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Energy-generating structures found in plant and animal cells. They contain a few genes, which mainly make proteins involved in energy metabolism.

Articles using this Glossary Item


UK mitochondrial donation regulations introduced

02 November 2015 - by Dr Katie Howe

Regulations that came into force this week will enable the UK to be the first country in the world to allow the use of mitochondrial donation techniques during IVF... [Read More]

Mitochondrial DNA test improves IVF success rates

26 October 2015 - by Jessica Richardson

A test which measures mitochondrial DNA levels in the embryo could help increase IVF success rates, scientists claim... [Read More]

Video Review: Talking Biopolitics

12 October 2015 - by Dr Rebecca Dimond

Genomic medicine has advanced rapidly in recent years and, with our increasing capacity to collect and store genetic information, it holds not only great promise but also pitfalls, for individuals and communities. This was the topic under discussion in a live video conversation on 7 October, organised by the Center for Genetics and Society... [Read More]

The case against human cloning

28 September 2015 - by Brendan Foht

Compared to the frenzy over human cloning a decade ago, in recent years the issue has received very little political attention. But as the ongoing fights over CRISPR and mitochondrial replacement show, some of the underlying debates are still with us... [Read More]

Cutting-edge technology and mitochondrial diseases - where is the limit?

27 July 2015 - by Dr Dusko Ilic

Given the complexity of the technology, costs and risks involved, two recently described mitochondrial 'gene-correction' strategies will probably remain as proof-of-concept studies and are unlikely be of practical use in clinical medicine in the foreseeable future... [Read More]

Stem cells could treat mitochondrial disease

20 July 2015 - by Julia Hill

Scientists in the USA have demonstrated how stem cell techniques may benefit people with incurable mitochondrial diseases. The research suggests it might be possible one day to replace diseased tissue in patients affected by the disorders... [Read More]

Strong genetic link found for depression

20 July 2015 - by Dr Linda Wijlaars

Two gene variants have been linked to major depressive disorder by an international research consortium... [Read More]

Book Review: One Plus One Equals One - Symbiosis and the Evolution of Complex Life

01 June 2015 - by Isobel Steer

Professor John Archibald masterfully tells the incredible tale of passionate scientists, their hair-raising experiments, and the ancient cellular alliances that spawned multicellular life as we know it... [Read More]

Gene editing of human embryos – more ethical questions to answer

11 May 2015 - by Dr Calum MacKellar

The short article by Robin Lovell-Badge entitled 'Editing human embryos' addressing the work of Junjiu Huang and colleagues in China on gene editing in human embryos - such as the use of the CRISPR/Cas9 system - raises a number of ethical questions.... [Read More]

Genome editing prevents mitochondrial disease in mice

27 April 2015 - by Antony Blackburn-Starza

A gene-editing technique that may prevent mutated mitochondrial DNA from being passed down from mother to child has shown success in an animal study... [Read More]

Leading the way on mitochondrial donation

16 February 2015 - by Professor Frances Flinter

Over the last 30 years I have met some remarkable families, from whom I have learned about the rewards and challenges of caring for relatives with incurable genetic conditions.... [Read More]

Mouse study tests obesity-fertility link

16 February 2015 - by Dr Charlotte Warren-Gash

Obese female mice have lower fertility than healthy weight mice, according to a study led by researchers from the University of Adelaide in Australia... [Read More]

Three parent babies: unethical, unnecessary, unsafe

16 February 2015 - by Philippa Taylor

In a recent Progress Educational Trust debate, 'Mitochondrial Donation: Is It Safe? Is It Ethical?', I spoke about the ethical issues raised by techniques to avoid the passing on of inherited mitochondrial disorders... [Read More]

Mitochondrial Donation: Is It Safe? Is It Ethical?

09 February 2015 - by Rachel Brown

Held at the Houses of Parliament, and organised by the Progress Educational Trust (the charity that publishes BioNews), this public debate was well attended. With all the chairs taken and many more people standing, people clearly felt it was important to discuss these issues... [Read More]

MPs vote overwhelmingly in favour of mitochondrial donation

04 February 2015 - by Sandy Starr

The House of Commons voted by 382 to 128 to pass regulations permitting mitochondrial donation, a majority of 254... [Read More]

Mitochondrial donation: Church of England, Nobel prize winners weigh in on opposite sides

02 February 2015 - by Rebecca Carr

A group of researchers, including five Nobel laureates, has urged the UK's Parliament to legislate for mitochondrial donation... [Read More]

Mitochondrial DNA donors granted anonymity in draft legislation

12 January 2015 - by Rachel Brown

Regulations to legalise and govern the use of mitochondrial donation techniques have been placed before the UK Parliament.... [Read More]

Open letter to UK Parliament: avoid historic mistake on rushing human genetic modification

24 November 2014 - by Dr Paul Knoepfler

Experimental mitochondrial replacement technology has a noble goal, but in my opinion there are too many unanswered questions and risks that remain to allow it to proceed at this time. I believe that moving forward with it would most likely be a tragic mistake for the UK... [Read More]

Smoking while pregnant weakens sons' fertility, mouse study suggests

06 October 2014 - by Dr Charlotte Warren-Gash

Mothers who smoke while pregnant or breastfeeding may reduce their sons' future fertility, according to research... [Read More]

Mitochondrial donation as a clinical option: A response to Ted Morrow

29 September 2014 - by Professor Frances Flinter

Robust debate about the pros and cons of mitochondrial donation is essential, but the clinical reality of mitochondrial disorders is stark. Couples who have lost a child affected by a serious maternally-inherited mitochondrial disorder may have limited reproductive options... [Read More]


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