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The Fertility Show

Glossary

Aneuploidy

An abnormal number of chromosomes, either too few or too many. Nearly all human body cells usually have a set of 46 chromosomes, while egg and sperm cells have 23.



Articles using this Glossary Item

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Older eggs less fertile due to poor cell division

10 April 2017 - by Emma Laycock

Researchers in Canada have found that age-related infertility may be due to older eggs dividing poorly, leading to errors in chromosome number... [Read More]

Mitochondrial replacement therapy and the welfare of the child

17 October 2016 - by Dr Mair Crouch

The announcement of the birth of the first child conceived using mitochondrial donation was unforeseen. Nonetheless, in any country regulation should be required to protect the interests of the child... [Read More]

Testing, Testing 1, 2, 3: PGS and PGD

26 September 2016 - by Dr Nicoletta Charolidi

There was a captivating debate around the emerging genetic choices, legal framework and ethical issues from the use of PGS (pre-implantation genetic screening) and PGD (pre-implantation genetic diagnosis) at this event produced by the Progress Educational Trust (PET)... [Read More]

Gene involved in egg and sperm production linked to Down's syndrome

15 August 2016 - by Dr Katie Howe

Researchers have identified an enzyme that helps ensure egg and sperm cells contain the right number of chromosomes... [Read More]

Event Review: Genetic Screening and Respect for Persons

18 July 2016 - by Amina Yonis

Non-invasive prenatal testing (NIPT) is improving all the time, and the tests may soon be offered to all pregnant women on the NHS. This event explored how to ensure that prospective mothers are properly counselled to make informed decisions about their pregnancy... [Read More]

ESHRE 2016: Research highlights

11 July 2016 - by Ayala Ochert

A roundup of research stories from the annual meeting European Society of Human Reproduction and Embryology that hit the headlines this week... [Read More]

IVF: the next generation – first UK baby born after DNA screening technique

09 May 2016 - by James Brooks

The UK's first baby resulting from an embryo that was screened using next-generation DNA sequencing has been born in Oxford... [Read More]

Reassurance for mothers over mosaic aneuploidy in CVS

03 May 2016 - by Professor Magdalena Zernicka-Goetz

Although our recent findings on the fate of aneuploid cells in mosaic embryos have indeed been somewhat misrepresented in the press, our findings may still constitute a strand of hope for mothers who have had early test results showing mosaic aneuploidy... [Read More]

Abnormal fetuses are highly unlikely to heal themselves

18 April 2016 - by Professor Caroline Ogilvie

Press coverage of a recent study on mouse embryos speculates that termination of human pregnancies diagnosed with aneuploidy (a family of conditions including Down's syndrome) at prenatal diagnosis could be unnecessary, due to the ability of the fetus to 'heal itself'. In fact, the paper's findings are not relevant to aneuploidy detected at prenatal diagnosis... [Read More]

Mouse study raises debate over embryo viability testing

04 April 2016 - by Helen Robertson

The presence of genetic abnormalities in cells taken from the placenta at the early stages of pregnancy does not necessarily mean that a baby will be born with a genetic disorder, a study in mice suggests.... [Read More]

Reply to the signatories of the COGEN Consensus Statement

21 March 2016 - by Heidi Mertes, Sjoerd Repping & Guido de Wert

The cosignatories of the COGEN consensus statement attempt to refute our remarks and concerns about the increased use of preimplantation genetic screening by presenting the same low-level 'evidence' they continuously use to advocate the widespread adoption of PGS... [Read More]

Reply to Mertes, Repping and de Wert 'Stating the obvious: discarding embryos does not increase your chance of having a baby'

22 February 2016 - by The signatories of the COGEN Consensus Statement

It is clear from the reply of Mertes et al in BioNews 835 to the COGEN Consensus Statement on preimplanation genetic screening that some controversy still remains regarding the benefits of PGS... [Read More]

Stating the obvious: discarding embryos does not increase your chance of having a baby

18 January 2016 - by Heidi Mertes, Sjoerd Repping & Guido de Wert

Under the auspices of the Virtual Academy of Genetics, COGEN recently issued a 'consensus statement' on preimplantation genetic screening, based on a scientific meeting held in Paris last September... [Read More]

Mitochondrial DNA test improves IVF success rates

26 October 2015 - by Jessica Richardson

A test which measures mitochondrial DNA levels in the embryo could help increase IVF success rates, scientists claim... [Read More]

Prenatal test detects cancer in mothers

20 July 2015 - by Ceri Durham

Abnormal results from a non-invasive prenatal test for fetal chromosome abnormality may indicate the presence of previously undetected cancers in some mothers.... [Read More]

Non-invasive prenatal testing for Down's syndrome - beyond the hype

22 June 2015 - by Jane Fisher

There has been much recent media interest in non-invasive prenatal testing for Down's syndrome, and this coincides with deliberations by the UK National Screening Committee on its potential inclusion in the NHS Down's syndrome screening programme... [Read More]

Down's syndrome blood test more accurate than existing screening

13 April 2015 - by Kirsty Oswald

Research shows that a new prenatal blood test for Down's syndrome outperforms current methods of screening... [Read More]

We are what our mothers eat

28 April 2014 - by Professor Tom Fleming

Increasing evidence, mainly from animal studies, suggests that eggs and very early embryos in the first few days after conception can be particularly sensitive to their environment with lifetime consequences including risk of diseases into adulthood... [Read More]

Experts back maternal blood test for Down's syndrome

10 March 2014 - by Dr Victoria Burchell

A test using a simple blood sample from the expectant mother should soon be the primary screening method for Down's syndrome, according to a report from the Royal College of Obstetricians and Gynaecologists (RCOG)... [Read More]

First baby born from 'cheaper' gene sequencing of IVF embryos

08 July 2013 - by Siobhan Chan

A 'powerful' form of genome analysis could improve embryo selection for IVF, according to scientists who report that the first baby has been born from this method... [Read More]

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Events using this Glossary Item

Testing, Testing 1, 2, 3: PGS and PGD
13 September 2016 6pm (registration), 6.30pm-8.30pm (discussion) Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH
The Progress Educational Trust's FREE-to-attend event about testing and screening human embryos is taking place TOMORROW EVENING - book NOW. The event will be chaired by Dr Sue Avery, with speakers including Dr Tony Gordon, Dr Christine Patch, James Lawford Davies and Professor Michael Parker...


Published by the Progress Educational Trust

CROSSING FRONTIERS

Moving the Boundaries of Human Reproduction

Public Conference
London
8 December 2017

Speakers include

Professor Azim Surani

Professor Magdalena Zernicka-Goetz

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Allan Pacey

Dr Sue Avery

Professor Richard Anderson

Dr Elizabeth Garner

Dr Jacques Cohen

Dr Anna Smajdor

Dr Andy Greenfield

Vivienne Parry

Dr Helen O'Neill

Dr César Palacios-González

Philippa Taylor

Fiona Fox

Sarah Norcross


BOOK HERE

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