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Glossary

Genetic modification/engineering

The alteration of an organism's or a cell's genetic material using biotechnology techniques.



Articles using this Glossary Item

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Remission in one-third of terminal lymphoma patients after gene therapy

06 March 2017 - by Annabel Slater

A trial gene therapy has reversed terminal blood cancer in a third of patients... [Read More]

First human trial of gene therapy for Fabry disease

17 February 2017 - by Dr Molly Godfrey

A Canadian man with Fabry disease – a rare, inherited enzyme deficiency – is the first person to be given gene therapy for the condition... [Read More]

Deaf mice able to hear 'whispers' after gene therapy

13 February 2017 - by Jamie Rickman

An improved gene-therapy technique using a synthetic virus has restored the hearing of deaf mice up to the level of a whisper... [Read More]

Mouse pancreas grown in rat reverses diabetes

30 January 2017 - by Arit Udoh

Insulin-producing cells from pancreases grown in rats can cure diabetes when transplanted into mice, according to a study... [Read More]

Stable bacteria created using synthetic DNA

30 January 2017 - by Dr James Heather

Scientists have developed bacteria which can live and grow with DNA containing extra 'letters'... [Read More]

Genome editing successfully treats leukaemia

25 January 2017 - by Dr Loredana Guglielmi

Doctors at London's Great Ormond Street Hospital have used genome editing to successfully treat two children with leukaemia... [Read More]

Stem cells reprogrammed to resemble fertilised eggs

23 January 2017 - by Dr Loredana Guglielmi

Researchers have successfully turned stem cells into 'totipotent' cells, with characteristics resembling those of fertilised eggs... [Read More]

23 new genes linked to cancer spread

16 January 2017 - by Dr Loredana Guglielmi

Researchers have identified 23 genes that are linked to metastasis – the spread of cancer cells to other parts of the body... [Read More]

Gene therapy 'reverses ageing' in mice

19 December 2016 - by Sarah Gregory

Gene therapy can reverse the effects of ageing in mice, researchers claim... [Read More]

Gene that 'limits desire for alcohol'

05 December 2016 - by Rachel Reeves

A newly discovered gene variant seems to reduce an individual's fondness for alcohol, a study has found... [Read More]

China begins first CRISPR human therapy trial

21 November 2016 - by Anneesa Amjad

Chinese scientists have injected CRISPR/Cas9 gene-edited cells into a human for the first time... [Read More]

CRISPR partially restores sight in blind rats

21 November 2016 - by Paul Waldron

Scientists in the US have used a genome-editing technique to partially restore vision in blind rats... [Read More]

Podcast Review: Ethics and Genetics – Opening the Book of Life

14 November 2016 - by Rachel Siden

This podcast from the Guardian's Science Weekly series is a good introduction to the ethical questions surrounding genetic technologies... [Read More]

Therapeutic editing of the human genome – Jewish bioethical perspectives

14 November 2016 - by Dr Avi Lerner

Jewish bioethics may help to broaden the discussion of the ethical concerns that emerge from editing the human genome... [Read More]

Book Review: Redesigning Life – How Genome Editing will Transform the World

07 November 2016 - by Annabel Slater

Dr John Parrington thinks the ethics of genome editing should be shaped by scientifically informed public debate, and he hopes his book will provide a starting point... [Read More]

Podcast Review: The Primitive Streak

24 October 2016 - by Anneesa Amjad

In this podcast, Radiolab presenter Molly Webster explores the origins of the 14-day rule – the internationally agreed two-week time constraint on growing embryos in a lab... [Read More]

Gene therapy halts early Alzheimer's disease in mice

17 October 2016 - by Annabel Slater

A new gene therapy has slowed the progress of early Alzheimer's disease in mice... [Read More]

The Mexican mitochondrial fiasco

28 September 2016 - by César Palacios González

Dr John Zhang's team have opened a new door in terms of reproductive possibilities, but they may very well be instrumental in closing the assisted reproductive door for many people in Mexico... [Read More]

Study brings sickle-cell gene therapy one step closer

12 September 2016 - by Dr Nicoletta Charolidi

A genetically engineered virus that triggers the production of an alternative form of haemoglobin has reversed the symptoms of sickle cell disease in mice... [Read More]

Bioethical framework for human-animal embryo research proposed

05 September 2016 - by Anneesa Amjad

A prominent bioethicist in the USA has suggested that most of the ethical concerns surrounding the creation of animal-human chimera embryos using human pluripotent stem cells could be reasonably addressed... [Read More]

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Events using this Glossary Item

A Stroke of Genius
05 August 2009 2.40pm-3.40pm Jack Dome, Pleasance Dome, 1 Bristo Square, Edinburgh EH8 9AL, UK
A play inspired by the the true story of the Repository for Germinal Choice, a sperm bank for Nobel Prize winners...


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