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King's College London - Health: More than a medical matter



The process by which certain mammalian genes are switched off during early embryo development, according to whether they were inherited from the father or mother.

Articles using this Glossary Item

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Course Review: Epigenetic Control of Gene Expression

30 September 2013 - by Marco Narajos

There is definitely great scope for expansion in genetics education through online courses, but these should be tailored towards the student's pace, however leisurely that might be... [Read More]

Event Review: It's All in the Genes - Medical Genetics in Obstetrics and Gynaecology

28 May 2013 - by David O'Rourke

Medical genetics has changed how we think about diagnosis and treatment in almost every field of medicine. At an evening event hosted by the Royal Society of Medicine (RSM), medical genetics teamed up with obstetrics and gynaecology to explore the impact of genetics on the diagnosis of ovarian and breast cancer.... [Read More]

Autism mechanism goes beyond genes

29 April 2013 - by Dr Daniel Grimes

A study on identical twins with distinct autistic traits suggests that epigenetic factors may be important in understanding how the neurological disorder develops... [Read More]

Higher birth weight linked to mum's genes

26 March 2012 - by Dr Daniel Grimes

A gene variant passed down from the mother has been linked to heavier newborns, according to scientists... [Read More]

Progress Educational Trust Conference: Growing Concern?

19 December 2011 - by Mila Roode

The consequences of assisted reproductive technology (ART) are a matter of great concern, whether this is the development of the embryo, the perinatal health of the mother, or the ongoing health of the child.... [Read More]

Transferring single embryos: Education ain't enough

23 May 2011 - by Dr Alan Thornhill

When asked why having twins isn't a good idea, I struggle. I start trotting out the party line, the obstetric risks and risks to the babies themselves, and then begin to shuffle my feet. It's complicated, I say, hoping they will move onto another topic... [Read More]

Scientists uncover 'key gene' linked to regulation of body fat

23 May 2011 - by Kimberley Bryon-Dodd

Scientists say they have found a 'master regulator' gene, KLF14, which controls how active some fat metabolism genes are in your fat cells.... [Read More]

Radio Review: Frontiers - Epigenetics

13 December 2010 - by Professor Sandy Raeburn

This Frontiers programme challenged three genetic dogmas. The presenter quoted a recent Observer headline on epigenetics: 'Why everything we were told about evolution was wrong!'... [Read More]

Book Review: The Imprinted Brain - How Genes Set the Balance Between Autism and Psychosis

13 April 2010 - by Ruth Pidsley

The Imprinted Brain sets out a startling new theory that could reshape the way we think about the human brain... [Read More]

A link between male infertility and epigenetic disorders in ART babies?

11 December 2009 - by Dr Rosalind M John

The aim of assisted reproductive technology (ART) is to achieve a single most important goal, the birth of a healthy child. ART is responsible for the birth of over 200,000 children each year worldwide. In the most common form of infertility treatment - IVF - the woman's eggs are collected and then combined with the man's sperm in a petri dish. The successfully fertilised eggs are then transferred into the woman's womb. In ... [Read More]

Sperm linked to ART-related genetic disorders

07 December 2009 - by Dr Vivienne Raper

Mutations in sperm used for in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) may be responsible for causing the rare genetic disorders associated with these techniques... [Read More]

Epigenetics: responding to life by switching genes on and off

07 December 2009 - by Dr Aarathi Prasad

Session 3 of the Progress Educational Trust's annual conference (PET), held on Wednesday 18 November 2009 at Clifford Chance, was chaired by Professor Dian Donnai,Professor of Medical Genetics at the University of Manchester, and started with a talk by Karen Temple, Professor of Medical Genetics and Honorary Consultant in Clinical Genetics at the University of Southampton and Wessex Clinical Genetics Service. Professor Temple gave an intriguing talk on the influence of parent... [Read More]

New study on genetic risks of IVF

23 February 2009 - by Sarah Guy

A large study has investigated the potential genetic risks to children conceived by in vitro fertilisation (IVF). It confirms earlier research indicating that babies born following assisted conception have a small increased risk of certain genetic health problems. The New York Times reports that in November last... [Read More]

The medium is the message: assisted conception and the role of the media

08 September 2008 - by Professor Marcus Pembrey

The Medium is the Message' - a phrase coined by Marshal McLuhan in 1964 - implies that the type of presentation as much as the content of the message determines what gets incorporated into personal and societal views. This 'spin' element has and continues to be a significant component in the media... [Read More]

New study links birth defects with fertility treatments

16 February 2007 - by MacKenna Roberts

Contrary to some earlier findings, a large Canadian study links an increase in birth defects with babies born through fertility treatments. According to the results of the study, which was presented at a Society for Maternal-Fetal Medicine meeting in San Francisco, the overall risk appears minimal - less... [Read More]

IVF embryo culture link to genetic disorder

22 June 2006 - by Dr Jess Buxton

BioNews reporting from ESHRE conference, Prague (sponsored by Planer cryoTechnology). By Dr Jess Buxton: New research on mouse embryos suggests that laboratory culture conditions can affect the activity of several genes. The findings, presented by US scientists at the annual conference of the European Society of Human Reproduction and Embryology... [Read More]

No link between birth defects and fertility treatments

03 November 2005 - by BioNews

Babies conceived using fertility treatments, including IVF, are at no more risk of birth defects than naturally conceived infants, a large US study shows. Researchers at Stamford Hospital in Connecticut looked at data from over 36,000 pregnancies, around five per cent of which arose following fertility treatments. But their findings... [Read More]

Only one genetic imprinting disorder linked to ARTs

24 June 2005 - by BioNews

BioNews reporting from ESHRE conference, Copenhagen: Beckwith-Wiedermann syndrome (BWS) is the only rare genetic 'imprinting' disorder linked to the use of assisted reproduction techniques (ARTs), according to the results of the largest study carried out to date. Researchers at University College in London investigated a possible link between ARTs and... [Read More]

Safety fears over ES cells allayed

06 June 2005 - by BioNews

Human embryonic stem (ES) cells do not show signs of genetic instability when grown for extended periods in the laboratory, UK researchers say. The results, published in the journal Nature Genetics, are 'not only surprising but good news for potential therapeutic use', says study leader Roger Pederson. The scientists, based... [Read More]

Call to track health of IVF children

24 November 2004 - by BioNews

The UK's Medical Research Council (MRC) has published a report highlighting the need for 'improved monitoring and evaluation of assisted reproduction technology (ART)'. Called 'Assisted reproduction: a safe, sound future', the report follows a request from the Human Fertilisation and Embryology Authority (HFEA) asking the MRC to review the evidence... [Read More]

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Events using this Glossary Item


From Imprinting to the Epigenome in 25 years
04 September 2009  Lecture Theatre, Peterhouse College, University of Cambridge, Cambridge CB2 1RD; Kings College, University of Cambridge, King's Parade, Cambridge CB2 1ST, UK
An event celebrating the discovery of imprinting in mammals 25 years ago... [Read More]
Pacific Rim Society for Fertility and Sterility Conference
20 August 2009  Taipei International Convention Centre, 1 Hsin Yi Road, Section 5, Taipei 11049, Taiwan
The 7th Conference of the Pacific Rim Society for Fertility and Sterility... [Read More]

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