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The Fertility Show, Manchester Central, 24-25 March 2018



The process by which two DNA molecules exchange genetic information. In meiosis exchange can take place between maternal and paternal chromosomes leading to a novel combination of genetic material in the egg or sperm.

Articles using this Glossary Item


Doubt over human embryo editing study

04 September 2017 - by Annabel Slater

A group of scientists have challenged the landmark study which reported the first successful editing of human embryos for a genetic disease... [Read More]

If you could alter the characteristics of future generations, would you do it?

22 May 2017 - by Dr Peter Mills

The Nuffield Council on Bioethics is seeking views on the reproductive uses of genome editing in humans. Regular readers of BioNews will know that genome editing (including with the CRISPR-Cas9 technique) offers a way of making precisely targeted modifications to DNA in living cells, harnessing the cells’ inbuilt repair mechanisms to repair a deliberate, double-stranded DNA break in a way that may either disable or introduce a functional DNA sequence... [Read More]

Genetic ancestry test claims to find 'village where your DNA was formed'

06 May 2014 - by Matthew Thomas

Geneticists claim to have developed a way of finding where in the world a person's DNA originated... [Read More]

Male chromosome not dying out, say researchers

13 January 2014 - by Matthew Thomas

The human Y chromosome may have some use, after all. Experts previously thought that the chromosome containing 'male' genes was shrinking to the point of extinction... [Read More]

Event Review: GENIE Public Engagement Lectures

22 October 2012 - by Marco Narajos

Bread and beer are not usually things that one would associate with diseases like cancer, dementia or Huntington's disease. This view was proved wrong by geneticists who gathered at the University of Leicester on 9 October 2012 for a series of lectures aimed at the non-scientist. It seems yeast can be inspiration for genetics research too.... [Read More]

A break is not the end: pluripotent stem cell research gives insight on DNA damage disorder

24 September 2012 - by James Brooks

The biological basis of a rare congenital disorder has been clarified, thanks to stem cell technology. The researchers say their work shows how advances in stem cell science can provide insights into genetic conditions... [Read More]

An eggsample of why it is hard to prove a negative

30 July 2012 - by Professor Robin Lovell-Badge

Earlier this year, a paper claimed to have found cells, called ovarian stem cells, in the adult ovaries of both mice and humans. These cells could apparently be grown in large numbers in the lab and could retain the ability to give rise to eggs. A new study finds no evidence for the existence of germline progenitors able to produce eggs in postnatal ovaries. Is a lack of evidence sufficient to win the argument?... [Read More]

Every sperm is special, genome sequencing shows

23 July 2012 - by Antony Blackburn-Starza

Results of the first study to sequence the genomes of individual sperm cells obtained from one person have revealed significant genetic differences between them, confirming the belief that each sperm is unique. It is hoped the technique could be applied in fertility treatments to identify genetic mutations that may occur in the recombination process... [Read More]

Men might escape extinction according to monkey Y chromosome study

27 February 2012 - by Ruth Saunders

Men may not be on the brink of extinction after all, according to a study on the evolution of the human Y chromosome. Previous research has suggested that the Y sex chromosome, carried only by men, is decaying genetically at such a rate that men would become extinct in five million years' time... [Read More]

Females lacking second X-chromosome may have started life 'male'

14 September 2009 - by Lorna Stewart

Turner Syndrome, a condition in which women have only one X chromosome instead of two, may be caused by a missing Y chromosome instead of a missing X as previously thought. Research published in Cell at the start of this month suggests that disruption in the Y chromosome can cause a range of male sex disorders including, surprisingly, Turner Syndrome which has always previously been considered a female sex disorder.... [Read More]

Gene therapy death link can't be ruled out, say experts

24 September 2007 - by Ailsa Stevens

A panel of experts assembled to investigate the death of an Illinois woman, who died unexpectedly after receiving an experimental gene therapy, last week concluded that there was insufficient evidence to suggest the therapy was directly responsible. The death of 36-year-old Jolee Mohr, who was being... [Read More]

Gene 'editing' technique shows promise

08 April 2005 - by BioNews

A gene therapy technique that repairs faulty genes by 'editing' their DNA could lead to new treatments for inherited blood disorders and HIV, say US researchers. The approach could help address safety concerns over current gene therapy methods, many of which rely on specially adapted viruses to deliver working genes... [Read More]

Regulating gene therapy trials

19 June 2000 - by BioNews

A working group set up to advise the US National Institutes of Health (NIH) on the regulation of human gene therapy trials called for a greater involvement of the Recombinant DNA Advisory Committee (RAC), reports last week's Nature. The conduct of gene therapy trials in the US has been subject... [Read More]


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