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The Fertility Show

Glossary

Insertion

The addition of one or more nucleotide base pairs into a DNA sequence. Insertions into the coding region of gene (insertion mutations) often stop the gene working.



Articles using this Glossary Item

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Pig organ transplants a step closer as CRISPR removes viruses

14 August 2017 - by Cara Foley

Ancient viral genes have been eliminated from pigs using the genome editing tool CRISPR, according to research... [Read More]

Disease-causing mutation edited out of human embryos

07 August 2017 - by Charlotte Spicer

Scientists have published their study confirming they are the first to correct a disease-causing mutation in human embryos using genome editing... [Read More]

Gene therapy reverses muscular dystrophy in dogs in world first

31 July 2017 - by Jenny Sharpe

A safe and effective gene therapy treating Duchenne muscular dystrophy in dogs has been demonstrated... [Read More]

CRISPR used to record a film in bacteria

17 July 2017 - by Lea Goetz

Scientists have used the CRISPR/Cas system to encode a film in the genomes of living bacteria... [Read More]

Event Review: Wellcome Collection Packed Lunch - DNA Repair

17 July 2017 - by Charlotte Spicer

It’s not often a PhD student finds themselves with a whole hour to break for lunch. So when asked to review one of the Wellcome Trust’s 'Packed Lunch' talks, I jumped at the chance to make better use of some rare free time. The monthly event, situated at the Euston-based Wellcome Collection, promises to feed your curiosity... [Read More]

How new 'molecular scissors' may give crisper CRISPR

10 July 2017 - by Rikita Patel

Researchers have revealed the structure and action of a new type of 'molecular scissors' known as Cpf1, which may improve CRISPR genome editing.

Biotech companies criticise CRISPR mutation study

19 June 2017 - by Charlotte Spicer

Two major biotech companies have criticised a recent study that claimed CRISPR may cause hundreds of unwanted mutations... [Read More]

Gene therapy hope for allergies and asthma

12 June 2017 - by Dr Rachel Huddart

Life-threatening allergies and asthma could one day be treated by a single injection, say researchers who have successfully treated mice using gene therapy... [Read More]

CRISPR genome editing may cause unintended mutations

05 June 2017 - by Charlotte Spicer

CRISPR may introduce hundreds of unwanted mutations into the genome, a small study finds... [Read More]

Blood stem cells produced in the lab for the first time

22 May 2017 - by Paul Waldron

In two different studies, US scientists have succeeded in creating the stem cells which produce blood... [Read More]

GIANT makes short work of height gene discovery

20 February 2017 - by Professor Darren Griffin

A recent large-scale study that discovered 83 rare genes related to human height reveals the power of so-called genome-wide association studies... [Read More]

CRISPR success in repairing sickle-cell anaemia mutation

17 October 2016 - by Sarah Gregory

Researchers have used the CRISPR/Cas9 genome-editing technique to correct the mutation that causes sickle-cell anaemia... [Read More]

Gene therapy halts early Alzheimer's disease in mice

17 October 2016 - by Annabel Slater

A new gene therapy has slowed the progress of early Alzheimer's disease in mice... [Read More]

NIH to lift moratorium on human–animal chimera research

08 August 2016 - by Antony Blackburn-Starza

The US National Institutes of Health is considering lifting a ban on the funding of research to create human-animal 'chimeras' and replacing it with an ethical review process... [Read More]

Mitochondrial and nuclear DNA mismatch may impact ageing

11 July 2016 - by Dr Julia Hill

The interaction between mitochondrial and nuclear DNA may have implications for health, metabolism and ageing, according to a new study... [Read More]

CRISPR cancer therapy trial gets go-ahead in US

27 June 2016 - by Rachel Reeves

The first in-human use of the genome-editing technology CRISPR has been approved by a US federal safety board... [Read More]

MIT CRISPR team turn to RNA

06 June 2016 - by Ayala Ochert and Amina Yonis

The team that developed the CRISPR/Cas9 DNA-editing technique have now developed a new system that could allow RNA editing... [Read More]

Second gene therapy wins approval in Europe

06 June 2016 - by Rachel Reeves

The European Commission has granted marketing authorisation for a gene therapy to treat children with an extremely rare, life-threatening genetic disorder... [Read More]

Gene therapy given green light in Europe

11 April 2016 - by Rebecca Carr

A gene therapy for children with a rare but life-threatening genetic disorder that severely weakens the immune system has been recommended for approval by the European Medicines Agency... [Read More]

Genome editing and CRISPR: The science of engineering the embryo

18 January 2016 - by Dr Jess Buxton

We report from the third session of the annual conference of the Progress Educational Trust, titled 'Genome Editing and CRISPR: The Science of Engineering the Embryo', which discussed these new technologies and how they might be used in the future... [Read More]

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Events using this Glossary Item

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Published by the Progress Educational Trust

CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Jacques Cohen

Dr Anna Smajdor

Dr Andy Greenfield

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross


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