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Preimplantation Genetic Diagnosis: The Who, the What, the Why and the How

Glossary

Association

The observed connection between an inherited trait and a particular gene or DNA marker. Association studies are used to pinpoint genes involved in complex disorders which are influenced by several genetic and non-genetic factors.



Articles using this Glossary Item

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Forty new genes linked to intelligence in humans

30 May 2017 - by Annabel Slater

A study of almost 80,000 people has identified 40 new genes linked to intelligence... [Read More]

Baldness linked to over 280 genes

20 February 2017 - by Emma Laycock

A new study has found over 280 genes associated with male-pattern baldness... [Read More]

Eight percent of tiredness linked to genes

20 February 2017 - by Dr Rosie Gilchrist

A UK Biobank study has found that genetics accounts for eight percent of the difference in people's feelings of tiredness and low energy... [Read More]

GIANT makes short work of height gene discovery

20 February 2017 - by Professor Darren Griffin

A recent large-scale study that discovered 83 rare genes related to human height reveals the power of so-called genome-wide association studies... [Read More]

New genetic links to pancreatic cancer discovered

20 February 2017 - by Jamie Rickman

Researchers have used whole-genome sequencing to uncover new mutations responsible for a rare type of pancreatic cancer... [Read More]

Twelve gene regions linked to human reproductive behaviour

07 November 2016 - by Dr James Heather

Twelve locations in the human genome have been linked with differences in reproductive behaviour... [Read More]

Crowd-sourced DNA links depression to 17 genes

08 August 2016 - by Helen Robertson

Scientists have identified 17 genetic variants that appear to be linked to depression in individuals with European ancestry... [Read More]

Ice-bucket challenge funds ALS gene discoveries

01 August 2016 - by Jenny Sharpe

Donations from the ALS 'ice-bucket challenge' have funded research that has led to the discovery of new genes linked to the disease... [Read More]

Genetic risk scores could predict Alzheimer's

11 July 2016 - by Sarah Gregory

Researchers looking at multiple genes have developed risk scores that could identify those most likely to develop Alzheimer's disease in later life... [Read More]

Video Review: What If My Neighbour's Kid Was Genetically Modified?

04 July 2016 - by Simon Hazelwood-Smith

Paul Knoepfler's TEDx talk covers familiar ground – designer babies, segregation between 'natural' and GM children, unintended side effects, playing god, and eugenics all feature in his dystopian vision of a future involving genetically modified humans... [Read More]

74 genes linked to education level, but effect is minimal

16 May 2016 - by Sophie Perry and James Brooks

One of the largest-ever genetics studies in the social sciences has found 74 genetic variants that are associated with the amount of time an individual spends in education... [Read More]

Book Review: Not In Your Genes - The Real Reasons Children Are Like Their Parents

03 May 2016 - by Dr Ross Cloney

Oliver James's new book shows little understanding of genetics, instead offering a media-friendly caricature of 'one gene = one trait', while focusing solely on parenting styles to explain human behaviour... [Read More]

Two genes linked to higher chance of having twins

03 May 2016 - by Anneesa Amjad

A study has identified two gene variants that increase the likelihood of a woman having twins and could explain why twins appears to run in families... [Read More]

Blood vessel gene linked to both stroke and dementia

11 April 2016 - by Dr Barbara Kramarz

A gene called FOXF2 has been linked to small vessel disease in the brain, a condition associated with a higher risk of stroke and dementia... [Read More]

Neanderthal DNA linked to today's diseases

22 February 2016 - by Isobel Steer

Neanderthal-derived DNA influences our risk of certain diseases, including addiction, blood clots, skin conditions and depression, a recent study has found.... [Read More]

Five new genetic regions linked to long life in humans

21 December 2015 - by Dr Ashley Cartwright

Scientists have identified five genetic loci associated with extreme longevity... [Read More]

UK Biobank data reveals new associations between smoking and lung cancer

28 September 2015 - by Antony Blackburn-Starza

Health and genetic data from the UK Biobank has revealed new genetic associations between smoking and lung cancer, including five areas of DNA for the first time associated with heavy smoking.

Obesity findings set precedent for GWAS research

07 September 2015 - by Dr James Heather

Recent findings linking the FTO gene to adipose cell energy use not only revealed a molecular mechanism that contributes to obesity, but they are also an exemplar of how genome-wide association study findings can make the journey to clinical relevance... [Read More]

Epigenetic variation predicts post-natal depression

03 August 2015 - by Dr Linda Wijlaars

Epigenetic variation can predict the risk of post-natal depression symptoms in women without a history of depression, researchers from the UK and US have found... [Read More]

Epigenetic changes linked to Alzheimer's

26 August 2014 - by Claire Downes

Researchers have identified a connection between DNA methylation and Alzheimer's disease, gaining a further understanding into the underlying causes of this neurodegenerative condition.... [Read More]

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Events using this Glossary Item

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CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

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London
8 December 2017

Speakers include

Professor Azim Surani

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Richard Anderson

Dr Sue Avery

Dr Elizabeth Garner

Professor Allan Pacey

Dr Anna Smajdor

Dr Andy Greenfield

Philippa Taylor

Dr César Palacios-González

Fiona Fox

Sarah Norcross

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