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Families Through Surrogacy

Glossary

Mitochondria

Energy-generating structures found in plant and animal cells. They contain a few genes, which mainly make proteins involved in energy metabolism.



Articles using this Glossary Item

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Panel recommends FDA approval of mitochondrial donation

08 February 2016 - by Kirsty Oswald

Clinical investigations of mitochondrial donation are 'ethically permissable', says a panel of experts reporting to the US Food and Drug Administration... [Read More]

Meeting Mary Warnock

01 February 2016 - by Dr Kirsty Horsey and Dr Sue Avery

Last November, we accepted an invitation to have coffee and a chat with Mary Warnock. We had no real brief – we just looked forward to a tour through her life and her thoughts on what she had done for the world of assisted reproduction... [Read More]

UK scientists seek trial of 'mitochondria-boosting' IVF technique

01 February 2016 - by Ryan Ross

UK fertility doctors are seeking permission to trial a new IVF treatment that involves transferring additional mitochondria into egg cells before fertilisation... [Read More]

Video Review: Talking Biopolitics – A conversation with Paul Knoepfler and Nathaniel Comfort

01 February 2016 - by Dr Rebecca Dimond

An author and a science historian host an online discussion on the promise and perils of the 'science of designer babies'... [Read More]

Germline in the sand: The ethics and law of engineering the embryo

25 January 2016 - by Antony Blackburn-Starza

We report from the fourth session of annual conference of the Progress Educational Trust, titled 'Germline in the Sand: The Ethics and Law of Engineering the Embryo', which discussed the ethics of human embryo genome editing... [Read More]

Three-person IVF: What makes mitochondrial donation different?

11 January 2016 - by Dr Cathy Herbrand

We report from the second session of the annual conference of the Progress Educational Trust, titled 'From Three-Person IVF to Genome Editing: the Science and the Ethics of Engineering the Embryo', about the newly legalised process of mitochondrial donation... [Read More]

Why the UK should be leading the discussion on embryo engineering

11 January 2016 - by Sarah Pritchard

Sir Mark Walport, the UK's Chief Scientific Adviser, gave the keynote address at the Progress Educational Trust's annual conference, where he highlighted the complexity of assessing emerging science and technology, particularly in relation to genome editing... [Read More]

UK mitochondrial donation regulations introduced

02 November 2015 - by Dr Katie Howe

Regulations that came into force this week will enable the UK to be the first country in the world to allow the use of mitochondrial donation techniques during IVF... [Read More]

Mitochondrial DNA test improves IVF success rates

26 October 2015 - by Jessica Richardson

A test which measures mitochondrial DNA levels in the embryo could help increase IVF success rates, scientists claim... [Read More]

Video Review: Talking Biopolitics - A Conversation with George Annas and Lisa Ikemoto

12 October 2015 - by Dr Rebecca Dimond

Genomic medicine has advanced rapidly in recent years and, with our increasing capacity to collect and store genetic information, it holds not only great promise but also pitfalls, for individuals and communities. This was the topic under discussion in a live video conversation on 7 October, organised by the Center for Genetics and Society... [Read More]

The case against human cloning

28 September 2015 - by Brendan Foht

Compared to the frenzy over human cloning a decade ago, in recent years the issue has received very little political attention. But as the ongoing fights over CRISPR and mitochondrial replacement show, some of the underlying debates are still with us... [Read More]

Cutting-edge technology and mitochondrial diseases - where is the limit?

27 July 2015 - by Dr Dusko Ilic

Given the complexity of the technology, costs and risks involved, two recently described mitochondrial 'gene-correction' strategies will probably remain as proof-of-concept studies and are unlikely be of practical use in clinical medicine in the foreseeable future... [Read More]

Stem cells could treat mitochondrial disease

20 July 2015 - by Julia Hill

Scientists in the USA have demonstrated how stem cell techniques may benefit people with incurable mitochondrial diseases. The research suggests it might be possible one day to replace diseased tissue in patients affected by the disorders... [Read More]

Strong genetic link found for depression

20 July 2015 - by Dr Linda Wijlaars

Two gene variants have been linked to major depressive disorder by an international research consortium... [Read More]

Book Review: One Plus One Equals One - Symbiosis and the Evolution of Complex Life

01 June 2015 - by Isobel Steer

Professor John Archibald masterfully tells the incredible tale of passionate scientists, their hair-raising experiments, and the ancient cellular alliances that spawned multicellular life as we know it... [Read More]

Gene editing of human embryos – more ethical questions to answer

11 May 2015 - by Dr Calum MacKellar

The short article by Robin Lovell-Badge entitled 'Editing human embryos' addressing the work of Junjiu Huang and colleagues in China on gene editing in human embryos - such as the use of the CRISPR/Cas9 system - raises a number of ethical questions.... [Read More]

Genome editing prevents mitochondrial disease in mice

27 April 2015 - by Antony Blackburn-Starza

A gene-editing technique that may prevent mutated mitochondrial DNA from being passed down from mother to child has shown success in an animal study... [Read More]

Leading the way on mitochondrial donation

16 February 2015 - by Professor Frances Flinter

Over the last 30 years I have met some remarkable families, from whom I have learned about the rewards and challenges of caring for relatives with incurable genetic conditions.... [Read More]

Mouse study tests obesity-fertility link

16 February 2015 - by Dr Charlotte Warren-Gash

Obese female mice have lower fertility than healthy weight mice, according to a study led by researchers from the University of Adelaide in Australia... [Read More]

Three parent babies: unethical, unnecessary, unsafe

16 February 2015 - by Philippa Taylor

In a recent Progress Educational Trust debate, 'Mitochondrial Donation: Is It Safe? Is It Ethical?', I spoke about the ethical issues raised by techniques to avoid the passing on of inherited mitochondrial disorders... [Read More]

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