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Glossary

BRCA1

A gene on chromosome 17, which instructs the cell to make a protein that normally helps to repair damaged DNA and suppress cell growth. A person who inherits certain mutations in a BRCA1 gene has a higher risk of getting breast cancer and certain other types of cancer.



Articles using this Glossary Item

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BRCA gene does not affect survival in those treated for breast cancer

15 January 2018 - by Hannah Somers

A new study has found that BRCA gene mutations do not affect the survival rates of breast cancer patients under 40... [Read More]

Seventy-two new gene targets for breast cancer found

30 October 2017 - by Annabel Slater

Two studies have discovered 72 new genetic variants associated with the risk of developing breast cancer... [Read More]

Gene test could improve prediction of breast cancer risk

16 October 2017 - by Hannah Somers

A new genetic test to accurately predict an individual's risk of developing breast cancer will soon be rolled out at two hospital clinics in Manchester... [Read More]

Researchers crack how BRCA1 gene raises cancer risk

09 October 2017 - by Dr Loredana Guglielmi

A major breakthrough in understanding how mutations in the BRCA1 gene raise cancer risk has been made by researchers in the USA... [Read More]

Lifetime cancer risk predicted for BRCA mutation carriers

26 June 2017 - by Lea Goetz

A study of almost 10,000 women carrying BRCA mutations has revealed the best estimate yet of their risk in developing breast and ovarian cancer... [Read More]

Liquid biopsy may help target prostate cancer treatment

26 June 2017 - by Charlotte Spicer

A new three-in-one blood test could progress personalised treatment for patients with prostate cancer... [Read More]

Ovarian cancer drug could treat BRCA-related breast cancer

12 June 2017 - by Dr Loredana Guglielmi

A drug treatment for ovarian cancer has shown success against inherited breast cancer... [Read More]

Existing drugs could benefit one in five breast cancer patients

20 March 2017 - by Dr Molly Godfrey

A genetic study of breast cancer patients suggests that existing drugs for treating rare breast and ovarian cancers may help more patients than previously thought... [Read More]

BRCA testing not offered to enough high-risk patients

13 February 2017 - by Hannah Somers

A study has indicated that US doctors may not be recommending genetic testing to a sufficient number of high-risk breast cancer patients... [Read More]

More women get tested for breast cancer genes thanks to 'Angelina Jolie effect'

19 December 2016 - by Anastassia Bolotkova

Angelina Jolie's 2013 public announcement that she has the BRCA1</i> breast cancer gene led to a 64 percent increase in women seeking genetic testing for breast cancer... [Read More]

Event Review: Who owns your genome?

03 October 2016 - by Isobel Steer

Do you know who owns your genome? And who, if anyone, would you choose to give your genetic information to? This debate, organised by the British Science Association and supported by Genomics England, covered the cutting-edge issues in genomic ethics and legality... [Read More]

FDA warns against ovarian cancer screening tests

12 September 2016 - by Anastassia Bolotkova

The FDA has warned that it does not recommend the use of any currently available ovarian cancer screening tests to detect the disease... [Read More]

Quick and cheap DNA tests for ovarian cancer patients 'would save lives'

18 July 2016 - by Hannah Somers

Researchers have developed a new pathway for genetically testing ovarian cancer patients which they say will save both lives and money... [Read More]

BRCA mutations linked to prostate and uterine cancers

11 July 2016 - by Antony Blackburn-Starza

Genetic mutations on several genes including BRCA2 have been associated with prostate cancer; while in a separate study, a BRCA1 mutation has been linked to a particular form of uterine cancer... [Read More]

Osteoporosis drug touted as potential 'BRCA-blocker'

27 June 2016 - by Helen Robertson

A drug currently used to treat osteoporosis in old age may help prevent breast cancer in women with a genetic predisposition for the disease... [Read More]

BRCA database now holds data on 6200 variants

06 June 2016 - by Dr James Heather

After one year of existence, the BRCA Share database has released details on its progress in collating information on variants of the BRCA1 and BRCA2 genes... [Read More]

Myriad: Patients seek right to access personal genetic information

23 May 2016 - by Antony Blackburn-Starza

Myriad Genetics has been hit by a complaint filed by the American Civil Liberties Union (ACLU) on behalf of four patients who are seeking a right of access to all their genetic information held by the company... [Read More]

No benefit from expanding cancer-risk gene test beyond the essentials

09 May 2016 - by Rachel Siden

Adding more genes to existing multi-gene panels that test for breast and ovarian cancer risk offers little clinical benefit, a study says... [Read More]

BRCA1 mutation linked to reduced egg reserves

25 April 2016 - by Dr Katie Howe

Women with a mutation in the breast-cancer susceptibility gene BRCA1 may have reduced numbers of eggs left in their ovaries, according to a study led by Australian scientists... [Read More]

Genetics company launches huge open-access database

14 March 2016 - by Isobel Steer

Genetic-testing company Ambry Genetics has launched a huge database of cancer-patient genetics, freely available to the public... [Read More]

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