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The Fertility Show, Manchester Central, 24-25 March 2018



The single cell formed immediately after fertilisation, once the genetic information of the egg and sperm have fused.

Articles using this Glossary Item


First genome editing of human embryos by UK scientists

25 September 2017 - by Paul Waldron

UK scientists have successfully edited the genome of human embryos to study the role of a gene key to the earliest stages of development... [Read More]

Mitochondrial replacement therapies in Mexico and the USA - and the FDA

29 August 2017 - by Dr César Palacios-González

Almost a year after the first live birth of a baby following a mitochondrial replacement technique procedure, the US Food and Drug Administration has sent a very strongly-worded letter to the scientist and team responsible for the event... [Read More]

Stem cells reprogrammed to resemble fertilised eggs

23 January 2017 - by Dr Loredana Guglielmi

Researchers have successfully turned stem cells into 'totipotent' cells, with characteristics resembling those of fertilised eggs... [Read More]

Book Review: GMO Sapiens - The Life-Changing Science of Designer Babies

30 August 2016 - by Julian Hitchcock

GMO Sapiens is just the annoying grit in the machine that the genome editing debate needs, but readers deserve clearer lines between science, speculation and opinion... [Read More]

Mitochondrial donation case study finally published after 13 years

22 August 2016 - by Dr Özge Özkaya

Chinese researchers say an IVF technique called pronuclear transfer can safely produce a viable pregnancy... [Read More]

Culturing a human embryo for 14 days – what have we learned?

16 May 2016 - by Dr Helen O'Neill

Species-specific differences in terms of developmental timing and molecular expression patterns have restricted our true understanding of early human development... [Read More]

Gene editing of human embryos – more ethical questions to answer

11 May 2015 - by Dr Calum MacKellar

The short article by Robin Lovell-Badge entitled 'Editing human embryos' addressing the work of Junjiu Huang and colleagues in China on gene editing in human embryos - such as the use of the CRISPR/Cas9 system - raises a number of ethical questions.... [Read More]

Event Review: It's All in the Genes - Medical Genetics in Obstetrics and Gynaecology

28 May 2013 - by David O'Rourke

Medical genetics has changed how we think about diagnosis and treatment in almost every field of medicine. At an evening event hosted by the Royal Society of Medicine (RSM), medical genetics teamed up with obstetrics and gynaecology to explore the impact of genetics on the diagnosis of ovarian and breast cancer.... [Read More]

Preventing transmission of mitochondrial DNA disease: new developments

19 November 2012 - by Professor Mary Herbert

The energy required for our cells to function properly is mainly produced by mitochondria. Mitochondria are tiny structures within our cells, which contain their own DNA. The mitochondrial DNA (mtDNA) encodes a small number of the many proteins required to produce energy efficiently. Mutations in mtDNA cause a broad spectrum of diseases and degenerative disorders, which can be fatal.... [Read More]

Transferring single embryos: Education ain't enough

23 May 2011 - by Dr Alan Thornhill

When asked why having twins isn't a good idea, I struggle. I start trotting out the party line, the obstetric risks and risks to the babies themselves, and then begin to shuffle my feet. It's complicated, I say, hoping they will move onto another topic... [Read More]

New mathematical framework for identifying healthiest IVF embryos

02 March 2009 - by Dr Will Fletcher

Researchers from the University of the Basque Country (UPV-EHU) have developed a new mathematical classification scheme that can be used to select embryos for use in assisted reproduction treatments. The Spanish scientists presented this 'intelligent system' of support for infertility treatments in the journal Computer Methods and... [Read More]

Islamic perspectives on the embryo and gamete donation

27 October 2008 - by Dr Farrokh B Sekaleshfar

1) The embryo Sunnism and Shi'ism comprise approximately eighty and twenty per cent of the Islamic world, respectively. Like other monotheistic religions, Islam regards one's personal identity, or one's 'I' in terms of personhood, as being tantamount to one's immortal, immaterial and rational soul. Differences between the religions, however, exist... [Read More]

New research sheds light on multiple IVF pregnancies

09 July 2007 - by Sandy Starr

New research into the formation of early embryos (blastocysts) shows how multiple pregnancies resulting from IVF might be explained and reduced, even those where only a single embryo has been implanted. The research was led by Dianna Payne - visiting fellow at the Mio Fertility Clinic in Yonago... [Read More]

FISHing for trouble?

04 December 2006 - by Paul Scriven

Make a habit of two things - to help, or at least to do no harm' (Attr Hippokrates of Kos). The principle of preimplantation testing for sporadic chromosome aneuploidy (preimplantation genetic screening, PGS) to improve the reproductive efficiency of assisted conception for couples at increased risk is a sound one. It... [Read More]

Key fertilisation gene identified

31 October 2005 - by BioNews

Researchers have pinpointed a key gene involved in the successful formation of a zygote (fertilised egg). The team, based at the University of Bath in the UK and the Centre de Genetique Moleculaire et Cellulaire in France, studied the role of the Hira gene during the first 15 minutes after... [Read More]

No more research on 'three-parent embryos'?

16 October 2003 - by BioNews

Researchers from Sun Yat-Sen University in Guangzhou, China have succeeded in creating a pregnancy using an embryo containing the genetic material of three different people. An egg cell taken from one woman was fertilised by in vitro fertilisation (IVF), creating a one-cell embryo, or zygote. The nucleus of the zygote... [Read More]


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