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Glossary

Clinical trial

A research study in which new ways to prevent, detect, diagnose, or treat disease are tested on human participants.



Articles using this Glossary Item

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FDA to speed up gene therapy and regenerative medicine approvals

20 November 2017 - by Martha Henriques

The US Food and Drug Administration has announced a fast-track review process for gene therapies and other regenerative medicine treatments... [Read More]

Stem cell therapy shows promise in patients with sight loss

20 November 2017 - by Jenny Sharpe

Preliminary results from two early stage clinical trials suggest that embryonic stem cells could be used to treat patients with dry age-related macular degeneration... [Read More]

Study uses genome editing inside patient for first time

20 November 2017 - by Jennifer Willows

A new clinical trial in California marks the first time that genome editing has been used inside the body, rather than on cells such as blood or skin which can be extracted, edited outside the body, and then replaced... [Read More]

FDA approves second gene therapy for cancer

19 October 2017 - by Jennifer Willows

The US Food and Drug Administration have approved the world’s second gene therapy to target blood cancer... [Read More]

Book Review: Bioinformation

16 October 2017 - by Ryan Ross

Since 2011, Polity Books has published a number of books in its 'Resources Series', which have focused on subjects like diamonds, oil and timber. Yet its forthcoming volume marks something of a shift, for its focus is bioinformation... [Read More]

FDA advisors back gene therapy for rare inherited blindness

16 October 2017 - by Rikita Patel

The US Food Drug and Administration advisory committee has backed the use of gene therapy to treat a hereditary disease for the first time... [Read More]

Gene therapy halts fatal child brain disease

09 October 2017 - by Charlotte Spicer

A new gene therapy has halted the progression of a fatal degenerative brain disease in a small study of affected boys... [Read More]

Gene therapy restores vision in blind mice

09 October 2017 - by Dr Kimberley Bryon-Dodd

Gene therapy has restored some vision in mice blinded by retinitis pigmentosa, an inherited degenerative eye disease... [Read More]

Book Review: Stem Cell Dialogues - A Philosophical and Scientific Inquiry into Medical Frontiers

11 September 2017 - by Isobel Steer

Is using and destroying a human embryo for medical research ethical? This question is constantly considered in our newspapers, courtrooms and research labs. You almost certainly have an opinion on it... [Read More]

Gene therapy for cancer halted after patient death

11 September 2017 - by Ebtehal Moussa

Two trials assessing gene therapy for blood cancer have been put on hold by the US Food and Drug Administration, following a patient fatality... [Read More]

First gene therapy for leukaemia approved

04 September 2017 - by Meetal Solanki

The world's first cancer treatment which uses a patient's own genetically modified immune cells has been approved... [Read More]

Stem cells restore neurons in monkey model of Parkinson's disease

04 September 2017 - by Caroline Casey

Neurons derived from human stem cells have successfully been used to treat and relieve symptoms of Parkinson's disease in a primate animal model... [Read More]

Liquid DNA biopsies could be used for cancer screening

21 August 2017 - by Dr Loredana Guglielmi

US researchers have developed a new blood test to detect cancer-related DNA alterations before patients experience symptoms... [Read More]

Vitamin C slows leukaemia in mice by tweaking key gene

21 August 2017 - by Emma Laycock

High doses of vitamin C may help fight certain leukaemias by boosting the activity of a particular gene, suggests a new study... [Read More]

Gene therapy reverses muscular dystrophy in dogs in world first

31 July 2017 - by Jenny Sharpe

A safe and effective gene therapy treating Duchenne muscular dystrophy in dogs has been demonstrated... [Read More]

Supercomputer overcomes key cancer genomics bottleneck

31 July 2017 - by Rikita Patel

The IBM Watson supercomputer can analyse 160 hours' worth of genomic data in just ten minutes... [Read More]

US lab may have edited human embryos for first time

31 July 2017 - by Charlotte Spicer

Scientists in the US may have successfully used genome editing in human embryos to correct disease mutations, according to a report by MIT Technology Review... [Read More]

First personalised vaccines shows promise for skin cancer

10 July 2017 - by Meetal Solanki

A revolutionary vaccine uses the patient’s own immune response to target tumour cells and could be the first step in bespoke, precision medicine. 

Genome study suggests a fifth of adults carry disease mutations

03 July 2017 - by Cara Foley

Approximately 22 percent of healthy adults carry mutations that are associated with disease, found the first ever randomised clinical trial using whole-genome sequencing... [Read More]

Safety matters – can we be sure that CRISPR-Cas9 is not producing unwanted genetic alterations?

03 July 2017 - by Dr Dusko Ilic

Recent debate over the safety of CRISPR-Cas9 genome editing following a study that suggested it can cause hundreds of unexpected mutations left me puzzled... [Read More]

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Published by the Progress Educational Trust

CROSSING FRONTIERS

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Andy Greenfield

Dr Anna Smajdor

Dr Henry Malter

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross

Sandy Starr


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