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King's College London - Health: More than a medical matter

Glossary

Association

The observed connection between an inherited trait and a particular gene or DNA marker. Association studies are used to pinpoint genes involved in complex disorders which are influenced by several genetic and non-genetic factors.



Articles using this Glossary Item

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Men who smoked before teens may father fatter sons

07 April 2014 - by Kimberley Bryon-Dodd

Smoking before puberty may lead to men fathering fatter sons, suggesting that lifestyle factors can have adverse impacts on the next generation, a study has found... [Read More]

Fetal brain gene blueprint scoured for autism clues

07 April 2014 - by Dr Naqash Raja

A map showing where different genes are turned on and off in the fetal human brain has been published in the hope it will give important clues about the origins of disorders... [Read More]

Anorexia linked to genetic mutation

16 September 2013 - by Simon Hazelwood-Smith

The eating disorder anorexia nervosa has been linked, somewhat unexpectedly, to variants in a gene involved in cholesterol regulation... [Read More]

Pair of genes linked to severe childhood epilepsy

19 August 2013 - by James Brooks

Two genetic variants have been pinpointed by researchers as causing two of the most severe forms of childhood epilepsy... [Read More]

Mediterranean diet reduces stroke risk for diabetes gene carriers

19 August 2013 - by Dr Lux Fatimathas

Claims for the health benefits of the typically Mediterranean diet high in olive oil, fish, and complex carbohydrates are common, if hard to substantiate... [Read More]

Scents and sense ability: genes may influence perception of smell

05 August 2013 - by Matthew Thomas

Whether a smell strikes you as fragrant or fetid – or if you even notice it at all – may be influenced by your genes, according to a pair of studies... [Read More]

Five 'new' migraine risk genes identified

28 June 2013 - by Dr Amina Aitsi-Selmi

Five genetic regions not previously associated with migraine have been linked to the condition, according to an international group of researchers... [Read More]

Genetic find for babies born with 'hole in the heart'

03 June 2013 - by Matthew Young

A gene linked to the congenital heart disease known as 'hole in the heart' has been discovered by UK researchers.... [Read More]

Event Review: It's All in the Genes - Medical Genetics in Obstetrics and Gynaecology

28 May 2013 - by David O'Rourke

Medical genetics has changed how we think about diagnosis and treatment in almost every field of medicine. At an evening event hosted by the Royal Society of Medicine (RSM), medical genetics teamed up with obstetrics and gynaecology to explore the impact of genetics on the diagnosis of ovarian and breast cancer.... [Read More]

Consumer genetics firm 23andMe seeks regulatory approval for disease risk tests

20 August 2012 - by Ruth Saunders

23andMe, a US-based personal genomics company, has sought regulatory approval from the Food and Drug Administration for seven of its genetic tests.... [Read More]

Why the drugs don't work: gene fault explains multiple sclerosis treatment failure

23 July 2012 - by Holly Rogers

A genetic variation could explain why a previously promising class of drugs do not work as multiple sclerosis treatments despite being used successfully in other autoimmune diseases... [Read More]

Two gene variants linked to breast size also linked to breast cancer

09 July 2012 - by Ruth Saunders

Two novel gene variants linked to breast size may also also influence the risk of breast cancer, according to a study carried out by US genetics company 23andMe.... [Read More]

Lifelong intelligence isn't just down to your genes

23 January 2012 - by Linda Wijlaars

Researchers from Scotland have found around one-quarter of changes in intelligence observed from childhood to old age may be due to our genes. Although the researchers accept the finding is not statistically significant, it is the first to estimate the contribution of genetic variations to cognitive ageing.... [Read More]

First genetic link to bone marrow cancer identified

05 December 2011 - by Dr Zara Mahmoud

Two new gene variants, which each increase the risk of bone marrow cancer by 30 percent, have been identified by scientists at the Institute for Cancer Research... [Read More]

Short people 'short' on genes

28 November 2011 - by Dr Rebecca Hill

Short people can blame deleted sections of DNA for their diminutive stature, according to a study looking at variations in the genomes of over 12,000 children... [Read More]

Book Review: What's the Use of Race? Modern Governance and the Biology of Difference

21 November 2011 - by Dr Rachael Panizzo

The study of genetic diversity between ethnic groups can help explain the ways in which race influences our biology and susceptibility to disease. But what do we mean by 'race', exactly? These issues are considered in the collection of essays 'What's the use of race? Modern governance and the biology of difference', edited by Dr Ian Whitmarsh and Dr David Jones... [Read More]

Genetic regions linked to schizophrenia by two Chinese studies

07 November 2011 - by Dr Nadeem Shaikh

Two Chinese genome wide association studies (GWAS) have identified genomic regions linked to the incidence of schizophrenia. The papers, published in Nature, are some of the first GWAS to look at Chinese as opposed to Western populations.... [Read More]

Genetic variants linked to asthmatics' response to inhalers

03 October 2011 - by Luciana Strait

Inheriting two copies of a genetic variant has been associated with reduced response to steroid inhalers in people with asthma. The finding could explain why around 40 percent people with asthma do not benefit from inhaled steroids, the most commonly prescribed medication for the condition.... [Read More]

Racing ahead in the polls

26 September 2011 - by Sarah Norcross

Throughout 2011 the charity that publishes BioNews, the Progress Educational Trust, has been running a Wellcome Trust supported project entitled 'Genes, Ancestry and Racial Identity: Does It Matter Where Your Genes Come From?'. The project is now concluding with an online poll which we'd like to encourage all BioNews readers to complete... [Read More]

Blood pressure linked to genetic variations

19 September 2011 - by Dr Zara Mahmoud

Scientists have identified 29 regions of the genome associated with hypertension in people of European origin. Of these, 16 areas contained completely new genes, which had not been previously associated with the risk of developing high blood pressure.... [Read More]

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