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King's College London - Health: More than a medical matter


Gene therapy

A novel technique that aims to treat an illness by replacing a faulty or missing gene with a working copy, or by switching off a harmful gene.

Articles using this Glossary Item

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Radio Review: The Life Scientific - Professor Veronica van Heyningen

07 April 2014 - by Amy Reed

In this week's episode of The Life Scientific, presenter (and physicist) Professor Jim Al-Khalili interviews the recently retired geneticist and discoverer of the PAX6 gene, Professor Veronica van Heyningen.... [Read More]

T-cell gene therapy successful in early clinical trial

24 February 2014 - by Chris Hardy

Researchers trialling a gene therapy-based treatment for leukemia have said the early results go beyond anything they could have thought of in their 'wildest dreams'... [Read More]

Gene therapy looking good for inherited blindness

16 January 2014 - by Siobhan Chan

Gene therapy for an eye condition called choroideremia is safe and has improved the vision of six patients, says a study in the Lancet... [Read More]

Gene therapy promising in Parkinson's patients

10 January 2014 - by Kimberley Bryon-Dodd

Patients in a clinical trial to treat Parkinson's disease with a form of gene therapy have showed signs of significant improvements in their motor-function, according to a report published in the Lancet... [Read More]

Blood cancer sent into remission with gene therapy

16 December 2013 - by Rachel Brown

Gene therapy trials using engineered immune cells have shown considerable progress in treating blood disorders, according to findings presented at the American Society of Hematology's annual meeting... [Read More]

Is mitochondrial replacement therapy eugenic and incompatible with human dignity?

02 December 2013 - by John Appleby, Professor Rosamund Scott and Professor Stephen Wilkinson

A group of European parliamentarians from the Council of Europe recently issued a declaration objecting to the HFEA's policy advice on experimental mitochondrial replacement therapy claiming that MRT is eugenic and inconsistent with human dignity. These are substantial moral claims, ones that deserve closer scrutiny, and it is an interesting and important exercise to consider how successful such arguments are... [Read More]

Gene therapy brings pig hearts back down to size

18 November 2013 - by Siobhan Chan

Heart failure can be reversed using gene therapy, with the effect being amplified when two genes are used together, a study in pigs has found... [Read More]

Clinical-stage gene therapy company launched

11 November 2013 - by Dr Naqash Raja

The Children's Hospital of Philadelphia has invested US $50 million in a biotech start-up in an effort to commercialise gene therapy... [Read More]

Accurate editing of human DNA now possible, say scientists

11 November 2013 - by Anna Cauldwell

A molecular technique that enables any part of the human genome to be altered with extreme precision has been hailed by scientists as a breakthrough in genetics... [Read More]

Genome trawl yields 11 new Alzheimer's risk genes

04 November 2013 - by Rachel Brown

Eleven genetic variants linked to late-onset Alzheimer's disease have been found by the largest study on the genetics behind the condition to date... [Read More]

Mitochondrial replacement IVF: discussions begin in USA

21 October 2013 - by Ruth Saunders

The health regulator in the USA is considering whether clinical trials of mitochondrial replacement techniques should go ahead.... [Read More]

Rare disease treatments risk being 'entirely out of patients' reach', says MPs report

09 September 2013 - by James Brooks

A parliamentary report has recommended a ring-fenced fund to ensure access to 'low volume, high cost' treatments for rare diseases... [Read More]

Early clinical success for stem cell gene therapy in two diseases

15 July 2013 - by Nicola Davis

A clinical trial of a gene therapy to treat children with two types of severe genetic disease has shown early signs of success... [Read More]

The eyes have it: gene therapy delivered to retina in mice

17 June 2013 - by Rhys Baker

A 'non-invasive' method for delivering gene therapy into the eye has been developed by US researchers... [Read More]

Gene therapy against flu tested in animals

03 June 2013 - by Anna Cauldwell

A gene therapy technique can protect mammals from lethal strains of influenza, according to US researchers... [Read More]

Gene therapy trials for heart failure launched

07 May 2013 - by Siobhan Chan

Gene therapy will be used to treat heart failure for the first time in the UK, in clinical trials being launched by the British Heart Foundation... [Read More]

A gene switch for better heart healing in mice

22 April 2013 - by Emma Stoye

Researchers have identified a gene that regulates the regeneration of adult heart cells... [Read More]

Just five patients but gene therapy leukaemia trial yields positive results

25 March 2013 - by John Brinsley

Early results of an experimental gene therapy against an aggressive form of leukaemia have been hailed by researchers as showing 'life saving potential'.... [Read More]

Genetic mutation for mental retardation found in Amish community

18 March 2013 - by Antony Blackburn-Starza

A genetic mutation linked to mental retardation has been identified in an Amish community in the USA.... [Read More]

Gene therapy for osteoarthritis in mice

18 March 2013 - by Reuben Harwood

An experimental gene therapy that protects cartilage from wear and deterioration has been shown to slow the development of osteoarthritis in mice.... [Read More]

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Events using this Glossary Item


Twin Congress on Reproductive Biomedicine and Stem Cell Biology and Technology
23 September 2009  Razi International Conference Centre, Tehran, Iran University of Medical Sciences, Shahid Hemmat Highway 14496, Tehran, Iran
The Royan Institute's 10th Congress on Reproductive Biomedicine and 5th Congress on Stem Cell Biology and Technology... [Read More]
How Do Viruses Treat Cancer?
06 September 2009 1.30pm-5pm High Street, Guildford, Surrey, UK
An exhibition exploring achievements in viral gene therapy for cancer... [Read More]

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