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Preimplantation Genetic Diagnosis: The Who, the What, the Why and the How

Glossary

Heritability

The extent to which a particular trait is inherited. Studies of heritability typically estimate the proportion of observed variation in a particular trait (for example, height) that can be attributed to inherited genetic factors in contrast to environmental ones.



Articles using this Glossary Item

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Mitochondrial replacement therapies in Mexico and the USA - and the FDA

29 August 2017 - by Dr César Palacios-González

Almost a year after the first live birth of a baby following a mitochondrial replacement technique procedure, the US Food and Drug Administration has sent a very strongly-worded letter to the scientist and team responsible for the event... [Read More]

Disease-causing mutation edited out of human embryos

07 August 2017 - by Charlotte Spicer

Scientists have published their study confirming they are the first to correct a disease-causing mutation in human embryos using genome editing... [Read More]

US lab may have edited human embryos for first time

31 July 2017 - by Charlotte Spicer

Scientists in the US may have successfully used genome editing in human embryos to correct disease mutations, according to a report by MIT Technology Review... [Read More]

New gene silencing method discovered

24 July 2017 - by Helen Robertson

US scientists have identified a new mechanism by which genes are silenced, or 'imprinted' during early embryonic development... [Read More]

South Asian social systems give insight into genetics

24 July 2017 - by Charlotte Spicer

Genome-wide analysis in South Asian populations may provide insight into rare genetic diseases, suggests research... [Read More]

Children's visual attention is genetically controlled

17 July 2017 - by Annabel Slater

How infants look at the world is strongly controlled by genetics, a new study has found... [Read More]

Huntington's disease in mice partly reversed using CRISPR

26 June 2017 - by Meghna Kataria

Eliminating the faulty protein that causes Huntingdon's disease goes some way to reversing disease progression in mice, a study has found... [Read More]

Blood test for testicular cancer a step closer

19 June 2017 - by Meetal Solanki

Testing for certain genes could identify men with a ten-fold increased risk of testicular cancer, suggests a new study... [Read More]

Genes for insomnia discovered

19 June 2017 - by Lea Goetz

Researchers have found seven risk genes for insomnia through two large genome-wide and gene-based association studies... [Read More]

Ovarian cancer drug could treat BRCA-related breast cancer

12 June 2017 - by Dr Loredana Guglielmi

A drug treatment for ovarian cancer has shown success against inherited breast cancer... [Read More]

Autism and smoking during pregnancy - a mitochondrial inheritance

30 May 2017 - by Professor David Skuse

In recent years, there has been an explosion in the number of children diagnosed with autism. There is seemingly one in every classroom, most of them boys; some are quiet and nerdy, others may be disruptive and aggressive. Most have normal intelligence, and can be educated in mainstream schools. Parents of such children  question why one child is affected... [Read More]

Daughter wins right to sue father's doctors in confidentiality case

22 May 2017 - by Jennifer Willows

A woman whose father has Huntington’s disease has won the right to sue his doctors for negligence, for failing to tell her... [Read More]

If you could alter the characteristics of future generations, would you do it?

22 May 2017 - by Dr Peter Mills

The Nuffield Council on Bioethics is seeking views on the reproductive uses of genome editing in humans. Regular readers of BioNews will know that genome editing (including with the CRISPR-Cas9 technique) offers a way of making precisely targeted modifications to DNA in living cells, harnessing the cells’ inbuilt repair mechanisms to repair a deliberate, double-stranded DNA break in a way that may either disable or introduce a functional DNA sequence... [Read More]

Radio Review: The Secrets Inside Your Cells - Epigenetics, Trauma and Ancestry

08 May 2017 - by Dr Avi Lerner

The Human Genome Project, completed in April 2003, greatly improved our ability to study human health and disease. It also provided a deeper insight into our history and evolution as a species. Yet a recent episode of the 'Science Friction' radio show, presented by Natasha Mitchell on Australia’s ABC Radio, delved further into these fascinating topics through the lens of the new and emerging field of epigenetics.

Mitochondrial replacement techniques, Mexico and the legal unknowns

24 April 2017 - by Dr César Palacios-González

It is not every day that we can examine the details of the first use of a new reproductive technology. But the first live birth of a baby following the use of a mitochondrial replacement technique (MRT) in IVF last year gives a window into just this. The case – with procedures carried out in both the US and Mexico – also raises legal questions... [Read More]

79 rare obesity-causing genes catalogued

03 April 2017 - by Dr Marianne Kennedy

Seventy-nine rare genetic syndromes in which obesity is a major feature have been catalogued by Canadian researchers... [Read More]

Method behind first successful mitochondrial replacement therapy revealed

03 April 2017 - by Helen Robertson

Details of the world's first successful use of mitochondrial replacement therapy in IVF have been published... [Read More]

New genes linked to brain and ovarian cancer

03 April 2017 - by Annabel Slater

New genes indicating risk of ovarian and brain cancer have been identified using genome-wide association studies... [Read More]

Two-thirds of cancers caused by random mutations

27 March 2017 - by Caroline Casey

A new study has found that up to 66 percent of cancer-causing mutations can be attributed to random mistakes made during DNA replication... [Read More]

Autism linked to cognitive genes

06 March 2017 - by Jamie Rickman

Researchers have discovered that genetic variants associated with Autism Spectrum Disorder (ASD) also correlate with higher intelligence... [Read More]

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Events using this Glossary Item

Darwin's Theory and the Cultural Sciences
08 September 2009 9.15am-12midday Lecture Theatre E, Lecture Theatre Building, University of Surrey, Guildford, Surrey GU2 7XH, UK
An event addressing how Charles Darwin's theory of evolution can be used to examine past and present cultural change...
Genetics and Identity in the Year of Homecoming
27 August 2009 7pm-8.15pm Highland Park Spiegeltent, Charlotte Square Gardens. Charlotte Square, Edinburgh EH2 4DR, UK
A discussion of the relationship between genetic inheritance and Scotland's national self...


Published by the Progress Educational Trust

CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Richard Anderson

Dr Sue Avery

Dr Elizabeth Garner

Professor Allan Pacey

Dr Anna Smajdor

Dr Andy Greenfield

Philippa Taylor

Dr César Palacios-González

Fiona Fox

Sarah Norcross

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