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Glossary

Base-pair

A pair of complementary bases (chemical units that form DNA) in a double-stranded nucleic acid molecule. In DNA, the base adenine (A) always pairs with thymine (T) and the base cytosine (C) always pairs with guanine (G). In RNA, adenine (A) pairs with uracil (U) instead of thymine (T).



Articles using this Glossary Item

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Highly sensitive CRISPR diagnostic tool created

24 April 2017 - by Jennifer Willows and Annabel Slater

A new highly sensitive diagnostic system for diseases has been adapted from CRISPR... [Read More]

Complete synthetic yeast organism almost a reality

13 March 2017 - by Jamie Rickman

An international team has rewritten the genetic code of five chromosomes in yeast – one third of the organism's entire genome... [Read More]

Scientists hold 'secret' meeting on creating synthetic human genome

23 May 2016 - by Arit Udoh

A group of scientists has been criticised for holding a high-level, behind-closed-doors meeting to discuss a project to synthesise a complete human genome within ten years... [Read More]

CRISPR upgrade promises single-letter gene editing

25 April 2016 - by Dr Özge Özkaya

Scientists have fine tuned the genome-editing tool CRISPR so that it can now edit a single 'letter' of DNA... [Read More]

Vegetarian populations carry metabolic mutation

04 April 2016 - by Anastassia Bolotkova

Researchers have found a genetic variant in populations that have favoured vegetarian diets over many generations... [Read More]

World's simplest synthetic cell reveals gaps in genetic knowledge

04 April 2016 - by James Brooks

Scientists have designed and created a functional, self-replicating cell containing only 473 genes – the smallest genome of any organism to be grown in a lab... [Read More]

Ancestral humans had more DNA

17 August 2015 - by Isobel Steer

Compared to ancestral humans, most modern people have lost 40.7 million base pairs of DNA... [Read More]

Film Review: The Lion's Mouth Opens

13 July 2015 - by Dr Julia Hill

Julia Hill reviews 'The Lion's Mouth Opens', a moving portrait of Huntington's Disease... [Read More]

Living in a high-crime area ages your cells

29 June 2015 - by Isobel Steer

Residents of noisy and high-crime neighbourhoods are over a decade older biologically compared with those who live in low-crime areas, according to recent research... [Read More]

Gene variant protects Latin-American women from breast cancer

27 October 2014 - by Arit Udoh

Latin American women are less likely to have breast cancer because of an inherited genetic trait, a study suggests... [Read More]

Scientists engineer organism with expanded genetic alphabet

12 May 2014 - by Siobhan Chan

Bacteria with two extra synthetic DNA bases in their genome have been created in the lab for the first time... [Read More]

Synthetic biology moves beyond bacteria and viruses with 'man-made' yeast chromosome

31 March 2014 - by Rhys Baker

The world's first fully-functional synthetic yeast chromosome has been created in an international seven-year effort... [Read More]

'Big data on steroids': IBM's Watson supercomputer to work on brain cancer genetics

24 March 2014 - by Chris Baldacci

IBM and the New York Genome Centre have teamed up to announce the latest weapon in the fight against cancer - Watson the supercomputer.... [Read More]

There's a new 'fat gene' in town...

17 March 2014 - by Dr Rosie Gilchrist

Scientists have identified a gene called IRX3 which is associated with obesity and may emerge as a serious contender as the most important 'fat gene' yet discovered... [Read More]

Event Review: Genetics and the Prospect of Personalised Medicine for Obesity

10 March 2014 - by Dr James Heather

The media likes to push the idea that the obesity epidemic is fuelled entirely by our increasingly well-fed and sedentary lives, which makes the opportunity to hear solid evidence for the other side of the equation refreshing... [Read More]

Genome engineering company launches with $43 million investments

02 December 2013 - by Dr Rachel Brown

A biotech start-up that will develop genome-editing therapies has received US $43 million investment from three venture capital firms... [Read More]

John Lennon is dead. Long live John G2 (or not)

02 September 2013 - by Dr Dusko Ilic

I could tell straight away that Canadian dentist Michael Zuk, who invested in John Lennon's rotten molar in the hope of cloning the great musician, is a big fan of Michael Crichton's 'Jurassic Park'... [Read More]

Francis Crick's Nobel prize and DNA letter sold for millions

15 April 2013 - by Dr Shanya Sivakumaran

The Nobel prize won by Francis Crick, a British scientist, for his part in the discovery of the double helix structure of DNA, and a handwritten letter recounting this discovery to his 12-year-old son, have been sold for over $8 million this week.... [Read More]

Single gene mutation may be behind type 1 diabetes for minority of patients

11 March 2013 - by Reuben Harwood

Genetic analysis of a family predisposed to type 1 diabetes (T1D) has uncovered the first kind of T1D to be caused by a single gene mutation... [Read More]

Event Review: Masterpieces of Epigenetics - The Missing Link between Nature and Nurture

14 January 2013 - by James Lush

'Beautiful science' was how Dr Nessa Carey described epigenetics at the Biochemical Society Annual Symposium Public Lecture, held at the University of Leeds... [Read More]

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Events using this Glossary Item

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Moving the Boundaries of Human Reproduction

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London
8 December 2017

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Professor Azim Surani

Professor Robin Lovell-Badge

Sally Cheshire

Professor Guido Pennings

Katherine Littler

Professor Richard Anderson

Dr Sue Avery

Dr Elizabeth Garner

Professor Allan Pacey

Dr Anna Smajdor

Dr Andy Greenfield

Philippa Taylor

Dr César Palacios-González

Fiona Fox

Sarah Norcross

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