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King's College London - Health: More than a medical matter

Glossary

SCNT (somatic cell nuclear transfer)

SCNT (somatic cell nuclear transfer) is a technique in which the genetic material from an egg cell is replaced with that of an adult or embryo body cell of the same animal species. Also known as cell nucleus replacement (CNR), or popularly as 'cloning'.



Articles using this Glossary Item

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Embryonic stem cell production breakthrough achieved in mice

31 March 2014 - by Dr Lanay Tierney

A technique to generate mouse embryonic stem cells could, if repeated in human cells, improve access to stem cells by using fertilised eggs that would previously have been discarded... [Read More]

Human embryonic stem cell study under investigation

28 May 2013 - by Richard Fadok

A group of anonymous scientists has voiced concerns about a controversial stem cell finding published online in Cell earlier this month, causing the journal to begin an investigation... [Read More]

Human embryonic stem cells created via cloning

20 May 2013 - by Dr Rosie Morley

Embryonic stem cells have been created from human skin cells for the first time by US scientists using a cloning technique... [Read More]

Crick Cambridge college commemoration

29 April 2013 - by Purvi Shah

A memorial to Francis Crick has been unveiled at his former college at the University of Cambridge to mark the 60th anniversary of the publication of the structure of DNA... [Read More]

Professors Gurdon and Yamanaka awarded Nobel Prize for work on stem cells

08 October 2012 - by Antony Blackburn-Starza

Professor Sir John Gurdon of the University of Cambridge has been jointly awarded the Nobel Prize for his work on stem cells. He shares the prize for medicine or physiology with Professor Shinya Yamanaka from Japan... [Read More]

Breakthrough in stem cell research - world's first reprogrammed adult cell

10 October 2011 - by Dr Louisa Petchey

US scientists have for the first time created 'personalised' human embryonic stem cells (hESCs) using a form of cloning. The result is a significant milestone on the route to using stem cell-based therapies but the researchers stress more work is to be done as genetic errors in the cells means they are not yet suitable for therapeutic use.... [Read More]

HFEA asks scientists for advice on mitochondrial disease treatment

14 March 2011 - by MacKenna Roberts

Health Secretary, Andrew Lansley has asked the Human Fertilisation and Embryology Authority (HFEA) to convene an expert group 'to assess the effectiveness and safety' of a fertility treatment that would enable children to be born without potentially devastating, incurable mitochondrial diseases.

Study war no more: Science, politics and the battle over US government funding for embryonic stem cell research

13 September 2010 - by Dr Megan Allyse

Have you ever played the children's game Red Light/Green Light? Someone yells 'green light!' and everyone runs as fast as they can (some in circles, but that's not against the rules). When they yell 'red light!', everyone freezes in some contorted position. Playing Red Light/Green Light seems not unlike the experience of conducting embryonic stem cell research in the United States... [Read More]

Setback in non-embryonic stem cell use

02 August 2010 - by Dr Rachael Panizzo

Stem cells created from a patients' own tissue are subtly different from those derived from embryos in ways that may affect their therapeutic potential, two independent research groups have found. Both studies found induced pluripotent stem cells (iPS) retain an 'epigenetic memory' of their tissue of origin... [Read More]

Book Review: An Introduction to Stem Cells

06 January 2010 - by Dr Karen Devine

With modern day medico-scientific technology advancing at an incredible pace, it is very easy for the layperson to become caught up in the technical language used by scientists and academics in their specialist field. Often, out of a lack of expertise, even the media misrepresent information, particularly in relation to research involving stem cells... [Read More]

New rules allow federal funding of US stem cell lines

09 July 2009 - by Ben Jones

The US National Institutes of Health (NIH) has published new rules that will govern state funded embryonic stem (ES) cell research now that the seven years of restriction under the Bush administration have come to an end. The new rules restrict research to stem cells sourced from surplus embryos donated by IVF patients and, consequently, forbid research on any embryo that was created specifically for the purposes of research (either through voluntary donation of human eggs or by employing... [Read More]

Day-glow dogs for genetic research

05 May 2009 - by Adam Fletcher

Researchers in South Korea have announced the creation of four healthy puppies that glow bright red under UV light. Reported in the journal Genesis, the team from the College of Veterinary Medicine at Seoul National University claim the new model will be of importance in the study... [Read More]

Obama victory heralds change in US stem cell policy

10 November 2008 - by Antony Blackburn-Starza

President-elect Barack Obama's victory in last week's US presidential elections is being celebrated by supporters of embryonic stem (ES) cell research. Senator Obama has been a vocal advocate of removing the current restriction on federal funds for human ES cell research imposed by President Bush in 2001... [Read More]

Mice cloned from frozen brain cells

09 November 2008 - by Lorna Stewart

A team of scientists from the Riken Centre for Developmental Biology in Kobe, Japan have cloned healthy mice from the cells of animals frozen 16 years ago. The technique they used involved taking the nucleus of a cell from a frozen mouse and injecting it into a... [Read More]

'Egg sharing' and 'hybrid embryos' offer hope for stem cell research

07 July 2008 - by Dr Rebecca Robey

Two announcements made last week have important implications for the future progress of human stem cell research in the UK. Both were related to research involving 'therapeutic cloning' - the creation of stem cell lines from patients with incurable diseases (such as Alzheimer's and cardiomyopathy) in order to... [Read More]

Stem cell researchers warn of egg shortage in the US

22 June 2008 - by Antony Blackburn-Starza

US stem cell researchers have called for prohibitions on the payment of compensation to egg donors to be removed if an egg shortage crisis is to be avoided. In an article published in Nature last week, Kevin Eggan and Douglas Melton from Harvard University's Stem Cell Institute... [Read More]

Australian researchers apply for a licence to create cloned human embryos

09 June 2008 - by Antony Blackburn-Starza

Two teams of Australian scientists have applied for a licence to use eggs left over from fertility treatment to create cloned human embryos, Australian newspapers report. The application, which is the first to be made in the country, has been submitted to a National Health and Medical... [Read More]

Western Australia rejects cloning legislation

12 May 2008 - by Antony Blackburn-Starza

The Upper House of the state of Western Australia has voted against legislation to permit the cloning of human embryos for research and to also allow surplus embryos to be donated for medical research following IVF. The bill, which if passed would have brought the state in... [Read More]

Ohio considers anti-cloning measure

06 May 2008 - by Antony Blackburn-Starza

A measure which if passed will ban all forms of embryo cloning in the state of Ohio, including somatic cell nuclear transfer or so-called 'therapeutic cloning', is currently being debated by the Ohio Senate Judiciary Civil Justice Committee. The Committee has not yet voted on Senate Bill... [Read More]

Campaigners call for parental consent in stem cell research

04 February 2008 - by Katy Sinclair

Campaigners are lobbying the UK Government to change the current Human Fertilisation and Embryology Bill to allow embryonic stem cells to be created using tissue from ill children, in order to facilitate research into life-limiting diseases. Under the current version of the Bill the procedure could not... [Read More]

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