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Glossary

Personalised/precision/stratified medicine

An approach to medicine based on grouping patients according to the characteristics of their disease or how they respond to particular treatments (or to prophylaxis). This enables the identification and development of measures that are most effective for particular groups of patients.



Articles using this Glossary Item

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BRCA screening could prevent 1000 cases of breast cancer a year

13 November 2017 - by Dr Loredana Guglielmi

Researchers have introduced new criteria to screen for BRCA gene mutations that could prevent more than 10,000 cases of cancer and save more than 2000 lives in the next decade... [Read More]

Number of mutations needed to cause cancer calculated

19 October 2017 - by Charlott Repschlager

Between one and 10 mutations are required for a healthy cell to turn cancerous... [Read More]

Child brain cancer redefined as 10 different diseases

02 October 2017 - by Dr Molly Godfrey

Deadly childhood brain tumours are highly diverse and can be divided into 10 different subtypes, according to new research... [Read More]

Cancer mutations explored using organoids and CRISPR

18 September 2017 - by Dr Molly Godfrey

Organoids and CRISPR/Cas9 have been combined in a novel method to study genetic mutations occurring in cancer... [Read More]

Gene therapy for cancer halted after patient death

11 September 2017 - by Ebtehal Moussa

Two trials assessing gene therapy for blood cancer have been put on hold by the US Food and Drug Administration, following a patient fatality... [Read More]

Cancer atlas leads way to personalised treatment

21 August 2017 - by Marcia Costa

Genes linked to 17 types of cancer have been mapped in a new Pathology Atlas by Swedish researchers... [Read More]

Supercomputer overcomes key cancer genomics bottleneck

31 July 2017 - by Rikita Patel

The IBM Watson supercomputer can analyse 160 hours' worth of genomic data in just ten minutes... [Read More]

South Asian social systems give insight into genetics

24 July 2017 - by Charlotte Spicer

Genome-wide analysis in South Asian populations may provide insight into rare genetic diseases, suggests research... [Read More]

First personalised vaccines shows promise for skin cancer

10 July 2017 - by Meetal Solanki

A revolutionary vaccine uses the patient’s own immune response to target tumour cells and could be the first step in bespoke, precision medicine. 

Generation Genome - sequencing is future for NHS, says report

10 July 2017 - by Jennifer Willows

The Chief Medical Officer of England's annual report has recommended that personalised medicine approaches be adopted widely within the NHS.

What next for genomics? Providing answers, changing lives, transforming the NHS

10 July 2017 - by Dr Rachel Brown

A packed public event, produced by the Progress Educational Trust in partnership with Genomics England, saw the Chief Medical Officer for England launch her report 'Generation Genome'... [Read More]

Liquid biopsy may help target prostate cancer treatment

26 June 2017 - by Charlotte Spicer

A new three-in-one blood test could progress personalised treatment for patients with prostate cancer... [Read More]

Ovarian cancer drug could treat BRCA-related breast cancer

12 June 2017 - by Dr Loredana Guglielmi

A drug treatment for ovarian cancer has shown success against inherited breast cancer... [Read More]

Two blood cancers treated successfully with immunotherapy

12 June 2017 - by Ebtehal Moussa

Two trials of a new gene therapy have successfully treated blood cancers in patients who were unresponsive to standard treatment... [Read More]

FDA gives go-ahead to first cancer drug based on genetics

30 May 2017 - by Shaoni Bhattacharya

The first cancer drug based on a specific genetic feature has been approved by the US drugs regulator... [Read More]

If you could alter the characteristics of future generations, would you do it?

22 May 2017 - by Dr Peter Mills

The Nuffield Council on Bioethics is seeking views on the reproductive uses of genome editing in humans. Regular readers of BioNews will know that genome editing (including with the CRISPR-Cas9 technique) offers a way of making precisely targeted modifications to DNA in living cells, harnessing the cells’ inbuilt repair mechanisms to repair a deliberate, double-stranded DNA break in a way that may either disable or introduce a functional DNA sequence... [Read More]

Gene may accelerate memory loss in Alzheimer's disease

08 May 2017 - by Lone Hørlyck

A gene mutation may speed up memory loss and general cognitive decline in people who are at risk of developing Alzheimer’s disease... [Read More]

FDA approves home genetic tests for 10 diseases

10 April 2017 - by Jamie Rickman

The US Food and Drug Administration has approved the first genetic test to estimate an individual's risk of disease that can be sold directly to consumers... [Read More]

Podcast Review: Naked Genetics – Testing, testing

06 March 2017 - by Matthew Thomas

Dr Kat Arney leads a fascinating and wide-ranging discussion of genetic testing – from testing for cancer genes to whether your child's DNA can predict their future sporting ability... [Read More]

Discussion of ethics of new IVG technique is needed, say US experts

16 January 2017 - by Annabel Slater

Three US experts say public conversation should begin now on the ethical challenges raised by a new fertility technology that could reprogram any human cell into eggs and sperm... [Read More]

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Events using this Glossary Item

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Published by the Progress Educational Trust

CROSSING FRONTIERS

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Andy Greenfield

Dr Anna Smajdor

Dr Henry Malter

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross

Sandy Starr


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