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King's College London - Health: More than a medical matter

Glossary

Epigenetics

The science of enduring (but ultimately reversible) changes in the pattern of gene activity, during embryo development and beyond, that do not involve alteration of the DNA sequence. These changes occur in response to conditions within the embryo and more generally.



Articles using this Glossary Item

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Unlocking the genetics of breast cancer

07 April 2014 - by Baroness Delyth Morgan

The news of Angelina Jolie's mastectomy last year brought breast cancer genetics, risk and prevention into the international spotlight. Her decision was only possible due to the efforts of researchers, over the past twenty years and more, to identify the inherited genetic mutations... [Read More]

Men who smoked before teens may father fatter sons

07 April 2014 - by Kimberley Bryon-Dodd

Smoking before puberty may lead to men fathering fatter sons, suggesting that lifestyle factors can have adverse impacts on the next generation, a study has found... [Read More]

Epigenetic blood test for children 'predicts' obesity five years later

31 March 2014 - by Dr Charlotte Warren-Gash

A DNA blood test for children aged five can help predict body fat levels when they are aged nine to 14, a small study suggests... [Read More]

Event Review: Bio-Revolution

17 March 2014 - by Chris Hardy

At the Science Museum's 'drinking and thinking' event, visitors extracted DNA from strawberries and discussed genome sequencing in the NHS... [Read More]

Pain sensitivity genes can be switched on or off depending on environment

10 February 2014 - by Claire Downes

Lifestyle and environmental factors can alter sensitivity to pain by switching certain genes on or off, according to research from King’s College London... [Read More]

Spotless mind: Epigenetic drug wipes clean fear memories

20 January 2014 - by Dr Katie Howe

Researchers have identified a class of drug that helps clear traumatic memories in mice. The drug may help improve the effectiveness of behavioural therapy in the treatment of post traumatic stress disorder... [Read More]

Progress Educational Trust conference: What can we learn from twins?

16 December 2013 - by Professor John Galloway

Why do we think we can learn anything useful (other than about twins themselves) from twins? It might be thought that the most important thing about them is their 'twinliness', the one attribute denied to non-twins. Science thinks otherwise... [Read More]

A whiff of fear down the generations

09 December 2013 - by Professor Marcus Pembrey

Last week saw a lot of media interest around a US study published in Nature Neuroscience reporting the transgenerational effects of fear-conditioning in mice... [Read More]

Fear can be inherited, mouse study finds

02 December 2013 - by Siobhan Chan

Mice that were conditioned to fear a specific smell passed down this fear to their offspring, suggesting that traumatic events can affect gene expression... [Read More]

Course Review: Epigenetic Control of Gene Expression

30 September 2013 - by Marco Narajos

There is definitely great scope for expansion in genetics education through online courses, but these should be tailored towards the student's pace, however leisurely that might be... [Read More]

John Lennon is dead. Long live John G2 (or not)

02 September 2013 - by Dr Dusko Ilic

I could tell straight away that Canadian dentist Michael Zuk, who invested in John Lennon's rotten molar in the hope of cloning the great musician, is a big fan of Michael Crichton's 'Jurassic Park'... [Read More]

Exercise affects epigenetics of fat storage

15 July 2013 - by Emily Hoggar

Exercise directly affects which genes are expressed or silenced, causing fat cells to function differently, according to a study in PLOS Genetics... [Read More]

Book Review: An Introduction to the Genetics and Epigenetics of Human Disease

17 June 2013 - by Holly Rogers

A beginner's tour guide through genetics and epigenetics, this booklet covers much of the fundamental biology behind genetic illness and gives a broad overview of some of the biggest challenges currently faced by researchers in the field. It does not assume any previous knowledge, and gives clear, concise summaries of key historical figures and theories, including a very useful glossary at the back.... [Read More]

Event Review: It's All in the Genes - Medical Genetics in Obstetrics and Gynaecology

28 May 2013 - by David O'Rourke

Medical genetics has changed how we think about diagnosis and treatment in almost every field of medicine. At an evening event hosted by the Royal Society of Medicine (RSM), medical genetics teamed up with obstetrics and gynaecology to explore the impact of genetics on the diagnosis of ovarian and breast cancer.... [Read More]

Early trial of epigenetic blood test for post-natal depression

28 May 2013 - by Matthew Thomas

A blood test that looks for chemical alterations to certain genes may help predict whether women will suffer post-natal depression, scientists say after a small study... [Read More]

Event Review: Genomes and Societies - Global Challenges around Life Sciences

20 May 2013 - by Chris Berry

Earlier this month, over 180 delegates and speakers gathered in London for the final annual conference of the Economic and Social Research Council (ESRC) Genomics Network (EGN). After a decade of support from the ESRC, the EGN will officially draw to a close at the end of May... [Read More]

Cancer treatment should be based on gene 'fingerprints', says study

07 May 2013 - by Suzanne Elvidge

Genetic analysis of tumours provides the key to treating them effectively, according to two studies carried out by The Cancer Genome Atlas (TCGA).... [Read More]

Autism mechanism goes beyond genes

29 April 2013 - by Dr Daniel Grimes

A study on identical twins with distinct autistic traits suggests that epigenetic factors may be important in understanding how the neurological disorder develops... [Read More]

The mother isn't always certain: Irish surrogacy case leads the way

11 March 2013 - by Dr Kirsty Horsey

Once upon a time, motherhood was certain. It was proved by giving birth. The Latin maxim 'mater semper certa est' that told us so was irrefutable. Whether or not that was ever actually true, it has for a long while been biologically, as well as socially, questionable.... [Read More]

Ireland: Genetic mother wins surrogacy case

11 March 2013 - by Ruth Retassie

The Irish High Court has ruled in a landmark case that a woman who is the genetic mother of twins born through a surrogate can be recognised as the legal mother of the children.... [Read More]

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Events using this Glossary Item

 

Epigenetics: Where Life Meets the Genome
10 November 2010 10am-5.30pm Royal Society, 6-9 Carlton House Terrace, London SW1Y 5AG, UK
The Annual Conference of the Galton Institute... [Read More]
From Imprinting to the Epigenome in 25 years
04 September 2009  Lecture Theatre, Peterhouse College, University of Cambridge, Cambridge CB2 1RD; Kings College, University of Cambridge, King's Parade, Cambridge CB2 1ST, UK
An event celebrating the discovery of imprinting in mammals 25 years ago... [Read More]


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