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Glossary

Blastomeres

Cells produced by the division of the zygote



Articles using this Glossary Item

Preimplantation genetic screening: unvalidated methods discard healthy embryos

11 December 2017 - by Norbert Gleicher

A seemingly brilliant hypothesis of preimplantation genetic screening arose in the 1990s when Dr Yuri Verlinsky proposed using polar body biopsies to detect chromosomal abnormalities in embryos prior to transfer in IVF... Healthy embryos are discarded by unvalidated PGS

With an eye to the future - preliminary results of clinical trial in human embryonic stem cell-based therapy of macular degeneration

31 January 2012 - by Dr Dusko Ilic and Dr Emma Stephenson

Last week, Advanced Cell Technology (ACT) of Massachusetts, USA, made two important announcements regarding human embryonic stem (hES) cell-based therapies for the potential treatment of Stargardt's dystrophy and age-related macular degeneration, two devastating degenerative disease leading to blindness.... [Read More]

What next for preimplantation genetic screening (PGS)?

13 July 2009 - by Dr Joyce Harper

Preimplantation genetic screening (PGS) for aneuploidy was first reported by Verlinsky et al (1995) and Munne et al (1995). Both of these initial studies analysed polar bodies. The aim of the technique is to help determine the best IVF embryo for transfer on the grounds of the polar body or embryo's chromosomes, by performing biopsy and analysis of the chromosomes using fluorescent in situ hybridisation (FISH). There have been hundreds of papers on the use of PGS. It is well known that for pa... [Read More]

New mathematical framework for identifying healthiest IVF embryos

02 March 2009 - by Dr Will Fletcher

Researchers from the University of the Basque Country (UPV-EHU) have developed a new mathematical classification scheme that can be used to select embryos for use in assisted reproduction treatments. The Spanish scientists presented this 'intelligent system' of support for infertility treatments in the journal Computer Methods and... [Read More]


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