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The Fertility Show

Glossary

Mitochondria

Energy-generating structures found in plant and animal cells. They contain a few genes, which mainly make proteins involved in energy metabolism.



Articles using this Glossary Item

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Smoking while pregnant weakens sons' fertility, mouse study suggests

06 October 2014 - by Dr Charlotte Warren-Gash

Mothers who smoke while pregnant or breastfeeding may reduce their sons' future fertility, according to research... [Read More]

Polygamy left its mark on human genome

29 September 2014 - by Victoria Burchell

The rise of the single mother may seem a rather modern phenomenon. But even before the first humans walked out of Africa 70,000 years ago, mothers have consistently outnumbered fathers, DNA analysis suggests... [Read More]

Mitochondrial donation as a clinical option: A response to Ted Morrow

29 September 2014 - by Professor Frances Flinter

Robust debate about the pros and cons of mitochondrial donation is essential, but the clinical reality of mitochondrial disorders is stark. Couples who have lost a child affected by a serious maternally-inherited mitochondrial disorder may have limited reproductive options... [Read More]

Radio Review: Mum and Dad and Mum

22 September 2014 - by Dr Cathy Herbrand

Following a backbench debate in the House of Commons on mitochondrial donation on 1 September, BBC Radio 4 explored some of the issues raised by these high profile techniques aimed at preventing the transmission of mitochondrial disorders... [Read More]

Myth replacement therapy: MPs debate the science of mitochondria

08 September 2014 - by Dr Ted Morrow

The regulatory path to clinical trials of mitochondrial replacement therapy was recently debated in the House of Commons. While scientists are still unsure how genes and genomes cause disease and impact on our physical appearance and personality, there are clearly misconceptions about mitochondrial genetics repeated during the debate that are not supported by current scientific evidence... [Read More]

Mitochondrial replacement debated in UK Parliament

08 September 2014 - by Sandy Starr

A group of backbench MPs, led by Conservative MP Fiona Bruce, has sought to delay the laying before Parliament of regulations permitting the use of mitochondrial replacement techniques... [Read More]

Government is misleading public about mitochondrial donation, claim scientists

04 August 2014 - by Siobhan Chan

The UK Government has been accused of deliberately misleading the public in order to win approval over its plans to implement mitochondrial replacement techniques in IVF... [Read More]

UK Government plans to legalise mitochondrial replacement for IVF

28 July 2014 - by Rachel Brown

The UK Government has announced that regulations around the use of mitochondrial replacement techniques will be presented to Parliament in the next few months... [Read More]

Event Review: The Ethics of Mitochondrial Replacement Therapy

21 July 2014 - by Professor Vardit Ravitsky, Dr John Appleby, Professor Stephen Wilkinson, Dr Anthony Wrigley and Dr Annelien Bredenoord

Ethical dimensions of the emerging technology of mitochondrial replacement were the focus of a symposium that took place on 25 June at the 12th World Congress of Bioethics in Mexico City.... [Read More]

Farewell from me and welcome to Fiona Fox

16 June 2014 - by Professor Marcus Pembrey

When the Progress Educational Trust - the UK charity that publishes BioNews - emerged from the Progress Campaign for Research into Human Reproduction in 1992, I had no idea that I would end up chairing the Trustees for 20 of the last 22 years!... [Read More]

Mitochondrial replacement likely to be safe but more research needed, says report

09 June 2014 - by Alice Plein

Two experimental IVF techniques that could prevent certain types of incurable genetic disease are 'not unsafe', a report from the UK's Human Fertilisation and Embryology Authority has found.... [Read More]

Is mitochondrial donation 'genetic engineering'?

24 March 2014 - by Professor Janna Thompson

MP Jacob Rees-Mogg recently implied that mitochondrial transfer is akin to eugenics, but it is a way of combating debilitating ailments rather than producing 'perfect' human beings... [Read More]

Conservative MP says mitochondrial donation will produce 'genetically modified children'

17 March 2014 - by Dr Louisa Petchey

The Conservative MP for North East Somerset, Jacob Rees-Mogg, has said that mitochondrial donation will produce 'genetically modified children' with 'three parents', and was 'effectively cloning'... [Read More]

FDA Advisory Committee weighs up mitochondrial replacement

03 March 2014 - by Chee Hoe Low

The USA's Food and Drug Administration (FDA) is considering whether to allow human clinical trials of mitochondrial replacement, an IVF technique that uses gametes from three people... [Read More]

Draft regulations on mitochondrial donation published

03 March 2014 - by Patricia Cassidy

The UK Department of Health has published draft guidelines for the use of new techniques to prevent mothers passing on serious mitochondrial diseases to their children. The guidelines will be the subject of a three-month consultation... [Read More]

Mitochondrial transfer and three-person IVF: What's in a name?

24 February 2014 - by Dr Roger Sturmey

The description of mitochondrial transfer as 'three-person IVF' may conjure up some unnerving perceptions of the consequences, and may be met in the public arena with discomfort, but it's worth considering the fundamental aspects of this approach... [Read More]

Mitochondrial clock used to predict worm lifespan

17 February 2014 - by Chris Baldacci

A technique that accurately predicts the lifespan of nematode worms has been developed by scientists monitoring mitochondrial activity... [Read More]

Questions relating to 'mitochondrial replacement'

10 February 2014 - by Professor Calum MacKellar

Those who are concerned about mitochondrial replacement techniques do not have any less compassion than those who believe that such procedures should be introduced: they just remain to be convinced that all the biological risks have been sufficiently addressed... [Read More]

Response to Professor Calum MacKellar

20 January 2014 - by Professor Sandy Raeburn

Having worked with families affected by genetic disorders for more than 40 years, both in the UK (with its multi-faith society) and in the Sultanate of Oman (where the majority are Muslim but other religions are allowed), I have seen and looked after many people with hereditary illnesses, including those with disabling mitochondrial conditions.... [Read More]

Is mitochondrial replacement therapy eugenic and incompatible with human dignity?

02 December 2013 - by John Appleby, Professor Rosamund Scott and Professor Stephen Wilkinson

A group of European parliamentarians from the Council of Europe recently issued a declaration objecting to the HFEA's policy advice on experimental mitochondrial replacement therapy claiming that MRT is eugenic and inconsistent with human dignity. These are substantial moral claims, ones that deserve closer scrutiny, and it is an interesting and important exercise to consider how successful such arguments are... [Read More]

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Published by the Progress Educational Trust
PET CONFERENCE
COMMERCIALISATION OF LIFE


Lord Robert Winston, Professor of Science and Society at Imperial College London and speaker at the Progress Educational Trust's conference 'The Commercialisation of Life', taking place in central London on Tuesday 2 December

London, 2 December
Click HERE for details

FREE EVENT
HOW SHOULD YOUR DNA BE USED IN THE 100,000 GENOMES PROJECT?


'Genetic Conditions: How Should Your DNA Be Used in the 100,000 Genomes Project?', a FREE public event being organised by the Progress Educational Trust in central London on the evening of Thursday 6 November 2014

London, 6 November
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