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Preimplantation Genetic Diagnosis: The Who, the What, the Why and the How





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The fertility sector should lead the debate on IVF add-ons

19 June 2017 - by Professor Adam Balen
The first in a series of videos filmed at the Progress Educational Trust's recent public debate 'Fertility Treatment Add-Ons: Do They Add Up?'... [Read More]
 

Flushed with success, but we will still need IVF

12 June 2017 - by Stuart Lavery and George Christopoulos
The recent study from Dreyer et al examining the chance of natural pregnancy following hysterosalpingography has provoked a significant amount of interest in the lay press, with suggestions that this well established diagnostic fertility test could be offered therapeutically and be considered as an alternative to IVF... [Read More]
 

Genetic disorders: empowering patients and families through information

12 June 2017 - by Arti Patel
'I've got the diagnosis, now what?' is one of the first questions families ask when they contact us at Unique, the UK-based organisation for rare chromosome and genomic disorders... [Read More]
 

The conceptual foundation of the right to know one's genetic origins

05 June 2017 - by Professor Vardit Ravitsky, Dr Juliet Guichon, Marie-Eve Lemoine, and Professor Michelle Giroux
In his commentary, Professor Guido Pennings argues there is no empirical evidence to support the assumption that it is in the best interests of children to know that they are donor conceived. We would like to add another layer to the critique, by focusing on the conceptual foundation underlying the right of donor-conceived people to know their genetic origins... [Read More]
 

Autism and smoking during pregnancy - a mitochondrial inheritance

30 May 2017 - by Professor David Skuse
In recent years, there has been an explosion in the number of children diagnosed with autism. There is seemingly one in every classroom, most of them boys; some are quiet and nerdy, others may be disruptive and aggressive. Most have normal intelligence, and can be educated in mainstream schools. Parents of such children  question why one child is affected... [Read More]
 

Donor-conceived people do benefit from being told about their conception

30 May 2017 - by Professor Eric Blyth, Dr Marilyn Crawshaw, Iolanda Rodino, and Dr Petra Thorn
Professor Guido Pennings' provocatively entitled BioNews commentary 'Donor children do not benefit from being told about their conception' purports to highlight the shortcomings of existing research supporting a pro-disclosure agenda and castigates counsellors and researchers who advocate parental disclosure... [Read More]
 

Australia upholds the ban on sex selection: a partial victory in an ongoing struggle

22 May 2017 - by Dr Tereza Hendl
Australia recently saw important developments in the field of assisted reproductive technologies, as the National Health and Medical Research Council released its revision of the Part B of the Ethical Guidelines on the Use of Assisted Reproductive Technology in Clinical Practice and Research. Among other topics, this section is concerned with the regulation of sex selection... [Read More]
 

Donation is a hot topic

22 May 2017 - by Sarah Norcross
Last week we published the 900th edition of BioNews, we used this landmark achievement to put out a call for donations but many of you may have missed this as there was so much reaction to a piece we published on donor conception by Professor Guido Pennings... [Read More]
 

If you could alter the characteristics of future generations, would you do it?

22 May 2017 - by Dr Peter Mills
The Nuffield Council on Bioethics is seeking views on the reproductive uses of genome editing in humans. Regular readers of BioNews will know that genome editing (including with the CRISPR-Cas9 technique) offers a way of making precisely targeted modifications to DNA in living cells, harnessing the cells’ inbuilt repair mechanisms to repair a deliberate, double-stranded DNA break in a way that may either disable or introduce a functional DNA sequence... [Read More]
 

A strong and stable BioNews, or a coalition of chaos?

15 May 2017 - by Sarah Norcross
BioNews is publishing its 900th edition today... [Read More]
 

Donor children do not benefit from being told about their conception

15 May 2017 - by Professor Guido Pennings
For some years now, counsellors and psychologists have been spreading the message that it's in the best interest of children to know if they are donor conceived. However, my recent literature review has shown that there is in fact very little empirical evidence to support this position... [Read More]
 

Walking on eggshells? The morally complex practice of egg sharing

15 May 2017 - by Dr Nicky Hudson
BioNews recently reported on the Daily Mail investigation of a so-called 'cash for eggs' scandal which suggested women on low incomes are induced to provide eggs for use in the fertility treatment of others. The coverage, which prompting swift responses from the field, may shock some readers... [Read More]
 

Daily Mail misses the mark on fertility

08 May 2017 - by Professor Adam Balen
Last week the Daily Mail published an undercover investigation into certain aspects of IVF practice in the UK. Whilst this has highlighted some issues, unfortunately the meaning of published statistics has been misinterpreted and certain aspects of the investigation have been given far more weight than is just. Rather than serving the public good, this has the potential to leave vulnerable patients scared and confused.
 

Financial interests and the IVF industry: the Australian case

08 May 2017 - by Dr Jane Williams
Australia's key body for medical research released a new set of ethical guidelines last month on the use of Assisted Reproduction Technologies with a welcome and unusual surprise: a section on conflicts of interest... [Read More]
 

The CRISPR patent dispute - Europe and the US

02 May 2017 - by Brian Nolan
The European Patent Office and the United States Patent and Trademark Office have been thrust into a dispute pitting the University of California, Berkeley and the University of Vienna against the Broad Institute of MIT and Harvard University. Scientists and inventors have been watching the decisions of the EPO and USPTO because these decisions may leave one of these entities with a patent portfolio worth billions of dollars... [Read More]
 

Unproven stem cell therapies – promise versus evidence

02 May 2017 - by Cathal Farrell
The ability of stem cells to divide into different mature cell types has ignited the field of regenerative medicine. Stem cells promise to repair and regenerate damaged or diseased tissues without the need for orthodox medical or surgical interventions. However, there is disparity between the expectations held by the general public and some medical professionals versus the reality of the emerging clinical evidence... [Read More]
 

Is there a right to genetic affinity with one's children?

24 April 2017 - by Dr Megan Allyse
Assisted reproduction returned to the international spotlight last month, when Singapore's highest court penalised a fertility centre that had mistakenly fertilised a woman's eggs with the wrong sperm. The woman and her husband sued for compensation equal to the cost of raising the child until the age of 21, claiming that the clinic's negligence had caused them to give birth to the 'wrong' child... [Read More]
 

Mitochondrial replacement techniques, Mexico and the legal unknowns

24 April 2017 - by Dr César Palacios-González
It is not every day that we can examine the details of the first use of a new reproductive technology. But the first live birth of a baby following the use of a mitochondrial replacement technique (MRT) in IVF last year gives a window into just this. The case – with procedures carried out in both the US and Mexico – also raises legal questions... [Read More]
 

The media, synthetic biology and CRISPR - fears vs. reality

10 April 2017 - by Sean Byrne
A recent Wall Street Journal article, 'DIY Gene Editing: Fast, Cheap — and Worrisome', describes the Saturday afternoon of teenager, Kian Sadeghi, as he learns to use CRISPR/Cas9 at the Genspace Community Lab in Brooklyn, New York. Like many news articles, the main angle of the article is that new science and technology present a problem... [Read More]
 

Fertility treatment add-ons: do they add up?

03 April 2017 - by Antony Blackburn-Starza
The controversial issue of IVF 'add-ons' – techniques and treatments offered to fertility patients on top of standard IVF – has been the subject of intense debate and media attention since last November's BBC Panorama's documentary, which claimed that many techniques advertised on fertility clinics websites were not backed up by good scientific evidence of success... [Read More]
 

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