The availability of whole-genome association studies and emerging 'next-generation' sequencing technologies is redefining the genetic architecture of common diseases, revealing new susceptibility genes and offering new clues about mechanisms for a wide range of health disorders. The strategic focus of common disease genetics is progressing from the identification of susceptibility genes – with remarkable successes in the last two years - to understanding the extent to which rare and common variants explain inherited susceptibility to common diseases, to discovery of new disease mechanisms, and to pioneer and evaluate transfer of these advances through to potential clinical application.
Topics addressed at this event will include:
the state of the art in genome-wide association studies across a range of common diseases, including whole genome sequencing;
population genetics, statistics and evolution including common disease challenges in different populations, and biobanks;
efforts to translate common disease genetics to the clinic and to the healthy population, incorporating pharmacogenomics, genomic profiling, utility of risk prediction, public health;
genomics of common cancers and heritable cancer susceptibility;
cell and animal models of common disease genetics;
epigenomics in common diseases, including DNA methylation, clinical studies linking to human disease;
ethical, legal and social implications of personal genetic information.
Attendance fees range from £410 to £830. To register and/or to submit an abstract for a presentation, use this online form or contact Laura Hubbard at or on +44 (0)1223 495 000.
Find out more about genetics in The Rough Guide to Genes and Cloning, coauthored by BioNews Contributing Editor Dr Jess Buxton (buy this book from Amazon UK or Amazon USA); and find out more about fertility/embryology regulation in Human Fertilisation and Embryology: Reproducing Regulation, coedited by BioNews Contributing Editor Dr Kirsty Horsey (buy this book from Amazon UK or Amazon USA).