria and viruses with 'man-made' yeast chromosome

31 March 2014 - by Rhys Baker

The world's first fully-functional synthetic yeast chromosome has been created in an international seven-year effort... [Read More]

Harnessing the 'Angelina effect': Improving care for people with a family history of breast cancer in the UK

31 March 2014 - by Dr Caroline Dalton

As we learn more, and as technologies develop, there are continuing challenges for the NHS to meet in providing the best possible care for people at risk of familial breast cancer... [Read More]

Teenager uncovers genetics behind her own rare cancer

03 March 2014 - by Rhys Baker

A recovering teenage cancer patient is a lead author of a study into the rare form of liver cancer she contracted. The research, published in Science, identified a key mutation that may explain the uncontrolled growth of the tumour... [Read More]

Radio Review: Health Check - Would You Want to Find Out About an Inherited Genetic Condition?

24 February 2014 - by Simon Hazelwood-Smith

Genetic diagnosis of inherited diseases is now routine in the UK, with upwards of 600 different conditions tested for in NHS labs. As genetic sequencing and analysis methods become ever more effective, this figure should grow rapidly over the coming years... [Read More]

Whole genome testing used to guide breast cancer treatment

10 February 2014 - by Barbara Czub

Whole genome testing has been used to guide tailored treatment against advanced breast cancer in a group of 43 patients. The scientists behind the study say their research is a step on the path towards 'personalised medicine' where individual genetic makeup informs treatment choice... [Read More]

Theatre review: How to be Immortal

03 February 2014 - by Simon Hazelwood-Smith

This was a play about death; how people cope with it, how they grieve and how they remember. It was also a play about love and relationships, finding inspiration in unexpected places and also about science, genetics and the story of Henrietta Lacks' cells... [Read More]

Illumina claims the $1,000 genome crown

20 January 2014 - by Dr Rachael Panizzo

The $1,000 genome may have arrived, an achievement which would mark a significant milestone in the application of genetic science... [Read More]

Radio Review: Inside Science - The Personal Genome Project

09 December 2013 - by MarĂ­a Victoria Rivas Llanos

The Personal Genome Project (PGP) was launched in the UK the last November. The project, which was set up in USA in 2005, works on open access of genome sequence information of the 100,000 expected participants... [Read More]

Call for volunteers for open-access genome project

11 November 2013 - by Simon Hazelwood-Smith

The UK branch of the Personal Genome Project has launched, with the aim of sequencing the genomes of 100,000 British volunteers... [Read More]

Lung cancer genetics moves forward

04 November 2013 - by Dr Sarah Spain

Two recent studies have shown how treatments for lung cancer can be tailored to a tumour's genetic make-up, which may ultimately improve existing treatments or even help to identify new ones... [Read More]

Rare Disease Genomes Project to sequence 10,000 whole genomes

28 October 2013 - by Dr Lucy Freem

A three-year joint project to sequence the genomes of 10,000 rare disease patients has been announced by the University of Cambridge, Genomics England and Illumina... [Read More]

23 and your sperm donor?

21 October 2013 - by Dr Ruth Stirton

23andMe describes its Inheritance Calculator as an engaging way for their clients to 'dip their toes into genetics' providing an opportunity to explore the 'fun traits like eye colour and muscle performance'[2] that their offspring might inherit.... [Read More]

Event review: Genetic Testing in Assisted Reproduction - Selecting, Not Perfecting?

14 October 2013 - by James Heather

We had almost made it through the speakers when it happened, just before the break. It was the last speaker who did it. It was Dr Joyce Harper who said what I'd been waiting for, and dropped the Gattaca bomb... [Read More]

Only one in five 'hospital superbug' cases caught in hospital, sequencing study reveals

30 September 2013 - by Matthew Thomas

DNA sequencing of Clostridium difficile samples reveals that the dangerous bacteria, which was previously predominantly transmitted in hospital, is now mostly being caught outside... [Read More]

DNA sequencing gives insight into deadly MERS virus

23 September 2013 - by Lanay Tierney

Middle East Respiratory Syndrome, a potentially lethal respiratory virus first identified last year in Saudi Arabia, may be transmitted by jumping repeatedly from animals to humans, DNA sequencing suggests... [Read More]

Genetic testing set to transform cancer care, says expert

16 September 2013 - by Daniel Riddell

Advances in DNA sequencing mean that high-throughput, routine genetic testing of people with cancer is now a realistic possibility... [Read More]

Genetic test speeds up diagnosis for children with cataracts

16 September 2013 - by Siobhan Chan

A blood test for children born with cataracts will allow faster diagnosis and more personalised treatment, according to researchers at the British Society for Genetic Medicine's annual conference... [Read More]

DNA sequencing has TB in its sights

16 September 2013 - by James Brooks

Scientists have shown how to map tuberculosis outbreaks using DNA sequencing, an advance that could lead to quicker, more effective responses to the potentially lethal bug... [Read More]

Is full genome analysis of newborns worthwhile? $25 million programme to investigate

09 September 2013 - by James Heather

The US National Institutes of Health has unveiled plans to trial sequencing the DNA of newborn babies, to test if it could improve paediatric medical care... [Read More]

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