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Glossary

Mitochondrial inheritance

An unusual pattern of inheritance caused by mutations in genes found in the mitochondria. Mitochondrial genes are always maternally inherited, since sperm contribute no mitochondria to the fertilised egg.



Articles using this Glossary Item

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Call for Australia to allow mitochondrial donation techniques

25 September 2017 - by Jenny Sharpe

A campaign has been launched in Australia to overturn laws preventing couples from accessing mitochondrial donation... [Read More]

Mitochondrial replacement therapies in Mexico and the USA - and the FDA

29 August 2017 - by Dr César Palacios-González

Almost a year after the first live birth of a baby following a mitochondrial replacement technique procedure, the US Food and Drug Administration has sent a very strongly-worded letter to the scientist and team responsible for the event... [Read More]

Controversial doctor to use MRT technique for over 40s fertility

19 June 2017 - by Shaoni Bhattacharya

The fertility doctor who led the team which produced the world's first baby through mitochondrial replacement therapy is now looking to use the same technique in a commercial venture... [Read More]

Event Review: Exploring the sociology of mitochondrial donation

12 June 2017 - by Dr Cathy Herbrand and Dr Rebecca Dimond

The UK's first symposium to discuss the sociology of mitochondrial disorders and novel reproductive technologies took place on 5 May 2017 in London. The event aimed to develop sociological thought around mitochondrial donation, based on invited contributions from social scientists who have conducted empirical research... [Read More]

Autism linked to grandmothers' smoking

02 May 2017 - by Annabel Slater

A higher likelihood of autism spectrum disorder and autistic traits have been linked to maternal grandmothers smoking while pregnant... [Read More]

Mitochondrial replacement techniques, Mexico and the legal unknowns

24 April 2017 - by Dr César Palacios-González

It is not every day that we can examine the details of the first use of a new reproductive technology. But the first live birth of a baby following the use of a mitochondrial replacement technique (MRT) in IVF last year gives a window into just this. The case – with procedures carried out in both the US and Mexico – also raises legal questions... [Read More]

HFEA grants first UK licence to carry out mitochondrial donation

20 March 2017 - by Georgia Everett

Doctors at Newcastle Fertility Centre have been granted the first UK licence to use mitochondrial replacement therapy as a fertility treatment to prevent the inheritance of mitochondrial disease... [Read More]

Expert panel approve cautious use of mitochondrial donation in the UK

05 December 2016 - by Dr Julia Hill

Scientists advising the HFEA have recommended that the technique of mitochondrial replacement therapy be approved for clinical use in the UK... [Read More]

'Three-person babies' grow up into healthy teenagers

31 October 2016 - by Georgia Everett

Seventeen children conceived through ooplasmic transplantation have all matured with regular health and cognitive abilities, according to a study... [Read More]

Mitochondrial donation technique used in Ukraine, doctors claim

17 October 2016 - by Ayala Ochert

Two women in the Ukraine are pregnant with babies conceived through mitochondrial donation as a treatment for infertility, according to a report in New Scientist... [Read More]

Mitochondrial replacement therapy and the welfare of the child

17 October 2016 - by Dr Mair Crouch

The announcement of the birth of the first child conceived using mitochondrial donation was unforeseen. Nonetheless, in any country regulation should be required to protect the interests of the child... [Read More]

World's first mitochondrial donation baby born

03 October 2016 - by Dr Julia Hill

In a world first, the birth of a baby boy who was conceived using mitochondrial donation has been reported... [Read More]

The Mexican mitochondrial fiasco

28 September 2016 - by César Palacios González

Dr John Zhang's team have opened a new door in terms of reproductive possibilities, but they may very well be instrumental in closing the assisted reproductive door for many people in Mexico... [Read More]

Mitochondrial and nuclear DNA mismatch may impact ageing

11 July 2016 - by Dr Julia Hill

The interaction between mitochondrial and nuclear DNA may have implications for health, metabolism and ageing, according to a new study... [Read More]

Sperm self-destruction may lie behind maternal mitochondrial inheritance

04 July 2016 - by Dr Katie Howe

Researchers have identified a gene that, when activated, causes mitochondria inherited from sperm to be destroyed shortly after fertilisation... [Read More]

Video Review: What If My Neighbour's Kid Was Genetically Modified?

04 July 2016 - by Simon Hazelwood-Smith

Paul Knoepfler's TEDx talk covers familiar ground – designer babies, segregation between 'natural' and GM children, unintended side effects, playing god, and eugenics all feature in his dystopian vision of a future involving genetically modified humans... [Read More]

Stem cell study suggests mitochondrial donation might not be 100 percent effective

23 May 2016 - by Dr Rosie Gilchrist

A study has identified a potential problem with mitochondrial donation, an IVF technique that aims to prevent the transmission of faulty mitochondria from mother to child... [Read More]

Mitochondrial replacement techniques: US-style

15 February 2016 - by Dr Peter Mills

The US NAS has published a report on the ethical, social and policy considerations relating to mitochondrial replacement techniques. The recommendation that has inevitably attracted most attention, however, is that only male embryos should be transferred, an approach that was considered but rejected in the UK... [Read More]

Three-person IVF: What makes mitochondrial donation different?

11 January 2016 - by Dr Cathy Herbrand

We report from the second session of the annual conference of the Progress Educational Trust, titled 'From Three-Person IVF to Genome Editing: the Science and the Ethics of Engineering the Embryo', about the newly legalised process of mitochondrial donation... [Read More]

UK mitochondrial donation regulations introduced

02 November 2015 - by Dr Katie Howe

Regulations that came into force this week will enable the UK to be the first country in the world to allow the use of mitochondrial donation techniques during IVF... [Read More]

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