Subscribe to the BioNews newsletter for free

Login
Advanced Search

Search for
BioNews

Like the Progress Educational Trust on Facebook



The Fertility Show, Manchester Central, 24-25 March 2018

Glossary

Mutation

A change in the sequence of DNA. Mutations occurring in genes may prevent them from working properly, which might result in disease (a genetic disorder). Mutations occur naturally at a low rate, but can also be induced by radiation and some chemicals.



Articles using this Glossary Item

 1/44      

Fathers may pass ovarian cancer risk to daughters

19 February 2018 - by Dr Rosie Gilchrist

Scientists have identified a new gene for ovarian cancer risk that may be passed down from fathers to their daughters... [Read More]

Women selected for mitochondrial donation in UK

05 February 2018 - by Sam Sherratt

The Human Fertilisation and Embryology Authority (HFEA) has granted permission for doctors to create the UK's first 'three-person' children by mitochondrial donation.

Blood test for eight common cancers offers promise

22 January 2018 - by Dr Loredana Guglielmi

Scientists have developed a single blood test to detect eight common cancer types and their location of origin within the body... [Read More]

Revolutionising reproduction: setting a new moral compass

22 January 2018 - by Dr Cathy Herbrand

Is sexual reproduction still compatible with Western values? Can germline genome editing ever be considered as medicine? Can we stick to act only on serious disorders? These were some of the provocative and complex questions which were addressed during the last session of the Progress Educational Trust's annual conference... [Read More]

Screening all women over 30 for BRCA could prevent 64,000 cancers

22 January 2018 - by Dr Molly Godfrey

The blanket screening of all women over 30 for genetic mutations which cause breast and, or ovarian cancer could prevent more cancers and be more cost effective than current approaches, according to a new study... [Read More]

BRCA gene does not affect survival in those treated for breast cancer

15 January 2018 - by Hannah Somers

A new study has found that BRCA gene mutations do not affect the survival rates of breast cancer patients under 40... [Read More]

Alcohol found to boost cancer risk by damaging stem cell DNA

08 January 2018 - by Charlott Repschlager

Drinking alcohol damages blood stem cells by altering their DNA, raising the risk of developing cancer, scientists have found.

Gene therapy shows 'mind-blowing' success in treating haemophilia A

18 December 2017 - by Sam Sherratt

A new gene therapy for haemophilia A has exceeded expectations in a recent clinical trial... [Read More]

Mutation that stops people feeling pain found in Italian family

18 December 2017 - by Dr Rachel Huddart

A newly identified genetic mutation causes members of an Italian family to be unable to feel pain and could lead to the development of new painkillers, research suggests... [Read More]

Blood test could warn of return of skin cancer

11 December 2017 - by Shaoni Bhattacharya

UK scientists say they are closer to developing an 'early warning system' for the return of cancer in patients using a simple blood test... [Read More]

First trials of Huntington's drug show it could slow disease

11 December 2017 - by Martha Henriques

A breakthrough trial has successfully reduced levels of the harmful protein that causes the neurodegenerative disease Huntington's... [Read More]

New CRISPR technique reverses diabetes and kidney failure in mice without cutting DNA

11 December 2017 - by Isobel Steer

Scientists in California have used a modified form of the CRISPR/Cas9 genome editing approach to epigenetically treat diabetes, kidney disease and muscular dystrophy in mice... [Read More]

FDA okays test for many cancer-causing genes

04 December 2017 - by Theofanis Michailidis

The US Food and Drug Administration has approved a test which can detect cancer-causing mutations in 324 genes... [Read More]

Event Review: Darwin Lecture: from gene identification to clinical benefit - the example of cystic fibrosis

27 November 2017 - by Lea Goetz

The Darwin lecture held at the UK's Royal Society of Medicine in London, and jointly organised with the Linnean Society, gives an annual look at topics in science and medicine.... [Read More]

Gene conferring long-life identified in US Amish community

20 November 2017 - by Charlott Repschlager

A rare genetic mutation leading to longer and healthier lives has been discovered in the US Amish community... [Read More]

Genetic 'sensor' spots and kill cells with key cancer gene

20 November 2017 - by Marcia Costa

A team of scientists in Germany has developed a 'sensor' that detects mutations in the key tumour suppressor gene p53 and then kills potentially cancerous cells... [Read More]

Two couples sue fertility clinic for providing eggs with genetic abnormalities

20 November 2017 - by Nina Chohan

The New York fertility clinic Reproductive Medicine Associates is facing two lawsuits from couples whose children, conceived using donor eggs from the centre, have Fragile X syndrome... [Read More]

BRCA screening could prevent 1000 cases of breast cancer a year

13 November 2017 - by Dr Loredana Guglielmi

Researchers have introduced new criteria to screen for BRCA gene mutations that could prevent more than 10,000 cases of cancer and save more than 2000 lives in the next decade... [Read More]

Sick boy gets healthy new skin with genetically-altered stem cells

13 November 2017 - by Paul Waldron

A boy with a rare skin disease has been successfully treated by replacing most of his skin with grafts of stem cells modified by gene therapy.

Twenty-seven genes that suppress cancer discovered

06 November 2017 - by Julianna Photopoulos

Scientists have found 27 new tumour suppressor genes... [Read More]

 1/44      


Events using this Glossary Item

Testing, Testing 1, 2, 3: PGS and PGD
13 September 2016 6pm (registration), 6.30pm-8.30pm (discussion) Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH
The Progress Educational Trust's FREE-to-attend event about testing and screening human embryos is taking place TOMORROW EVENING - book NOW. The event will be chaired by Dr Sue Avery, with speakers including Dr Tony Gordon, Dr Christine Patch, James Lawford Davies and Professor Michael Parker...
Risk Assessment: Breast Cancer, Prediction and Screening
08 May 2014 6.30pm-8.30pm Darwin Lecture Theatre, Darwin Building, University College London, Malet Place, London WC1E 6BT
The second FREE public event in the Progress Educational Trust's 'Breast Cancer: Chances, Choices and Genetics' series...
Relative Risk: Breast Cancer and Genetics
03 April 2014 6.30pm-8.30pm Darwin Lecture Theatre, Darwin Building, University College London, Malet Place, London WC1E 6BT
LAST CHANCE to book for this coming Thursday's FREE event launching the Progress Educational Trust's 'Breast Cancer: Chances, Choices and Genetics' project...
Mutants and What to Do About Them
09 February 2011 7.30pm Conway Hall, Red Lion Square, London WC1R 4RL, UK
The 2011 British Humanist Association/South Place Ethical Society Darwin Day Lecture, given by Armand Marie Leroi...
The Blind-Drunk Mutant Mouse: A Model for Schizophrenia?
19 November 2009 12midday Francis Crick Auditorium, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1RQ, UK
A discussion introduced by Professor Kay Davies, Head of Physiology, Anatomy and Genetics at the University of Oxford...
Techniques and Applications of Molecular Biology
13 July 2009  Department of Biological Sciences, Gibbet Hill Campus, Gibbet Hill Road, University of Warwick, Coventry CV4 7AL
A course for those who wish to develop their understanding of genetic engineering techniques...


Published by the Progress Educational Trust
Advertise your products and services HERE - click for further details

Good Fundraising Code

Become a Friend of PET HERE and give the Progress Educational Trust a regular donation