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The Fertility Show, Manchester Central, 24-25 March 2018

Glossary

Epigenetics

The science of enduring (but ultimately reversible) changes in the pattern of gene activity, during embryo development and beyond, that do not involve alteration of the DNA sequence. These changes occur in response to conditions within the embryo and more generally.



Articles using this Glossary Item

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Muscle memory exists on the DNA level through epigenetic tagging

05 February 2018 - by Dr Loredana Guglielmi

A study led by UK researchers has shown for the first time that human muscles possess a 'memory' of earlier growth... [Read More]

What's a bit of genetic interplay between friends?

29 January 2018 - by Professor Marcus Pembrey

The recent demonstration that friends share more of their genetic makeup in common than two people picked at random from their population has been making the headlines... [Read More]

Creating life in the lab: in vitro gametogenesis (IVG) and synthetic human entities with embryo-like features (SHEEFs)

08 January 2018 - by Dr Jess Buxton

What exactly are SHEEFs and IVGs? How might they shed light on the mysteries of early embryo development, and offer new hope to those affected by infertility? These questions were the focus of the second session at Progress Educational Trust's one-day conference 'Crossing Frontiers: Moving the Boundaries of Human Reproduction' in London on 8 December 2017... [Read More]

New CRISPR technique reverses diabetes and kidney failure in mice without cutting DNA

11 December 2017 - by Isobel Steer

Scientists in California have used a modified form of the CRISPR/Cas9 genome editing approach to epigenetically treat diabetes, kidney disease and muscular dystrophy in mice... [Read More]

Radio Review: PM - Our Fertility Journey

11 December 2017 - by Eleanor Taylor

Despite concerted efforts to reduce the stigma surrounding fertility struggles, there still appears to be a 'facelessness' to this incredibly common issue, which suggests that fertility is still very much a taboo subject... [Read More]

Autism, genetics and epigenetics: why the lived experience matters in research

04 December 2017 - by Dr Kristien Hens and Dr Leni Van Goidsenhoven

Popular scientific publications regularly have articles with headlines suggesting that 'autism is hereditary' or that the 'risk for developing autism' is mostly caused by genetics... [Read More]

Epigenetics of addiction relapse probed using rats

02 October 2017 - by Annabel Slater

Researchers have identified how the likelihood of cocaine addiction relapse is influenced by epigenetic changes in rats... [Read More]

Book Review: How to Code a Human

18 September 2017 - by Mikey Lebrett

Genomics may herald a bright future - for those who understand it. But what about those who do not? Dr Kat Arney's new book 'How to Code a Human' is a beautiful example of how complicated genetic topics can be simplified and clarified to make them understandable and enjoyable for the least-scientific of readers.... [Read More]

Environmental chemicals affect sperm epigenetics

18 September 2017 - by Dr Kimberley Bryon-Dodd

A type of chemical found in various personal beauty products and plastics may affect sperm and lower reproductive success, according to a new study... [Read More]

Deficient diet linked to schizophrenia symptoms in mice

11 September 2017 - by Annabel Slater

Mice deprived of two essential fatty acids during pregnancy give birth to pups with schizophrenia-like symptoms... [Read More]

Podcast Review: Editing the Embryo - removing harmful gene mutations

04 September 2017 - by Eleanor Taylor

As a scientist working in a fertility clinic, my normal everyday work routine is occasionally punctuated by the ripple effect that occurs when reports of a new groundbreaking reproductive technology enters the public consciousness. I am soon inundated with questions... [Read More]

New gene silencing method discovered

24 July 2017 - by Helen Robertson

US scientists have identified a new mechanism by which genes are silenced, or 'imprinted' during early embryonic development... [Read More]

Older fathers may have less success with IVF

03 July 2017 - by Shaoni Bhattacharya

The success of IVF in women under the age of 40 may be affected by the age of their male partners, suggests a US study... [Read More]

Drinking tea alters women's epigenetics

05 June 2017 - by Cara Foley

Researchers have found that drinking tea may affect gene expression in women... [Read More]

Radio Review: The Secrets Inside Your Cells - Epigenetics, Trauma and Ancestry

08 May 2017 - by Dr Avi Lerner

The Human Genome Project, completed in April 2003, greatly improved our ability to study human health and disease. It also provided a deeper insight into our history and evolution as a species. Yet a recent episode of the 'Science Friction' radio show, presented by Natasha Mitchell on Australia’s ABC Radio, delved further into these fascinating topics through the lens of the new and emerging field of epigenetics.

Autism linked to grandmothers' smoking

02 May 2017 - by Annabel Slater

A higher likelihood of autism spectrum disorder and autistic traits have been linked to maternal grandmothers smoking while pregnant... [Read More]

Babies born through IVF have higher cancer rates

02 May 2017 - by Dr Rachel Brown

Children born through IVF are at an increased risk of some childhood cancers, suggests a new study... [Read More]

Book Review: Introducing Epigenetics - A Graphic Guide

27 February 2017 - by Annabel Slater

'Introducing Epigenetics: A graphic guide' is a mini-textbook pitched as a non-fiction comic book. Despite the colourful cover and perky graphics inside, this book does not make for light reading... [Read More]

ACMG recommends caution on genome editing

06 February 2017 - by Rachel Siden

The American College of Medical Genetics and Genomics has published a statement recommending caution over the clinical application of genome editing... [Read More]

Gene therapy 'reverses ageing' in mice

19 December 2016 - by Sarah Gregory

Gene therapy can reverse the effects of ageing in mice, researchers claim... [Read More]

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Events using this Glossary Item

Epigenetics: Where Life Meets the Genome
10 November 2010 10am-5.30pm Royal Society, 6-9 Carlton House Terrace, London SW1Y 5AG, UK
The Annual Conference of the Galton Institute...
From Imprinting to the Epigenome in 25 years
04 September 2009  Lecture Theatre, Peterhouse College, University of Cambridge, Cambridge CB2 1RD; Kings College, University of Cambridge, King's Parade, Cambridge CB2 1ST, UK
An event celebrating the discovery of imprinting in mammals 25 years ago...


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