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The Fertility Show, Manchester Central, 24-25 March 2018

Glossary

Clinical trial

A research study in which new ways to prevent, detect, diagnose, or treat disease are tested on human participants.



Articles using this Glossary Item

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Major mental illnesses share unexpected gene activity

12 February 2018 - by Dr Linda Wijlaars

Several psychiatric disorders – autism, schizophrenia, bipolar disorder and depression – share patterns of gene activity, an international team of scientists has found... [Read More]

High-dose gene therapy appears toxic in monkeys and piglets

05 February 2018 - by Ewa Zotow

Animals given high doses of gene-carrying viruses in a new gene-therapy trial showed signs of severe toxicity.

China has treated 86 people with CRISPR genome editing

29 January 2018 - by Meghna Kataria

China has administered CRISPR/Cas9 genome editing to at least 86 cancer patients, a new report has revealed. 

Blood test for eight common cancers offers promise

22 January 2018 - by Dr Loredana Guglielmi

Scientists have developed a single blood test to detect eight common cancer types and their location of origin within the body... [Read More]

Gene therapy temporarily halts type 1 diabetes in mice

08 January 2018 - by Isobel Steer

A gene therapy has been used to restore normal blood sugar levels in mice with type 1 diabetes, according to a study published this month in the journal Cell Stem Cell.

Gene therapy shows 'mind-blowing' success in treating haemophilia A

18 December 2017 - by Sam Sherratt

A new gene therapy for haemophilia A has exceeded expectations in a recent clinical trial... [Read More]

First trials of Huntington's drug show it could slow disease

11 December 2017 - by Martha Henriques

A breakthrough trial has successfully reduced levels of the harmful protein that causes the neurodegenerative disease Huntington's... [Read More]

Gene therapy hope for haemophilia

11 December 2017 - by Charlotte Spicer

Scientists have successfully used gene therapy to prevent bleeding in a small trial of patients with the inherited blood disorder haemophilia B... [Read More]

FDA okays test for many cancer-causing genes

04 December 2017 - by Theofanis Michailidis

The US Food and Drug Administration has approved a test which can detect cancer-causing mutations in 324 genes... [Read More]

Event Review: Darwin Lecture: from gene identification to clinical benefit - the example of cystic fibrosis

27 November 2017 - by Lea Goetz

The Darwin lecture held at the UK's Royal Society of Medicine in London, and jointly organised with the Linnean Society, gives an annual look at topics in science and medicine.... [Read More]

Confronting unproven stem cell treatments in Australia: The new regulation

20 November 2017 - by Dr Patrick Foong

Stem cell research holds tremendous promise for the treatment of a wide variety of illnesses and conditions, from spinal cord injury to autism. However, much more work is necessary to translate stem cell research into safe and effective therapies... [Read More]

FDA to speed up gene therapy and regenerative medicine approvals

20 November 2017 - by Martha Henriques

The US Food and Drug Administration has announced a fast-track review process for gene therapies and other regenerative medicine treatments... [Read More]

Gene conferring long-life identified in US Amish community

20 November 2017 - by Charlott Repschlager

A rare genetic mutation leading to longer and healthier lives has been discovered in the US Amish community... [Read More]

Stem cell therapy shows promise in patients with sight loss

20 November 2017 - by Jenny Sharpe

Preliminary results from two early stage clinical trials suggest that embryonic stem cells could be used to treat patients with dry age-related macular degeneration... [Read More]

Study uses genome editing inside patient for first time

20 November 2017 - by Jennifer Willows

A new clinical trial in California marks the first time that genome editing has been used inside the body, rather than on cells such as blood or skin which can be extracted, edited outside the body, and then replaced... [Read More]

FDA approves second gene therapy for cancer

19 October 2017 - by Jennifer Willows

The US Food and Drug Administration have approved the world’s second gene therapy to target blood cancer... [Read More]

Book Review: Bioinformation

16 October 2017 - by Ryan Ross

Since 2011, Polity Books has published a number of books in its 'Resources Series', which have focused on subjects like diamonds, oil and timber. Yet its forthcoming volume marks something of a shift, for its focus is bioinformation... [Read More]

FDA advisors back gene therapy for rare inherited blindness

16 October 2017 - by Rikita Patel

The US Food Drug and Administration advisory committee has backed the use of gene therapy to treat a hereditary disease for the first time... [Read More]

Gene therapy halts fatal child brain disease

09 October 2017 - by Charlotte Spicer

A new gene therapy has halted the progression of a fatal degenerative brain disease in a small study of affected boys... [Read More]

Gene therapy restores vision in blind mice

09 October 2017 - by Dr Kimberley Bryon-Dodd

Gene therapy has restored some vision in mice blinded by retinitis pigmentosa, an inherited degenerative eye disease... [Read More]

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