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Recombinant DNA technology

The creation of new DNA molecules using fragments of DNA from different sources, which can be used to make genetically modified organisms.

Articles using this Glossary Item

US regulator weighs up CRISPR cancer therapy trial

20 June 2016 - by Rachel Reeves

A US federal safety board is set to review an application for the first in-human use of CRISPR/Cas9 genome-editing technology to treat cancer... [Read More]

UNESCO's statement on CRISPR/Cas9 highlights the need for public engagement

12 October 2015 - by Dr Silvia Camporesi and Dr Lara Marks

The UNESCO International Bioethics Committee has released a statement reaffirming an earlier moratorium called by a group of US scientists on the use of CRISPR/Cas9 in human embryos. We argue that the current framing of the debate in terms of dystopic or imagined futures is too narrow and constrains the boundaries of the debate to germline applications... [Read More]

What Gurdon and Yamanaka's Nobel Prize means to the stem cell community

15 October 2012 - by Dr Dusko Ilic

It took 50 years for the Nobel committee to acknowledge one of the key developments in biology... [Read More]

Theatre Review: Frankenstein

20 August 2012 - by John Brinsley

With the term 'Frankenstein' having become synonymous with 'mad scientists' who 'play God', and its status as the go-to criticism against any new technology that threatens to interfere with what is deemed 'natural', Shelley's story is as relevant today as ever it was. Indeed, what was once considered so morally abhorrent that it formed the fabric of horror has, with recombinant DNA, IVF, organ donation and embryonic stem cells to name but a few, been realised today several times over... [Read More]

Book Review: Drawing the Map of Life - Inside the Human Genome Project

10 January 2011 - by Dr Vivienne Raper

The quest to sequence the first human genome has all the ingredients of a good thriller. Privately funded maverick scientist Dr Craig Venter raced the government-sponsored Human Genome Project (HGP) to be the first to sequence the human genetic code. When the draft code was finally published in 2001, it became one of the landmark scientific advances of the last decade... [Read More]

Uncertain future for gene therapy

17 February 2003 - by BioNews

Gene therapy trials for a rare inherited immune disease might be allowed to proceed, but only for patients with no other treatment options, a US advisory panel concluded at an emergency meeting last week. The Recombinant DNA Advisory Committee (RAC) also said that resuming trials for other diseases 'may be... [Read More]

Gene therapy trials to resume

16 December 2002 - by BioNews

US gene therapy trials for a rare immune disorder, suspended after a patient in a similar French trial developed a leukaemia-like disease, should now go ahead, says the Recombinant DNA Advisory Committee (RAC). In October, gene therapy trials for severe combined immunodeficiency (SCID) were halted in several countries, after scientists... [Read More]

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