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Glossary

Genetic susceptibility/predisposition

Increased probability - compared to the general population - of developing a disease, due to the presence of one or more gene mutations.



Articles using this Glossary Item

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Cancer-causing effect of common chemical pinpointed

05 June 2017 - by Shaoni Bhattacharya

A common chemical found in household products could increase the risk of cancer by blocking the ability of cells to fix genetic flaws which lead to the disease... [Read More]

FDA approves home genetic tests for 10 diseases

10 April 2017 - by Jamie Rickman

The US Food and Drug Administration has approved the first genetic test to estimate an individual's risk of disease that can be sold directly to consumers... [Read More]

Canada passes genetic non-discrimination bill

13 March 2017 - by Rebecca Carr

A bill outlawing genetic discrimination has been passed by Canada's House of Commons, adding genetic characteristics as a protected ground under their Human Rights Act... [Read More]

First genome editing of normal human embryos

13 March 2017 - by Dr Katie Howe

Chinese scientists have successfully used genome editing to correct mutations in viable human embryos for the first time... [Read More]

Neanderthal genes control human gene expression

27 February 2017 - by Annabel Slater and Ari Haque

Neanderthal DNA is still involved in controlling a range of traits in modern humans... [Read More]

Eight percent of tiredness linked to genes

20 February 2017 - by Dr Rosie Gilchrist

A UK Biobank study has found that genetics accounts for eight percent of the difference in people's feelings of tiredness and low energy... [Read More]

Major US report supports human genome editing

20 February 2017 - by Dr Rachel Huddart

An influential advisory group has given cautious support to the idea of making heritable changes to the human genome in order to treat or prevent disease... [Read More]

New genetic links to pancreatic cancer discovered

20 February 2017 - by Jamie Rickman

Researchers have used whole-genome sequencing to uncover new mutations responsible for a rare type of pancreatic cancer... [Read More]

Gene testing in young patients may uncover 'cancer families'

08 August 2016 - by Amina Yonis

More than half of patients with sarcoma, a rare cancer, have mutations that are known to increase the risk of other types of cancer... [Read More]

Genetic risk scores could predict Alzheimer's

11 July 2016 - by Sarah Gregory

Researchers looking at multiple genes have developed risk scores that could identify those most likely to develop Alzheimer's disease in later life... [Read More]

Video Review: What If My Neighbour's Kid Was Genetically Modified?

04 July 2016 - by Simon Hazelwood-Smith

Paul Knoepfler's TEDx talk covers familiar ground – designer babies, segregation between 'natural' and GM children, unintended side effects, playing god, and eugenics all feature in his dystopian vision of a future involving genetically modified humans... [Read More]

Osteoporosis drug touted as potential 'BRCA-blocker'

27 June 2016 - by Helen Robertson

A drug currently used to treat osteoporosis in old age may help prevent breast cancer in women with a genetic predisposition for the disease... [Read More]

Healthy lifestyle reduces risk of common breast-cancer genes

31 May 2016 - by Amina Yonis

Researchers in the USA have found that following a healthy lifestyle can reduce the risk of developing breast cancer among certain women with a strong genetic disposition to the condition... [Read More]

Lab in a lunch box

09 May 2016 - by Craig Macpherson

The development of a portable DNA laboratory for professionals and enthusiasts raises questions about how regulations can possibly protect consumers in this rapidly developing field... [Read More]

No benefit from expanding cancer-risk gene test beyond the essentials

09 May 2016 - by Rachel Siden

Adding more genes to existing multi-gene panels that test for breast and ovarian cancer risk offers little clinical benefit, a study says... [Read More]

More young women with cancer having BRCA testing

22 February 2016 - by Helen Robertson

More than 95 percent of younger women diagnosed with early-onset breast cancer are opting for genetic testing, a study has found... [Read More]

Sure Genomics offers direct-to-consumer whole-genome sequencing

15 February 2016 - by Kulraj Singh Bhangra

US start-up company Sure Genomics has launched the first whole-genome testing service available directly to consumers, for a cost of $2500... [Read More]

Twin study finds that cancer is 33 percent heritable

11 January 2016 - by Dr Lucy Freem

A study involving more than 200,000 Nordic twins has found that cancer is 33 percent heritable... [Read More]

Childhood cancers linked to adult cancer genes

23 November 2015 - by Dr Molly Godfrey

A substantial proportion of childhood cancers are caused by mutations in genes that are known to cause cancer in adults, scientists have found... [Read More]

FDA warns three US firms over direct-to-consumer genetic testing

16 November 2015 - by Lone Hørlyck

The US Food and Drug Administration has sent warning letters to three gene-testing companies over the marketing and selling of what it claims are direct-to-consumer gene testing products without its approval... [Read More]

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Events using this Glossary Item

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Published by the Progress Educational Trust

CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Jacques Cohen

Dr Anna Smajdor

Dr Andy Greenfield

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross


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