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Glossary

Mitochondria

Energy-generating structures found in plant and animal cells. They contain a few genes, which mainly make proteins involved in energy metabolism.



Articles using this Glossary Item

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Book Review: One Plus One Equals One - Symbiosis and the Evolution of Complex Life

01 June 2015 - by Isobel Steer

Professor John Archibald masterfully tells the incredible tale of passionate scientists, their hair-raising experiments, and the ancient cellular alliances that spawned multicellular life as we know it... [Read More]

Gene editing of human embryos – more ethical questions to answer

11 May 2015 - by Dr Calum MacKellar

The short article by Robin Lovell-Badge entitled 'Editing human embryos' addressing the work of Junjiu Huang and colleagues in China on gene editing in human embryos - such as the use of the CRISPR/Cas9 system - raises a number of ethical questions.... [Read More]

Genome editing prevents mitochondrial disease in mice

27 April 2015 - by Antony Blackburn-Starza

A gene-editing technique that may prevent mutated mitochondrial DNA from being passed down from mother to child has shown success in an animal study... [Read More]

Leading the way on mitochondrial donation

16 February 2015 - by Professor Frances Flinter

Over the last 30 years I have met some remarkable families, from whom I have learned about the rewards and challenges of caring for relatives with incurable genetic conditions.... [Read More]

Mouse study tests obesity-fertility link

16 February 2015 - by Dr Charlotte Warren-Gash

Obese female mice have lower fertility than healthy weight mice, according to a study led by researchers from the University of Adelaide in Australia... [Read More]

Three parent babies: unethical, unnecessary, unsafe

16 February 2015 - by Philippa Taylor

In a recent Progress Educational Trust debate, 'Mitochondrial Donation: Is It Safe? Is It Ethical?', I spoke about the ethical issues raised by techniques to avoid the passing on of inherited mitochondrial disorders... [Read More]

Mitochondrial Donation: Is It Safe? Is It Ethical?

09 February 2015 - by Rachel Brown

Held at the Houses of Parliament, and organised by the Progress Educational Trust (the charity that publishes BioNews), this public debate was well attended. With all the chairs taken and many more people standing, people clearly felt it was important to discuss these issues... [Read More]

MPs vote overwhelmingly in favour of mitochondrial donation

04 February 2015 - by Sandy Starr

The House of Commons voted by 382 to 128 to pass regulations permitting mitochondrial donation, a majority of 254... [Read More]

Mitochondrial donation: Church of England, Nobel prize winners weigh in on opposite sides

02 February 2015 - by Rebecca Carr

A group of researchers, including five Nobel laureates, has urged the UK's Parliament to legislate for mitochondrial donation... [Read More]

Mitochondrial DNA donors granted anonymity in draft legislation

12 January 2015 - by Rachel Brown

Regulations to legalise and govern the use of mitochondrial donation techniques have been placed before the UK Parliament.... [Read More]

Open letter to UK Parliament: avoid historic mistake on rushing human genetic modification

24 November 2014 - by Dr Paul Knoepfler

Experimental mitochondrial replacement technology has a noble goal, but in my opinion there are too many unanswered questions and risks that remain to allow it to proceed at this time. I believe that moving forward with it would most likely be a tragic mistake for the UK... [Read More]

Smoking while pregnant weakens sons' fertility, mouse study suggests

06 October 2014 - by Dr Charlotte Warren-Gash

Mothers who smoke while pregnant or breastfeeding may reduce their sons' future fertility, according to research... [Read More]

Mitochondrial donation as a clinical option: A response to Ted Morrow

29 September 2014 - by Professor Frances Flinter

Robust debate about the pros and cons of mitochondrial donation is essential, but the clinical reality of mitochondrial disorders is stark. Couples who have lost a child affected by a serious maternally-inherited mitochondrial disorder may have limited reproductive options... [Read More]

Polygamy left its mark on human genome

29 September 2014 - by Dr Victoria Burchell

The rise of the single mother may seem a rather modern phenomenon. But even before the first humans walked out of Africa 70,000 years ago, mothers have consistently outnumbered fathers, DNA analysis suggests... [Read More]

Radio Review: Mum and Dad and Mum

22 September 2014 - by Dr Cathy Herbrand

Following a backbench debate in the House of Commons on mitochondrial donation on 1 September, BBC Radio 4 explored some of the issues raised by these high profile techniques aimed at preventing the transmission of mitochondrial disorders... [Read More]

Mitochondrial replacement debated in UK Parliament

08 September 2014 - by Sandy Starr

A group of backbench MPs, led by Conservative MP Fiona Bruce, has sought to delay the laying before Parliament of regulations permitting the use of mitochondrial replacement techniques... [Read More]

Myth replacement therapy: MPs debate the science of mitochondria

08 September 2014 - by Dr Ted Morrow

The regulatory path to clinical trials of mitochondrial replacement therapy was recently debated in the House of Commons. While scientists are still unsure how genes and genomes cause disease and impact on our physical appearance and personality, there are clearly misconceptions about mitochondrial genetics repeated during the debate that are not supported by current scientific evidence... [Read More]

Government is misleading public about mitochondrial donation, claim scientists

04 August 2014 - by Siobhan Chan

The UK Government has been accused of deliberately misleading the public in order to win approval over its plans to implement mitochondrial replacement techniques in IVF... [Read More]

UK Government plans to legalise mitochondrial replacement for IVF

28 July 2014 - by Rachel Brown

The UK Government has announced that regulations around the use of mitochondrial replacement techniques will be presented to Parliament in the next few months... [Read More]

Event Review: The Ethics of Mitochondrial Replacement Therapy

21 July 2014 - by Professor Vardit Ravitsky, Dr John Appleby, Professor Stephen Wilkinson, Dr Anthony Wrigley and Dr Annelien Bredenoord

Ethical dimensions of the emerging technology of mitochondrial replacement were the focus of a symposium that took place on 25 June at the 12th World Congress of Bioethics in Mexico City.... [Read More]

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