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Glossary

Genetic susceptibility/predisposition

Increased probability - compared to the general population - of developing a disease, due to the presence of one or more gene mutations.



Articles using this Glossary Item

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Seventy-two new gene targets for breast cancer found

30 October 2017 - by Annabel Slater

Two studies have discovered 72 new genetic variants associated with the risk of developing breast cancer... [Read More]

Cancer-causing effect of common chemical pinpointed

05 June 2017 - by Shaoni Bhattacharya

A common chemical found in household products could increase the risk of cancer by blocking the ability of cells to fix genetic flaws which lead to the disease... [Read More]

FDA approves home genetic tests for 10 diseases

10 April 2017 - by Jamie Rickman

The US Food and Drug Administration has approved the first genetic test to estimate an individual's risk of disease that can be sold directly to consumers... [Read More]

Canada passes genetic non-discrimination bill

13 March 2017 - by Rebecca Carr

A bill outlawing genetic discrimination has been passed by Canada's House of Commons, adding genetic characteristics as a protected ground under their Human Rights Act... [Read More]

First genome editing of normal human embryos

13 March 2017 - by Dr Katie Howe

Chinese scientists have successfully used genome editing to correct mutations in viable human embryos for the first time... [Read More]

Neanderthal genes control human gene expression

27 February 2017 - by Annabel Slater and Ari Haque

Neanderthal DNA is still involved in controlling a range of traits in modern humans... [Read More]

Eight percent of tiredness linked to genes

20 February 2017 - by Dr Rosie Gilchrist

A UK Biobank study has found that genetics accounts for eight percent of the difference in people's feelings of tiredness and low energy... [Read More]

Major US report supports human genome editing

20 February 2017 - by Dr Rachel Huddart

An influential advisory group has given cautious support to the idea of making heritable changes to the human genome in order to treat or prevent disease... [Read More]

New genetic links to pancreatic cancer discovered

20 February 2017 - by Jamie Rickman

Researchers have used whole-genome sequencing to uncover new mutations responsible for a rare type of pancreatic cancer... [Read More]

Gene testing in young patients may uncover 'cancer families'

08 August 2016 - by Amina Yonis

More than half of patients with sarcoma, a rare cancer, have mutations that are known to increase the risk of other types of cancer... [Read More]

Genetic risk scores could predict Alzheimer's

11 July 2016 - by Sarah Gregory

Researchers looking at multiple genes have developed risk scores that could identify those most likely to develop Alzheimer's disease in later life... [Read More]

Video Review: What If My Neighbour's Kid Was Genetically Modified?

04 July 2016 - by Simon Hazelwood-Smith

Paul Knoepfler's TEDx talk covers familiar ground – designer babies, segregation between 'natural' and GM children, unintended side effects, playing god, and eugenics all feature in his dystopian vision of a future involving genetically modified humans... [Read More]

Osteoporosis drug touted as potential 'BRCA-blocker'

27 June 2016 - by Helen Robertson

A drug currently used to treat osteoporosis in old age may help prevent breast cancer in women with a genetic predisposition for the disease... [Read More]

Healthy lifestyle reduces risk of common breast-cancer genes

31 May 2016 - by Amina Yonis

Researchers in the USA have found that following a healthy lifestyle can reduce the risk of developing breast cancer among certain women with a strong genetic disposition to the condition... [Read More]

Lab in a lunch box

09 May 2016 - by Craig Macpherson

The development of a portable DNA laboratory for professionals and enthusiasts raises questions about how regulations can possibly protect consumers in this rapidly developing field... [Read More]

No benefit from expanding cancer-risk gene test beyond the essentials

09 May 2016 - by Rachel Siden

Adding more genes to existing multi-gene panels that test for breast and ovarian cancer risk offers little clinical benefit, a study says... [Read More]

More young women with cancer having BRCA testing

22 February 2016 - by Helen Robertson

More than 95 percent of younger women diagnosed with early-onset breast cancer are opting for genetic testing, a study has found... [Read More]

Sure Genomics offers direct-to-consumer whole-genome sequencing

15 February 2016 - by Kulraj Singh Bhangra

US start-up company Sure Genomics has launched the first whole-genome testing service available directly to consumers, for a cost of $2500... [Read More]

Twin study finds that cancer is 33 percent heritable

11 January 2016 - by Dr Lucy Freem

A study involving more than 200,000 Nordic twins has found that cancer is 33 percent heritable... [Read More]

Childhood cancers linked to adult cancer genes

23 November 2015 - by Dr Molly Godfrey

A substantial proportion of childhood cancers are caused by mutations in genes that are known to cause cancer in adults, scientists have found... [Read More]

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