Subscribe to the BioNews newsletter for free

Login
Advanced Search

Search for
BioNews

Like the Progress Educational Trust on Facebook



 

Companies hold patents on entire human genome

08 April 2013

By Ruth Saunders

Appeared in BioNews 699

A new study has reported that the entire human genome may be under patents held by commercial companies.

The report, published in the journal Genome Medicine, says that 41 percent of the human genome is currently subject to patents on 'long' DNA sequences and many patents over 'short' sequences have the aggregate potential to cover the whole of the human genome.

It concludes that with over 40,000 patents granted on DNA molecules, companies have made a claim to the entire human genome for commercial profit. 'If these patents are enforced, our genomic liberty is lost', said lead author Dr Christopher Mason of Weill Cornell Medical College, New York.

On 15 April 2013, the US Supreme Court will review the right of Myriad Genetics to claim patents not only on two key breast and ovarian cancer genes—BRCA1 and BRCA2—but also on any short sequences within BRCA1. Many of these short sequences are linked to other cancers, as well as genes involved in brain development and heart function.

'This means if the Supreme Court upholds the current scope of the patents, no physician or researcher can study the DNA of these genes from their patients, and no diagnostic test or drug can be developed based on any of these genes without infringing a patent', said Dr Mason, in a statement to Nature World News.

The impact of patents is onerous on researchers. 'Almost every day, I come across a gene that is patented—a situation that is common for every geneticist in every lab', Dr Mason told GenNews.

Dr Mason and his team examined the structure of the human genome and analysed both short and long fragments of DNA sequences. They found that every short fragment in the human genome matched at least one other gene. If all of the patents on short sequences were allowed in aggregate, they would cover virtually the entire genome.

'This demonstrates that short patent sequences are extremely nonspecific and one gene will always cross-match and patent a portion of another gene as well', says Dr Mason. 'This means it is actually impossible to have a patent for just one gene'.

Dr Mason describes this as 'patently ridiculous'. 

'I believe that individuals have an innate right to their own genome, or to allow their doctor to look at that genome, just like the lungs or kidneys', Dr Mason told GenNews.

'Failure to resolve these ambiguities perpetuates a direct threat to genomic liberty, or the right to one's own DNA'.

SOURCES & REFERENCES
Nature World News | 27 March 2013
 
Genome Medicine | 28 March 2013
 
Genetic Engineering & Biotechnology News | 27 March 2013
 
Weill Cornell Medical College (press release) | 25 March 2013
 

RELATED ARTICLES FROM THE BIONEWS ARCHIVE

15 July 2013 - by Ruth Retassie 
Myriad Genetics is suing two other companies who are offering genetic tests for BRCA1 and BRAC2 gene mutations for patent infringement...
01 July 2013 - by Dr Michael Hopkins and Dr Stuart Hogarth 
Last week saw the conclusion of the long-running gene patent lawsuit known as AMP v. Myriad Genetics. At stake was the patentability of isolated DNA sequences...
24 June 2013 - by Dr Linda Briceno Moraia and Dr Jane Kaye 
The US Supreme Court decision in Association for Molecular Pathology v. Myriad Genetics will have far-reaching implications, not just by lowering the costs of genetic tests, but also for the development of innovations in genetics and genomics and in other emerging fields such as stem cell research and synthetic biology....
17 June 2013 - by Dr Sarah Spain 
The US Supreme Court has unanimously rejected a number of patent claims made by Myriad Genetics on isolated forms of two genes, BRCA1 and BRCA2, associated with an increased risk of breast and ovarian cancer....
03 June 2013 - by BioNews 
A patent over a method for assessing cell-cycle data that can be used in IVF treatments to predict an embryo's future viability will make IVF treatments in the USA prohibitively expensive, a leading embryologist has said...

18 February 2013 - by Matthew Thomas 
A patent over a gene linked to hereditary breast and ovarian cancers is valid, an Australian federal court has ruled in a landmark case....
03 December 2012 - by Antony Blackburn-Starza 
The German Federal Court of Justice has ruled that a disputed patent held by Dr Oliver Brüstle, and the subject of a ruling by the European Court of Justice (ECJ) against the patentability of human embryonic stem cells, is valid in its revised form....
01 October 2012 - by Ruth Saunders 
The American Civil Liberties Union has asked the US Supreme Court to reconsider its decision to uphold the patent held by Myriad Genetics on two human genes associated with hereditary breast and ovarian cancers...
20 August 2012 - by Dr Sarah Spain 
In the latest instalment of a highly contested case, the US Federal Circuit Court of Appeals in Washington DC upheld Myriad Genetics' right to patent two genes, BRCA1 and BRCA2,which are associated with the risk of breast and ovarian cancer....

HAVE YOUR SAY
Be the first to have your say.

You need to or  to add comments.

By posting a comment you agree to abide by the BioNews terms and conditions


- click here to enquire about using this story.

Published by the Progress Educational Trust

CROSSING FRONTIERS

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Andy Greenfield

Dr Anna Smajdor

Dr Henry Malter

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross

Sandy Starr


BOOK HERE

Good Fundraising Code

Become a Friend of PET HERE and give the Progress Educational Trust a regular donation