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Multidisciplinary PGD: Redesigning the Patient Pathway

Glossary

Mitochondria

Energy-generating structures found in plant and animal cells. They contain a few genes, which mainly make proteins involved in energy metabolism.



Articles using this Glossary Item

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Regeneration of oocytes from discarded genetic material: will this double IVF success rates?

28 November 2016 - by Dr Philip Lewis and Professor Daniel Brison

A major factor limiting the effectiveness of IVF is the availability of high-quality egg cells from a patient. But new research suggests that the use of polar bodies might create two oocytes for the price of one... [Read More]

Lower mitochondria gene activity in brains with Alzheimer's disease

14 November 2016 - by Annabel Slater

Brain tissue from Alzheimer's disease patients shows reduced expression of nuclear genes coding for mitochondrial function... [Read More]

Therapeutic editing of the human genome – Jewish bioethical perspectives

14 November 2016 - by Dr Avi Lerner

Jewish bioethics may help to broaden the discussion of the ethical concerns that emerge from editing the human genome... [Read More]

Autism link to mutations in mitochondria

07 November 2016 - by Helen Robertson

Children with autism spectrum disorder have twice as many harmful mutations in their mitochondrial DNA as their siblings, a study has found... [Read More]

Old drugs: new eggs?

07 November 2016 - by Bethany Muller and Dr Roger Sturmey

Ten years ago, the claim that treatment with cancer drugs can 'grow new eggs' would have been met with incredulity. But a recent study has raised the possibility that ovarian stem cells may be capable of providing new eggs in later life... [Read More]

'Three-person babies' grow up into healthy teenagers

31 October 2016 - by Georgia Everett

Seventeen children conceived through ooplasmic transplantation have all matured with regular health and cognitive abilities, according to a study... [Read More]

Mitochondrial donation technique used in Ukraine, doctors claim

17 October 2016 - by Ayala Ochert

Two women in the Ukraine are pregnant with babies conceived through mitochondrial donation as a treatment for infertility, according to a report in New Scientist... [Read More]

Mitochondrial replacement therapy and the welfare of the child

17 October 2016 - by Dr Mair Crouch

The announcement of the birth of the first child conceived using mitochondrial donation was unforeseen. Nonetheless, in any country regulation should be required to protect the interests of the child... [Read More]

The Mexican mitochondrial case and moral supremacy

10 October 2016 - by Giulia Cavaliere

The announcement of the first baby born using mitochondrial spindle transfer, one of the two techniques that allow the replacement of faulty mitochondrial DNA, caught the UK scientific and bioethics community by surprise... [Read More]

World's first mitochondrial donation baby born

03 October 2016 - by Dr Julia Hill

In a world first, the birth of a baby boy who was conceived using mitochondrial donation has been reported... [Read More]

The Mexican mitochondrial fiasco

28 September 2016 - by César Palacios González

Dr John Zhang's team have opened a new door in terms of reproductive possibilities, but they may very well be instrumental in closing the assisted reproductive door for many people in Mexico... [Read More]

Book Review: GMO Sapiens - The Life-Changing Science of Designer Babies

30 August 2016 - by Julian Hitchcock

GMO Sapiens is just the annoying grit in the machine that the genome editing debate needs, but readers deserve clearer lines between science, speculation and opinion... [Read More]

Event Review: Ethical questions in mitochondrial donation

22 August 2016 - by Dr Reuven Brandt

This transnational symposium on mitochondrial donation covered issues ranging from methodological concerns about the development of policy governing mitochondrial donation, to particular ethical puzzles raised by the implementation of the procedures themselves... [Read More]

Mitochondrial donation case study finally published after 13 years

22 August 2016 - by Dr Özge Özkaya

Chinese researchers say an IVF technique called pronuclear transfer can safely produce a viable pregnancy... [Read More]

Ice-bucket challenge funds ALS gene discoveries

01 August 2016 - by Jenny Sharpe

Donations from the ALS 'ice-bucket challenge' have funded research that has led to the discovery of new genes linked to the disease... [Read More]

Matching mitochondrial and nuclear DNA: Much ado about nothing?

18 July 2016 - by Dr Dusko Ilic

A match of mitochondrial and nuclear genomes apparently affects healthy ageing in mice. But key questions need to be answered before stirring up implications for human mitochondrial replacement therapies... [Read More]

ESHRE 2016: Research highlights

11 July 2016 - by Ayala Ochert

A roundup of research stories from the annual meeting European Society of Human Reproduction and Embryology that hit the headlines this week... [Read More]

Smoking damages sperm through inflammation

04 July 2016 - by Lone Hørlyck

A study of smokers has found smoking damages their sperm, including their DNA and mitochondria, by triggering inflammatory processes in their semen... [Read More]

Sperm self-destruction may lie behind maternal mitochondrial inheritance

04 July 2016 - by Dr Katie Howe

Researchers have identified a gene that, when activated, causes mitochondria inherited from sperm to be destroyed shortly after fertilisation... [Read More]

Video Review: What If My Neighbour's Kid Was Genetically Modified?

04 July 2016 - by Simon Hazelwood-Smith

Paul Knoepfler's TEDx talk covers familiar ground – designer babies, segregation between 'natural' and GM children, unintended side effects, playing god, and eugenics all feature in his dystopian vision of a future involving genetically modified humans... [Read More]

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Events using this Glossary Item

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RETHINKING THE ETHICS OF EMBRYO RESEARCH
Genome Editing, 14 Days and Beyond

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